Acesso livre
Acesso livre

Infectologia

Estudo randomizado | Efeito da otimização de doses com base no monitoramento medicamentoso de piperacilina/tazobactam na disfunção de órgão relacionada a sepse em pacientes sépticos.

3 Mar, 2022 | 16:31h

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial – Intensive Care Medicine

 

Comentário no Twitter

 

Revisão | Coccidioidomicose.

3 Mar, 2022 | 15:48h

Coccidioidomycosis: A Contemporary Review – Infectious Diseases and Therapy

Diretriz | Tratamento da infecção por Clostridioides difficile em receptores de transplante de células hematopoiéticas.

3 Mar, 2022 | 15:47h

American Society for Transplantation and Cellular Therapy Series: #5 – Management of Clostridioides difficile infection in hematopoietic cell transplant recipients – Transplantation and Cellular Therapy

Ver outros artigos da série:

American Society of Transplantation and Cellular Therapy Series, 1: Enterobacterales Infection Prevention and Management after Hematopoietic Cell Transplantation

 

American Society of Transplantation and Cellular Therapy Series, 2: Management and Prevention of Aspergillosis in Hematopoietic Cell Transplantation Recipients

 

American Society for Transplantation and Cellular Therapy Series: #3—Prevention of Cytomegalovirus Infection and Disease After Hematopoietic Cell Transplantation

 

American Society for Transplantation and Cellular Therapy Series: #4 – Cytomegalovirus treatment and management of resistant or refractory infections after hematopoietic cell transplantation

Revisão JACC | Anticoagulação em pacientes com COVID-19.

2 Mar, 2022 | 11:42h

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Comentário: Review of Anticoagulation in Patients With COVID-19: Key Points – American College of Cardiology

Prescrição de nirmatrelvir-ritonavir para Covid-19: como reconhecer e administrar as interações medicamentosas.

2 Mar, 2022 | 11:40h

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

Conteúdos relacionados:

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

Pfizer antiviral pills may be risky with other medications – NBC News

The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist

Estudos sugerem que mercado de Wuhan foi o epicentro do início da pandemia.

2 Mar, 2022 | 11:38h

Wuhan market was epicentre of pandemic’s start, studies suggest – Nature

Conteúdos relacionados:

[Preprint] SARS-like viruses may jump from animals to people hundreds of thousands of times a year.

Did the coronavirus jump from animals to people twice? – Nature

The Origins of SARS-CoV-2: A Critical Review.

The animal origin of SARS-CoV-2 – “Trading of animals susceptible to bat coronaviruses is the likely cause of the COVID-19 pandemic”.

Fauci says natural origins theory of coronavirus is still the most likely.

 

Comentário no Twitter

 

Diretrizes clínicas SEOM para profilaxia de doenças infecciosas em pacientes oncológicos.

2 Mar, 2022 | 11:35h

SEOM clinical guidelines for the prophylaxis of infectious diseases in cancer patients – Clinical and Translational Oncology

Diretriz atualizada | Momento da cirurgia eletiva e avaliação de risco após infecção por SARS-CoV-2 – “Mantemos a orientação de que os pacientes devem evitar cirurgias eletivas dentro de 7 semanas da infecção, a menos que os benefícios superem o risco de aguardar por tal período.”

1 Mar, 2022 | 15:38h

Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia

Conteúdos relacionados:

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

[Preprint] Estudo mostra efetividade significativamente reduzida da vacina da Pfizer em crianças de 5 a 11 anos após o surgimento da variante Ômicron.

1 Mar, 2022 | 15:36h

Effectiveness of the BNT162b2 vaccine among children 5-11 and 12-17 years in New York after the Emergence of the Omicron Variant – medRxiv

Comentários:

Pfizer Covid vaccine is less effective in kids 5 to 11, study finds – STAT

Pfizer Covid-19 vaccine effectiveness fell quickly for kids during Omicron surge but still offered some protection against severe disease – CNN

More mask mandates fall as poor COVID vaccine protection noted in young kids – CIDRAP

Câncer orofaríngeo associado ao HPV: epidemiologia, biologia molecular e tratamento clínico.

1 Mar, 2022 | 15:03h

HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management – Nature Reviews Clinical Oncology (se o acesso a este link for pago, tente este)

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