Infectologia

Dois amplos estudos de base populacional mostram um risco ligeiramente aumentado de eventos trombóticos após vacinação contra COVID-19 com a vacina da AstraZeneca.

24 Fev, 2022 | 15:47h

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England – PLOS Medicine

Ver também: First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales – PLOS Medicine

Comentários:

Two studies find only small elevated risk of blood clots following AstraZeneca COVID-19 vaccination – PLOS

Two Large Studies Affirm Rare Thrombosis Risk With ChAdOx1 COVID-19 Vax – TCTMD

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Estudo randomizado | Descontinuação do metotrexato por 2 semanas em pacientes com artrite reumatoide imunizados com vacina de SARS-CoV-2 inativado.

24 Fev, 2022 | 15:44h

Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial – Annals of Rheumatic Diseases

Comentário: Suspend Methotrexate for RA Patients Getting COVID Vax?— It’s not a simple choice, Brazilian study suggests (necessário cadastro gratuito)

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Mortalidade por síndrome do Zika congênita – Estudo de coorte nacional no Brasil.

24 Fev, 2022 | 15:43h

Mortality from Congenital Zika Syndrome — Nationwide Cohort Study in Brazil – New England Journal of Medicine

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M-A | Acurácia diagnóstica de testes “point-of-care” nas infecções agudas de trato respiratório inferior adquiridas na comunidade.

24 Fev, 2022 | 13:37h

Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections. A systematic review and meta-analysis – Clinical Microbiology and Infection

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Opinião do Dr. Eric Topol | Por que uma única dose de vacina após infecção por Covid-19 deveria ser suficiente para se considerar uma vacinação completa.

22 Fev, 2022 | 15:42h

Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed – The Guardian

 

Comentário do autor no Twitter (fio – clique para saber mais)

My new essay @guardian
"Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed"https://t.co/RaBUpET2CZ
Summarizes extensive new evidence that confirmed Prior Covid ("Natural Immunity" or NI) + 1-shot is as protective as 3-shots /1

— Eric Topol (@EricTopol) February 20, 2022

 

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Metanálise mostra que há baixo risco de uma segunda reação alérgica a vacinas de mRNA contra SARS-CoV-2 em pacientes que apresentaram tal reação na primeira dose.

22 Fev, 2022 | 15:40h

Risk of Second Allergic Reaction to SARS-CoV-2 Vaccines: A Systematic Review and Meta-analysis – JAMA Internal Medicine

 

Comentário no Twitter

Systematic review and meta-analysis of 22 studies and 1366 patients found that there was a low risk of repeat allergic reaction to a second #COVID19 mRNA vaccine dose in people who had immediate allergic reaction with the first dose. https://t.co/NQSXBJwa6r

— JAMA Internal Medicine (@JAMAInternalMed) February 21, 2022

 

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[Preprint] Um estudo observacional de larga escala feito no Chile mostrou que a CoronaVac (vacina de SARS-CoV-2 inativado) foi associada com efetividade de 74,5% contra infecção, 91% contra internação e 93,8% contra admissão em UTI em crianças de 6 a 16 anos de idade.

22 Fev, 2022 | 15:38h

Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Children and Adolescents: A Large-Scale Observational Study – Preprints with The Lancet

Comentário: Full schedule of CoronaVac vaccine shown to be highly effective in children – News Medical

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Reino Unido revela planos para “conviver com a COVID”.

22 Fev, 2022 | 15:37h

UK unveils game plan for ‘living with COVID’ – CIDRAP

Ver também:

All you need to know about the end of Covid rules in England – The Guardian

‘Living with Covid’ strategy could do more harm than good, say businesses and unions – The Guardian

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Por que a subvariante Ômicron se dissemina mais rápido que a original?

22 Fev, 2022 | 15:35h

Why does the Omicron sub-variant spread faster than the original? – Nature

Conteúdos relacionados:

Conflicting reports raise questions about whether any monoclonals work against Omicron’s sister variant.

Covid-19: What do we know about omicron sublineages?

We regret to inform you that we are now discussing subvariants – Vox

Sudden rise of more transmissible form of Omicron catches scientists by surprise.

Omicron’s sister variant spreads faster. So why did the one we call Omicron hit first?

[Preprint] Study suggests SARS-CoV-2 Omicron subvariants BA.2 is even more transmissible than the original variant.

BA.2 is like Omicron’s sister. Here’s what we know about it so far – The Conversation

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Podcast | Dicas e truques para tratamento da infecção por helicobacter.

22 Fev, 2022 | 15:28h

Podcast: #322 H. Pylori Infection – The Curbsiders

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