Imunologia Pediátrica

Análise de uma intervenção em serviços de emergência médica visando a reduzir os erros de dosagem de epinefrina em bebês.

21 Abr, 2022 | 11:28h

Analysis of an Intervention for Emergency Medical Services Personnel to Reduce Epinephrine Dosing Errors in Infants – JAMA Network Open

 

Comentário no Twitter

In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

 

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Estudo de coorte | Preditores de doença grave em crianças com síndrome inflamatória multissistêmica após infecção pelo SARS-CoV-2.

14 Abr, 2022 | 16:58h

Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: a multicentre cohort study – Canadian Medical Association Journal

Comunicado de imprensa: Children older than 5 at higher risk of COVID-19-related multisystem inflammatory syndrome – Canadian Medical Association Journal

Comentário: Older Kids More Vulnerable to MIS-C: Study – HealthDay

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Estudo de coorte | Desfechos de curto prazo da monoterapia com corticosteroide na síndrome inflamatória multissistêmica em crianças.

31 Mar, 2022 | 13:40h

Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

 

Comentário no Twitter

In this study, corticosteroid monotherapy successfully treated a subset of patients with mild multisystem inflammatory syndrome in children. https://t.co/fuhHeBSaRp

— JAMA Pediatrics (@JAMAPediatrics) March 28, 2022

 

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Estudo de coorte | Exposição pré-natal ocupacional a desinfetante está associada a risco aumentado de alergias na infância.

31 Mar, 2022 | 12:28h

Prenatal occupational disinfectant exposure and childhood allergies: the Japan Environment and Children’s study – Occupational & Environmental Medicine

Comentário: Disinfectant use by pregnant women may increase risk for asthma and eczema in children – BMJ/News Medical

 

Comentário no Twitter

Disinfectant use during pregnancy linked to childhood asthma and eczema, suggests @OEM_BMJ research https://t.co/90JYoTFHpo pic.twitter.com/zlqouZWQSM

— BMJ (@bmj_company) March 29, 2022

 

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Prevalência de rotulagem da alergia à penicilina variou de 0,9% a 10,2% entre práticas em uma ampla coorte pediátrica, levantando questões sobre a validade desses rótulos e o uso desnecessário de antibióticos de segunda linha que pode se seguir.

29 Mar, 2022 | 14:12h

Factors Associated With Penicillin Allergy Labels in Electronic Health Records of Children in 2 Large US Pediatric Primary Care Networks – JAMA Network Open

Conteúdos relacionados: A pharmacist-led penicillin allergy assessment program can delabel many “penicillin allergic” patients through allergy histories and penicillin skin testing. The program was associated with reduced use of high Clostridioides difficile infection–risk antibiotics.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Consensus Recommendations: Management of a Surgical Patient with a Label of Penicillin Allergy

Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

Comentário no Twitter

In this cohort study of more than 330,000 children, less than 5% were labeled with penicillin allergy with wide variation across practices, with 8% of those labeled despite not receiving any penicillin prescription. https://t.co/kvXcm1RKRd

— JAMA Network Open (@JAMANetworkOpen) March 15, 2022

 

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Ampla experiência multicêntrica francesa | Síndrome da enterocolite induzida pela proteína alimentar.

25 Mar, 2022 | 15:23h

Food protein-induced enterocolitis syndrome: A large French multicentric experience – Clinical and Translational Allergy

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Revisão sistemática | Estratégias para uso tópico de corticosteroides em crianças e adultos com eczema.

22 Mar, 2022 | 11:33h

Strategies for using topical corticosteroids in children and adults with eczema – Cochrane Library

Resumo: What is the best way to use topical corticosteroids to treat people with eczema? – Cochrane Library

 

Comentário no Twitter

What is the best way to use topical #corticosteroids to treat people with #eczema?
"Generally, stronger topical corticosteroids are probably more effective than weaker preparations". https://t.co/iaH6fzyXL4

Read the latest evidence from @CochraneSkin @CebdNottm pic.twitter.com/f01BO2FyDs

— Cochrane UK (@CochraneUK) March 17, 2022

 

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Coorte retrospectiva | Asma em crianças e adolescentes não está associada a risco aumentado de infecção por SARS-CoV-2.

15 Mar, 2022 | 13:17h

Asthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents – Pediatrics

Comentário: Kids with asthma not at higher risk of COVID-19, study finds – CIDRAP

Conteúdos relacionados:

We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.

M-A: Asthma does not increase the risk of infection, hospitalization, ICU admission, and mortality from COVID-19

Systematic review: No evidence that patients with asthma are at increased risk of COVID-19 diagnosis, hospitalization or death

Asthma in COVID-19 hospitalizations: An overestimated risk factor?

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Estudo randomizado aberto | Azitromicina para asma mal controlada em crianças.

15 Mar, 2022 | 13:09h

Azithromycin for Poorly Controlled Asthma in Children: A randomized controlled trial – CHEST (link para o resumo – $ para o texto completo)

Comentário: Adding azithromycin to standard care improves asthma control, exacerbations in children – Healio

Conteúdo relacionado: Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma

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Revisão sistemática | Efeitos da educação sobre asma nos desfechos de saúde em crianças.

25 Fev, 2022 | 14:15h

Effect of asthma education on health outcomes in children: a systematic review – Archives of Disease in Childhood

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