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Acesso livre

Infectologia Pediátrica

[Preprint] Transmissão de SARS-CoV-2 por aerossol em escolas: efetividade teórica de diferentes intervenções – “Intervenções combinadas (i.e., ventilação natural, máscaras e filtração HEPA) foram as mais eficazes (redução ≥ 30 vezes)”.

23 Ago, 2021 | 13:12h

SARS-CoV-2 aerosol transmission in schools: the effectiveness of different interventions – medRxiv

Conteúdo relacionado: The right way to protect our children and return to in-person learning – CNN

 

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Opinião | Vá em frente. Vacine as crianças. O risco dessa vacinação nunca será zero, mas a alternativa é muito pior.

18 Ago, 2021 | 12:48h

Go Ahead. Vaccinate the Kids. – The Atlantic

Opinião | “O medo da Covid-19 em crianças está indo além do que os dados mostram.”

16 Ago, 2021 | 11:59h

Fear of COVID-19 in Kids Is Getting Ahead of the Data – The Atlantic

Doença de Kawasaki e síndrome inflamatória multissistêmica em crianças: uma visão geral e comparação.

13 Ago, 2021 | 12:27h

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison – American Family Physician

Conteúdos relacionados:

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Estudo randomizado | Avaliação da vacina de mRNA da Moderna em adolescentes.

12 Ago, 2021 | 12:30h

Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents – New England Journal of Medicine

Conteúdos relacionados:

Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%).

 

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Revisão sobre COVID-19: manifestações abdominais em adultos e síndrome inflamatória multissistêmica em crianças.

6 Ago, 2021 | 11:47h

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children – Clinical Imaging

Diretriz PIDS-IDSA sobre diagnóstico e tratamento da osteomielite hematogênica aguda em pediatria.

6 Ago, 2021 | 11:40h

Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics – Journal of the Pediatric Infectious Diseases Society

Comunicado de imprensa: New PIDS-IDSA guideline on bone infections in children addresses key diagnostic and treatment questions – Pediatric Infectious Diseases Society

Comentário sobre as últimas diretrizes da AAP sobre o neonato febril.

5 Ago, 2021 | 11:31h

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

Diretriz original:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Conteúdos relacionados:

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

Duração da doença e perfil de sintomas em ciranças sintomáticas testadas para SARS-CoV-2 – “Apenas 25 (1,8%) de 1.379 crianças apresentaram sintomas por 56 dias ou mais.”

4 Ago, 2021 | 12:41h

Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2 – The Lancet Child & Adolescent Health

Comentário convidado: Citizen science and biomedical research (necessário cadastro gratuito)

Comentários:

Expert reaction to study looking at long-lasting symptoms from COVID-19 in children – Science Media Centre

Long Covid uncommon in children, analysis finds – King’s College London

Study finds long-term Covid symptoms rare in school-age children – The Guardian

Most children with Covid-19 recover within a week, but a small percentage have long-term symptoms, a study says. – The New York Times

Conteúdos relacionados:

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Cohort study: Risk factors for long covid in previously hospitalized children.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

Comentário no Twitter

 

Diretriz AAP sobre apoio às necessidades de saúde emocional e comportamental de crianças, adolescentes e famílias durante a pandemia de COVID-19.

4 Ago, 2021 | 12:38h

Interim Guidance on Supporting the Emotional and Behavioral Health Needs of Children, Adolescents, and Families During the COVID-19 Pandemic – American Academy of Pediatrics

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