Hematologia
Estudo randomizado | Ruxolitinibe para doença do enxerto versus hospedeiro refratária a glicocorticoide.
16 Jul, 2021 | 09:45hEstudo de coorte | Aumento no risco de longo prazo para o desenvolvimento de anemia após cirurgia bariátrica – Em comparação com o grupo-controle, a incidência de anemia foi aumentada no grupo com by-pass gástrico (HR 5,05), no grupo com gastroplastia vertical (HR 2,67) e no grupo com banda gástrica (HR 2,76).
15 Jul, 2021 | 10:28hLong-term risk of anaemia after bariatric surgery: results from the Swedish Obese Subjects study – The Lancet Diabetes & Endocrinology (link para o resumo – $ para o texto completo)
Algoritmos de tratamento da leucemia promielocítica aguda.
15 Jul, 2021 | 10:17hAcute promyelocytic leukemia current treatment algorithms – Blood Cancer Journal
[Preprint] Heparina para pacientes com Covid-19 moderada – “Em pacientes com Covid-19 moderada e D-dímero elevado, a terapia com heparina não reduziu significativamente o desfecho primário, mas reduziu as chances de morte em 28 dias de doença.”
12 Jul, 2021 | 11:41hHeparin for Moderately Ill Patients with Covid-19 – medRxiv
Relacionado: RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk. E [Preprint] Practice Changing RCT: Therapeutic-dose anticoagulation with heparin (LMWH or unfractionated heparin) improves outcomes in non-critically ill patients with Covid-19 – the superiority of therapeutic-dose anticoagulation was seen in both high and low D-dimer groups. E [Preprint] RCT: Full-dose/therapeutic anticoagulation provides no benefit in critically ill patients with Covid-19
Comentário no Twitter (fio – clique para saber mais)
🚨Final results of the RAPID trial now pub'd @medrxivpreprint 🚨 RAPID was an open-label trial that randomly assigned hospitalized ward patients with COVID-19 and elevated D-dimer levels to therapeutic or prophylactic heparin. 🧵 1/10 https://t.co/oxiyXQAPeK pic.twitter.com/V2GtruEyM2
— Michelle Sholzberg (@sholzberg) July 9, 2021
Podcast | Sangramento menstrual intenso, anticoagulação e coagulopatia em pacientes que menstruam.
9 Jul, 2021 | 15:46hSérie de casos | Plasmaférese em 3 pacientes com trombocitopenia trombótica imune induzida por vacina.
8 Jul, 2021 | 09:56h
Comentário no Twitter
Three patients with severe manifestations of VITT after #COVID19 vaccination had poor response to initial therapy with anticoagulants and intravenous immune globulin. Their condition improved after therapeutic plasma exchange was initiated.
— NEJM (@NEJM) July 7, 2021
Perspectiva | Pessoas com problemas imunológicos deveriam tomar uma 3ª dose de vacina?
8 Jul, 2021 | 09:51hShould People With Immune Problems Get Third Vaccine Doses? – The New York Times (poucos artigos gratuitos por mês)
Relacionado: [Preprint] 3rd AstraZeneca shot gives strong immunity. E Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.
Comentário sobre estudo | Neutropenia febril – Procalcitonina vs. escore MASCC.
8 Jul, 2021 | 09:45hFebrile Neutropenia – Procalcitonin vs MASCC Score – Journal Feed
Diretriz sobre a abordagem perioperatória de pacientes com anemia falciforme.
8 Jul, 2021 | 09:36hGuideline on the peri-operative management of patients with sickle cell disease – Anaesthesia