Infectologia

Outro estudo sugere que há um risco menor de internação e morte na infecção pela variante Ômicron do SARS-CoV-2 vs. a variante Delta.

19 Fev, 2022 | 14:06h

Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada – JAMA

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Diretriz provisória da OMS | Rastreamento de contatos e quarentena no contexto da variante Ômicron do SARS-CoV-2.

19 Fev, 2022 | 14:04h

Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant: interim guidance – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

#COVID19 quarantine period may be shortened for contacts who test negative on a PCR or antigen based rapid diagnostic test. Quarantine can be shortened, for example to seven days, if the contact shows no symptoms & presents a negative test https://t.co/ERF0HDcJOU https://t.co/TsbcHw86B7

— World Health Organization (WHO) (@WHO) February 17, 2022

 

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Revisão | Patogênese e consequências de longo prazo da lesão cardíaca por Covid-19.

19 Fev, 2022 | 14:02h

The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury: State-of-the-Art Review – JACC: Basic to Translational Science

Conteúdo relacionado: COVID-19 infections increase risk of heart conditions up to a year later, study finds.

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Opinião | Os coronavírus são “espertos”: cenários evolutivos para o futuro do SARS-CoV-2.

19 Fev, 2022 | 14:01h

Coronaviruses are ‘clever’: Evolutionary scenarios for the future of SARS-CoV-2 – STAT

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Perspectiva | Estamos entrando na fase de controle da pandemia.

19 Fev, 2022 | 13:59h

We’re Entering the Control Phase of the Pandemic – The Atlantic

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Revisão | Doenças por riquétsias como causa de doença febril aguda.

19 Fev, 2022 | 13:30h

Rickettsial illnesses, a leading cause of acute febrile illness – Clinical Medicine Journal

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Dengue: importância global, imunopatologia e tratamento.

19 Fev, 2022 | 13:28h

Dengue infection: Global importance, immunopathology and management – Clinical Medicine Journal

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Leptospirose: aspectos clínicos.

19 Fev, 2022 | 13:27h

Leptospirosis: clinical aspects – Clinical Medicine Journal

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Revisão | Infecções neurológicas tropicais emergentes.

19 Fev, 2022 | 13:26h

Emerging tropical neurological infections – Clinical Medicine Journal

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Estudo randomizado | Nirmatrelvir oral para adultos de alto risco com Covid-19 reduz em 89% o risco de internação.

17 Fev, 2022 | 15:37h

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Entrevista em áudio: A New Antiviral against Covid-19 – new England Journal of Medicine

Conteúdos relacionados:

[Press release – not published yet] Pfizer’s Covid pill remains 89% effective for reducing the risk of hospitalization or death in final analysis.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

 

Comentário no Twitter

The Paxlovid pill (Nirmatrelvir) randomized, placebo-controlled trial published @NEJM:
89% efficacy vs Covid hospitalizations or deaths, and quick reduction of viral load.
The active pills had less serious adverse events or discontinuations than placebohttps://t.co/HBMRZt4wBo pic.twitter.com/LDQv41O56c

— Eric Topol (@EricTopol) February 16, 2022

 

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