Infectologia
Vacinas contra COVID: o perigo de publicações científicas serem vistas como substitutas de agências reguladoras – “o processo de revisão pelos pares não é adequado para avaliar uma nova vacina com a mesma capacidade de uma agência reguladora.”
20 Mai, 2021 | 10:53hCOVID vaccines: the danger of journals being seen as substitute regulators – The Conversation
Relacionado: Covid-19: Sputnik vaccine rockets, thanks to Lancet boost
Um programa de avaliação de alergia à penicilina, conduzido por farmacêutico, pode desclassificar muitos pacientes “alérgicos à penicilina” por meio de seus históricos de alergia e testes cutâneos de penicilina. O programa foi associado à redução no uso de antibióticos com alto risco para infecção por Clostridioides difficile.
20 Mai, 2021 | 10:48h
Comentários no Twitter
🆕💥💥 @jamanetworkopen
Evaluation of a Pharmacist-Led Penicillin Allergy Assessment Program and Allergy Delabeling in a 3ry Care Hospital
Phase 1 : Allergy histories
Phase 2 :Allergy histories +Penicillin Skin Testing #IDTwitter https://t.co/pZfVf8TJIn pic.twitter.com/2VvnaCayqj— Antibiotic Steward 🇵🇸💔Bassam Ghanem (@ABsteward) May 13, 2021
This cross-sectional study found pharmacist-driven allergy assessments may help improve antibiotic selection and clinical outcomes for patients and hospitals https://t.co/io5LcU9U9U
— JAMA Network Open (@JAMANetworkOpen) May 13, 2021
M-A: Em comparação à cefazolina isolada, cefazolina + profilaxia com macrolídios ou metronidazol antes da incisão reduz a incidência de infecção no sítio cirúrgico pós-cesariana e o período de internação hospitalar.
20 Mai, 2021 | 10:44hPre-incision Adjunctive Prophylaxis for Cesarean Sections: A Systematic Review and Meta-analysis – American Journal of Obstetrics & Gynecology (link para o resumo – $ para o texto completo)
[Preprint] Estudo RECOVERY: Colchicina não melhora os desfechos em pacientes com COVID-19 admitidos em hospital.
19 Mai, 2021 | 09:51h
Comentário no Twitter (fio – clique para saber mais)
RECOVERY pre-print: Colchicine
11340 patients hospitalised with COVID-19
Randomised to colchicine vs usual care
No significant improvement in:
– 28-day mortality
– discharge alive at 28 days
– progression to invasive mechanical ventilation or deathhttps://t.co/mEtYq2qwkL pic.twitter.com/B0MNJWDi6e— Martin Landray (@MartinLandray) May 18, 2021
SARS-CoV-2 infecta e compromete as células beta pancreáticas humanas.
19 Mai, 2021 | 09:50hSARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment – Cell Metabolism
Relacionado: Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology
Comentário no Twitter
A new report reinforces the capability for #SARSCoV2 to infect and kill pancreatic β-islet cells, affect insulin secretion https://t.co/4tpIVNpjTf @Cell_Metabolism #diabetes @StanfordMed @stanfordimmuno @UCSF and collaborators pic.twitter.com/dG027CXS5e
— Eric Topol (@EricTopol) May 18, 2021
Perspectiva | Covid-19: O que deveríamos fazer sobre a variante B.1.617.2? O clássico caso de tomada de decisão diante de incertezas.
19 Mai, 2021 | 09:48hEstudo da OMS “Solidarity” irá ser reiniciado com foco em medicamentos que agem sobre as respostas imunes geradas pela Covid-19.
19 Mai, 2021 | 09:47hInternational COVID-19 trial to restart with focus on immune responses – Nature
Revisão: Testagem em escala durante a pandemia de COVID-19.
19 Mai, 2021 | 09:46hTesting at scale during the COVID-19 pandemic – Nature Reviews Immunology
Comentário no Twitter
🆕💥 @NatureRevGenet
Testing at scale during the COVID-19 pandemic
💥Changes in modes of testing across a generalized COVID-19 infectious course💥
✨Excellent Figure ✨ https://t.co/sUZjRr1gQR pic.twitter.com/ZiOXCw7en2— Antibiotic Steward 🇵🇸💔Bassam Ghanem (@ABsteward) May 10, 2021
Opinião | Vacinar crianças antes dos pobres é moralmente errado, afirma cientista de Oxford.
19 Mai, 2021 | 09:45hVaccinating children before poor morally wrong, Oxford scientist says – BBC
Relacionado: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme E Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. E Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”.
Ex-diretor do CDC: É Preciso destinar vacinas contra Covid-19 para onde elas são mais necessárias.
19 Mai, 2021 | 09:44hFormer CDC director: Direct Covid-19 vaccines to where they’re needed most – CNN
Comentário no Twitter
Vaccine inequity is a serious problem ethically and epidemiologically. Read my latest at @CNN on why we must direct Covid vaccines to where they’re needed the most. https://t.co/2CD5xzI00h
— Dr. Tom Frieden (@DrTomFrieden) May 17, 2021