Acesso livre
Acesso livre

Infectologia

Marcador sanguíneo (anticorpos neutralizantes) prediz quem irá desenvolver ‘breakthrough infection’ (infecção em indivíduos vacinados).

3 Ago, 2021 | 11:29h

A blood marker predicts who gets ‘breakthrough’ COVID – Nature

Conteúdos relacionados:

A correlate of protection for SARS-CoV-2 vaccines is urgently needed – “Recent studies suggest that neutralizing antibodies could serve as a correlate of protection for vaccines against SARS-CoV-2 in humans”.

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.

Covid-19 breakthrough infections in vaccinated health care workers.

Covid: especialistas afirmam que oxímetros de pulso não funcionam tão bem em pele mais escura.

3 Ago, 2021 | 11:28h

Covid: Pulse oxygen monitors work less well on darker skin, experts say – BBC

Conteúdos relacionados:

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias

“Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients

OMS: para combater a Covid, a lição é simples – ninguém está salvo até que todos estejam.

3 Ago, 2021 | 11:26h

To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe – The Guardian

 

Comentário no Twitter

 

OMS insiste para que os países aumentem os serviços para tratamento de hepatites.

3 Ago, 2021 | 11:19h

WHO Urges Countries to Increase Hepatitis Services – Health Policy Watch

Campanha OMS: World Hepatitis Day (28 de julho)

Novas diretrizes OMS:

Recommendations and guidance on hepatitis C virus self-testing – World Health Organization

Interim guidance for country validation of viral hepatitis elimination – World Health Organization

Prevalência, custos e consequências da urinálise pré-procedimento (procedimento frequentemente de pouca utilidade/valor) nos EUA.

3 Ago, 2021 | 11:15h

Prevalence, Costs, and Consequences of Low-Value Preprocedural Urinalyses in the US – JAMA Internal Medicine

Editorial: Moving Beyond Guidelines—Use of Value-Based Preoperative Testing (gratuito por tempo limitado)

Comentário: Preoperative screening urinalysis is widely used—but usually unnecessary, study finds – MedicalXpress

O estudo por trás da nova diretriz do CDC sobre uso de máscara mostra que pessoas vacinadas podem disseminar a variante Delta.

2 Ago, 2021 | 19:20h

Relatório do CDC: Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021 – Centers for Disease Control and Prevention

Comentários:

The Study Behind CDC’s Mask Guidance Found Vaccinated People Can Spread Delta Variant – NPR

What Delta has changed in the Covid pandemic — and what it hasn’t – STAT

 

Comentário no Twitter (fio – clique para saber mais)

 

Recomendações da ACOG e da SMFM para a vacinação contra COVID-19 em gestantes – “ACOG encoraja seus membros a recomendar enfaticamente a vacinação para suas pacientes.”

2 Ago, 2021 | 19:18h

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM)

Leituras adicionais:

Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care

COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians

Comentários:

Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press

Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes

 

Comentário no Twitter

 

Opinião | Gestantes devem se vacinar contra COVID? As evidências mostram que é seguro e eficaz.

2 Ago, 2021 | 19:16h

Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective – The Conversation

Diretriz | Abordagem clínica de adultos com COVID-19 fora da UTI.

2 Ago, 2021 | 19:13h

Clinical Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) – Infectious Diseases and Therapy

O que todo intensivista deveria saber sobre o tocilizumabe.

2 Ago, 2021 | 19:11h

What every intensivist should know about Tocilizumab – Critical Care

Conteúdos relacionados:

Tocilizumab in COVID-19 therapy: who benefits, and how?

A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.

M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.

M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

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