Acesso livre
Acesso livre

Infectologia

Estudo randomizado | Segurança e imunogenicidade da imunização com reforço heterólogo usando Ad5-nCoV em aerossol oral após 2 doses prévias de vacina com SARS-CoV-2 inativado em adultos na China.

24 Mai, 2022 | 11:52h

Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial – The Lancet Respiratory Medicine

 

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Estudo randomizado | Oxigênio nasal de alto fluxo não é benéfico para pacientes com pneumonia por Covid-19 e hipoxemia leve.

24 Mai, 2022 | 11:51h

High-flow nasal oxygen versus conventional oxygen therapy in patients with COVID-19 pneumonia and mild hypoxaemia: a randomised controlled trial – Thorax


O que está mandando as crianças para o hospital com hepatite – coronavírus, adenovírus ou ambos?

24 Mai, 2022 | 11:48h

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Conteúdos relacionados:

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press


OMS | Surto de varíola dos macacos em muitos países não endêmicos.

24 Mai, 2022 | 11:46h

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 

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OMS valida a 11ª vacina contra COVID-19.

23 Mai, 2022 | 13:37h

WHO validates 11th vaccine for COVID-19 – World Health Organization

 

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Evidência sobre COVID-19: uma coletânea Cochrane.

23 Mai, 2022 | 13:36h

COVID-19 evidence: a Cochrane round-up – Cochrane Library


Revisão sistemática | Exames de imagem torácica para diagnóstico de COVID-19.

23 Mai, 2022 | 13:34h

Thoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library

Resumo: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library

Conteúdo relacionado: Review of Thoracic Imaging Manifestations of COVID-19 and Other Pathologic Coronaviruses – Radiology Clinics of North America


M-A | Duração do curso de antibióticos para pneumonia adquirida na comunidade em pacientes pediátricos ambulatoriais em países de alta renda – Tratamento com duração de 3-5 dias é tão efetivo e seguro quanto 7-10 dias.

23 Mai, 2022 | 13:33h

Antibiotic treatment duration for community acquired pneumonia in outpatient children in high-income countries – a systematic review and meta-analysis – Clinical Infectious Diseases

Conteúdos relacionados:

Antibiotics for Pediatric Pneumonia: Might Less Be Enough? – Annals of Emergency Medicine

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 

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Covid-19 | OMS afirma que o segundo reforço de vacina pode ser benéfico em grupos de alto risco, mas tem um impacto “mínimo” para outros grupos.

23 Mai, 2022 | 13:31h

Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO – The BMJ

Diretriz original: Interim statement on the use of additional booster doses of Emergency Use Listed mRNA vaccines against COVID-19 – World Health Organization

Recomendações relacionadas:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines –
European Centre for Disease Prevention and Control

Coronavirus (COVID-19) Update: FDA Authorizes Second Booster Dose of Two COVID-19 Vaccines for Older and Immunocompromised Individuals – U.S. Food & Drug Administration


Reativação sanguínea do citomegalovírus em pacientes críticos com COVID-19: fatores de risco e impacto sobre a mortalidade.

23 Mai, 2022 | 13:29h

Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality – Intensive Care Medicine

 

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