Acesso livre
Acesso livre

Infectologia

Estudo randomizado | Antibioticoterapia por 7 dias é tão boa quanto por 14 dias para homens com infecção de trato urinário que estejam sem febre.

2 Ago, 2021 | 16:51h

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

Editorial: Shorter Courses of Antibiotics for Urinary Tract Infection in Men (gratuito por tempo limitado)

Comentário: Study Supports Shorter Antibiotic Course for Afebrile Men With UTI – MPR

 

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Relatório do CDC | Transmissão de Candida auris pan-resistente em instituições de cuidados em saúde.

2 Ago, 2021 | 16:46h

Notes from the Field: Transmission of Pan-Resistant and Echinocandin-Resistant Candida auris in Health Care Facilities ― Texas and the District of Columbia, January–April 2021 – CDC Morbidity and Mortality Weekly Report

Comentários:

CDC reports two outbreaks of pan-resistant Candida auris – CIDRAP

U.S. sees first cases of dangerous fungus resistant to all drugs in untreated people – STAT

Conteúdos relacionados:

Case reports: Multidrug-resistant Candida auris infections in critically ill Covid-19 patients

Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings

Global Epidemiology of Emerging Candida Auris (revisões e comentários sobre o tema)

The superbug Candida auris is giving rise to warnings — and big questions – STAT

Candida Auris – “A Mysterious Infection, Spanning the Globe in a Climate of Secrecy” (revisões e comentários sobre o tema)

 

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Revisão | Long Covid – Mecanismos, fatores de risco e tratamento.

27 Jul, 2021 | 10:35h

Long covid—mechanisms, risk factors, and management – The BMJ

 

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[Preprint] Covid-19: intervalo mais longo entre as doses da vacina da Pfizer aumenta a resposta imune.

27 Jul, 2021 | 10:34h

Comunicado de imprensa: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity – Newcastle University

Estudo original (preprint): Sustained T cell immunity, protection and boosting using extended dosing intervals of BNT162b2 mRNA vaccine

Comentários:

Commentary: Covid-19: Longer interval between Pfizer doses results in higher antibody levels, research finds – BMJ

Expert reaction to preprint from PITCH study looking at interval between two Pfizer vaccine doses, and antibody and T-cell responses – Science Media Centre

Conteúdo Relacionado:

Debate: Should we delay second vaccine doses to give one dose of the Covid-19 vaccine to more people? (vários textos sobre o tema)

Outro estudo mostra resposta imune aumentada com vacinação heteróloga Oxford-AstraZeneca/mRNA.

27 Jul, 2021 | 10:32h

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination – Nature Medicine

Comentário: A ‘mix and match’ approach to SARS-CoV-2 vaccination – Nature Medicine

Conteúdos Relacionados:

WHO warns against mixing and matching COVID vaccines.

Germany issues world’s strongest recommendation for mixing Covid-19 vaccines.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

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Opinião | O que realmente significa saúde pública? Lições da Covid-19.

27 Jul, 2021 | 10:31h

What does public health really mean? Lessons from covid-19 – The BMJ Opinion

 

Comentário no Twitter (fio – clique para saber mais)

 

Grandes grupos médicos dos Estados Unidos pedem que os empregadores imponham a vacinação contra Covid-19 aos trabalhadores da área da saúde.

27 Jul, 2021 | 10:30h

Major medical groups call for employers to mandate Covid-19 vaccines for health care workers – CNN

Documento original: Joint Statement in Support of COVID-19 Vaccine Mandates for All Workers in Health and Long-Term Care

 

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Avaliação da segurança da segunda dose de vacinas de mRNA contra COVID-19 em pacientes com reações alérgicas na primeira dose.

27 Jul, 2021 | 10:27h

Safety Evaluation of the Second Dose of Messenger RNA COVID-19 Vaccines in Patients With Immediate Reactions to the First Dose – JAMA Internal Medicine

Comentários:

Second COVID-19 mRNA vaccine dose found safe following allergic reactions to first dose – Massachusetts General Hospital

No anaphylaxis after second dose of mRNA COVID vaccine, study finds – CIDRAP

 

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[Preprint] Estudo observacional | Efetividade da vacina Oxford-AstraZeneca em idosos durante a transmissão da variante Gama do SARS-CoV-2 no Brasil – A efetividade ajustada foi de 77,9% para Covid-19 sintomática, 87,6% contra hospitalização e 93,6% contra morte.

27 Jul, 2021 | 10:26h

Effectiveness of the ChAdOx1 vaccine in the elderly during SARS-CoV-2 Gamma variant transmission in Brazil – medRxiv

 

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[Preprint] Estudo observacional | Efetividade da vacina CoronaVac em idosos durante a transmissão da variante Gama do SARS-CoV-2 no Brasil – A efetividade ajustada foi de 41,6% para Covid-19 sintomática, 59% contra hospitalização e 71,4% contra morte.

27 Jul, 2021 | 10:25h

Effectiveness of the CoronaVac vaccine in the elderly population during a Gamma variant-associated epidemic of COVID-19 in Brazil: A test-negative case-control study – medRxiv

 

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