Acesso livre
Acesso livre

Infectologia

Estudo randomizado | Efeito da antibioticoterapia inicial guiada por coloração de Gram sobre a resposta clínica de pacientes com pneumonia associada a ventilador.

12 Abr, 2022 | 12:35h

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Comentário: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (necessário cadastro gratuito)

 

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M-A | Padrões de trombose e desfecho clínico da trombocitopenia trombótica imune induzida por vacina contra COVID-19.

11 Abr, 2022 | 12:58h

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Conteúdos relacionados:

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (vários artigos e fontes sobre o tema)

Consenso: COVID longa em crianças.

11 Abr, 2022 | 12:57h

Long COVID (post-COVID-19 condition) in children: a modified Delphi process – Archives of Disease in Childhood

Conteúdos relacionados:

First research definition for ‘Long COVID’ in kids and young people formally agreed.

Cohort Study: Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Opinião | Por que demorou 2 anos para a OMS dizer que a COVID é transmitida pelo ar.

11 Abr, 2022 | 12:55h

Why the WHO took two years to say COVID is airborne – Nature

M-A | Desempenho diagnóstico do CO-RADS para Covid-19.

11 Abr, 2022 | 12:53h

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Conteúdos relacionados: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology

Revisão | Dor crônica e infecção: mecanismos, causas, condições, tratamentos e controvérsias.

11 Abr, 2022 | 12:51h

Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies – BMJ Medicine

Intervenções para tratar infecções de corrente sanguínea relacionadas a cateter em pessoas sob hemodiálise de manutenção.

11 Abr, 2022 | 12:46h

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

Resumo: Interventions for treating catheter-related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

Estudo mostra risco aumentado de embolia pulmonar em até 110 dias após a COVID-19.

8 Abr, 2022 | 21:58h

Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study – The BMJ

Comunicado de imprensa: Study finds increased risk of serious blood clots up to six months after COVID-19 – BMJ

Editorial: Thromboembolism and bleeding after covid-19

Comentário: Covid: Blood clot risk higher for six months after having virus – BBC

COVID-19: diretriz conjunta do ECDC e EMA sobre a 4ª dose de vacinas de mRNA.

8 Abr, 2022 | 21:56h

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines –
European Centre for Disease Prevention and Control

Conteúdos relacionados:

Observational study suggests a fourth dose of the Pfizer vaccine provided additional protection against severe disease in patients 60 years of age or older during the Omicron wave in Israel.

Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

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Estudo randomizado pragmático | Em pacientes ambulatoriais com COVID-19, a adição da oximetria de pulso para monitoramento não melhorou os desfechos em comparação a avaliações subjetivas isoladas da dispneia.

8 Abr, 2022 | 21:54h

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

 

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