Infectologia
OMS | Novo estudo destaca a prevalência global inaceitavelmente alta de sífilis entre homens que fazem sexo com homens.
14 Jul, 2021 | 11:35hEstudo original: Prevalence of syphilis among men who have sex with men: a global systematic review and meta-analysis from 2000–20 – The Lancet Global Health
Comentário: Syphilis in men who have sex with men: advancing research and human rights – The Lancet Global Health
Diretriz nacional alemã para tratamento de pacientes hospitalizados com COVID-19.
13 Jul, 2021 | 11:30hAmpla análise genômica identificou 13 novas regiões genômicas associadas a suscetibilidade e gravidade da Covid-19.
13 Jul, 2021 | 11:29hMapping the human genetic architecture of COVID-19 – Nature
Comentários: The quest to find genes that drive severe COVID – Nature E Gene hunters turn up new clues to help explain why Covid-19 hits some people so hard – STAT E Large genomic analysis highlights COVID-19 risk factors – Broad Institute of MIT and Harvard E A new study finds genetic variations in Covid patients that could point to better drug treatments. – The New York Times E How your DNA may affect whether you get COVID-19 or become gravely ill – ScienceNews
“Long Covid”: 39% dos pacientes tratados em ambulatório relatam sintomas persistentes mais de 7 meses depois do diagnóstico de COVID-19.
13 Jul, 2021 | 11:28hComentários: Long COVID symptoms in a third of people with COVID-19 – American College of Physicians E Covid-19: 1-in-3 Patients Reported Long-Hauler Symptoms – Physician’s Weekly
Comentário no Twitter
A new prospective cohort study of >400 people with mild to moderate (outpatient) covid at 7-9 months: nearly 1 of 3 had persistent symptoms #LongCovid @AnnalsofIM
https://t.co/ix1Hhsm0iZ
by @mayssamnehme and colleagues pic.twitter.com/Uc4UEclDvA— Eric Topol (@EricTopol) July 5, 2021
[Preprint] “Long Covid”: sintomas persistentes após infecção por SARS-CoV-2 em uma amostra aleatória de 508.707 pessoas da comunidade.
13 Jul, 2021 | 11:27hComentário: Study explores the prevalence of long COVID in England – News Medical
OMS alerta quanto à mistura e à combinação de vacinas contra a COVID.
13 Jul, 2021 | 11:26hWHO warns against mixing and matching COVID vaccines – Reuters
Comentário: WHO cautions data still limited on mixing COVID-19 vaccines, but Canadian officials say it’s OK – CTV News
Relacionado: Germany issues world’s strongest recommendation for mixing Covid-19 vaccines. E [Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”. E Perspective | Can I get AstraZeneca now and Pfizer later? Why mixing and matching COVID vaccines could help solve many rollout problems. E RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects. E Should you mix and match COVID-19 vaccines? Scientists are seeking answers
Comentário no Twitter
The World Health Organization's chief scientist on Monday advised against people mixing and matching COVID-19 vaccines from different manufacturers, calling it a "dangerous trend" since there was little data available about the health impact. https://t.co/Oog6fWDSMz
— Reuters Health (@Reuters_Health) July 13, 2021
Debate Pró-Con | Deveríamos postergar a vacinação contra Covid-19 em crianças?
13 Jul, 2021 | 11:25hShould we delay covid-19 vaccination in children? – The BMJ
Comunicado de imprensa: Should we delay COVID-19 vaccination in children? – British Medical Journal
Comentário no Twitter
Covid-19 vaccines in adults have been remarkably effective. There is good reason to expect that the same will be true in children.
A group of authors discuss the pros and cons of vaccinating children against covid-19 https://t.co/TOEI67YPeH
— The BMJ (@bmj_latest) July 9, 2021
Casos extremamente raros de Guillain-Barré relatados com a vacina da Johnson & Johnson contra a Covid-19.
13 Jul, 2021 | 11:24hJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
Ver também: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR E F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Podcast | Uso de antibióticos.
13 Jul, 2021 | 11:16h#284 An Antibiotics Primer, with @IDdocAdi – The Curbsiders
Outro estudo randomizado avaliou a eficácia e a qualidade de vida no tratamento somente com antibióticos da apendicite aguda não complicada.
13 Jul, 2021 | 11:16hA Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link para o resumo – $ para o texto completo)
Relacionado: A Randomized trial comparing antibiotics with appendectomy for appendicitis E Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin E Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis E Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis E Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children E Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International
Comentário no Twitter
The debate continues!
Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from 🇮🇪
Recurrence within 1-year : 25% after AB
Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb
— Ville Sallinen (@villesallinen) July 11, 2021