Infectologia

Diretrizes | Tratamento de infecções recorrentes de trato urinário em mulheres.

19 Mai, 2022 | 13:07h

Guideline of guidelines: management of recurrent urinary tract infections in women – BJU International

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Atualização clínica da COVID-19 para o médico emergencista: parada cardíaca dentro e fora do ambiente hospitalar.

18 Mai, 2022 | 17:01h

Clinical update on COVID-19 for the emergency clinician: Cardiac arrest in the out-of-hospital and in-hospital settings – The American Journal of Emergency Medicine

Conteúdos relacionados:

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine

Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation – The American Journal of Emergency Medicine

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Estudo RECOVERY | Por questões de segurança, o recrutamento de pacientes com Covid-19 apresentando hipóxia sem oxigênio ou recebendo oxigênio simples para doses mais altas de corticosteroides foi encerrado.

18 Mai, 2022 | 17:00h

Recruitment to higher dose corticosteroids closed for patients with hypoxia on no oxygen or receiving simple oxygen – University of Oxford

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Estudo de coorte | Trombose venosa ou arterial e mortes em casos de COVID-19.

18 Mai, 2022 | 16:58h

Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study – The Lancet Infectious Diseases

Comentário convidado: Risk of arterial and venous thromboses after COVID-19 – The Lancet Infectious Diseases

Comunicado de imprensa: COVID-19’s high blood clot risk – University of Oxford

 

Comentário no Twitter

Clots with Covid: Multi-national report of over 900,000 people indicates propensity of risk for arterial and venous thrombi is in men, with increasing age, and association with fatalities (4-fold in non-hospitalized) https://t.co/muGnDld4Um pic.twitter.com/6bLiHPLInm

— Eric Topol (@EricTopol) May 13, 2022

Sob licença de Creative Commons Attribution (CC BY 4.0)

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Estudo de coorte | Risco de morte e reinternação não planejada após alta hospitalar de internação por COVID-19.

18 Mai, 2022 | 16:56h

The risk of death or unplanned readmission after discharge from a COVID-19 hospitalization in Alberta and Ontario – Canadian Medical Association Journal

Comentário: Study: Readmission rate for COVID-19 is 11% – CIDRAP

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Estudo randomizado | Antibioticoprofilaxia de longa duração na amputação de membro inferior.

18 Mai, 2022 | 16:49h

Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial – British Journal of Surgery (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

In the May issue of BJS: Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial https://t.co/2H0TthufvZ @AmyLightnerMD @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @robhinchliffe1 @young_bjs pic.twitter.com/taSa4Caibn

— BJS (@BJSurgery) April 30, 2022

 

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Comentário de estudo | Antibióticos para pneumonia pediátrica: menos pode ser suficiente?

18 Mai, 2022 | 16:42h

Antibiotics for Pediatric Pneumonia: Might Less Be Enough? – Annals of Emergency Medicine

Estudo original: Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Conteúdos relacionados:

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

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Estudo randomizado | Efeito da posição prona na entubação endotraqueal de pacientes com COVID-19 e insuficiência respiratória aguda.

17 Mai, 2022 | 12:13h

Effect of Awake Prone Positioning on Endotracheal Intubation in Patients With COVID-19 and Acute Respiratory Failure: A Randomized Clinical Trial – JAMA

Conteúdos relacionados:

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

 

Comentário no Twitter

In this trial, in patients with acute hypoxemic respiratory failure from #COVID19, prone positioning, compared with usual care without prone positioning, did not significantly reduce endotracheal intubation at 30 days. https://t.co/1RyYRtcrYj

— JAMA (@JAMA_current) May 15, 2022

 

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Estudo randomizado | Comparação de antibioticoterapia por 8 vs. 15 dias para pneumonia por Pseudomonas aeruginosa associada a ventilador mecânico em adultos.

17 Mai, 2022 | 12:07h

Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial – Intensive Care Medicine (artigo gratuito aqui)

 

Comentário no Twitter

🧫 8 vs 15 days ABT for Pseudomonas aeruginosa VAP in adults, iDIAPASON RCT: no differences in composite or separate outcomes (90-day mortality/VAP recurrence) between short & long duration treatment.
📢 @yourICM ground-breaking release #LIVES40 #FOAMcc
🖇 https://t.co/LfoUWxCkkl pic.twitter.com/XaWkQ5R6wT

— Intensive Care Medicine (@yourICM) May 13, 2022

 

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Estudo de caso-controle e teste negativo | Associação entre vacinação prévia com BNT162b2 contra COVID-19 e infecção sintomática por SARS-CoV-2 em crianças e adolescentes durante a predominância da variante Ômicron.

17 Mai, 2022 | 12:04h

Association of Prior BNT162b2 COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection in Children and Adolescents During Omicron Predominance – JAMA

Estudo relacionado: Risk of Infection and Hospitalization Among Vaccinated and Unvaccinated Children and Adolescents in New York After the Emergence of the Omicron Variant – JAMA

Editorial: Protecting Children Against Omicron – JAMA

 

Comentário no Twitter (fio – clique para saber mais)

This new JAMA study is worth discussing. It found that, this winter, vax effectiveness in 12-15 yos dropped to 0% after 3-5 months & vaccinated were MORE likely to test+ at month 7. May be confounded (see🧵)
But I don't see this as good reason for boostershttps://t.co/zpkIDdZhnn pic.twitter.com/bxAIDmiR8s

— Tracy Høeg, MD, PhD (@TracyBethHoeg) May 14, 2022

 

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