Hematologia

M-A | Eficácia das vacinas contra Covid-19 em pacientes imunocomprometidos.

8 Mar, 2022 | 16:16h

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis – The BMJ

Comunicado de imprensa: Study suggests additional covid-19 vaccine doses for immunocompromised patients – BMJ Newsroom

Conteúdos relacionados: Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review.

Comentário no Twitter

NEW RESEARCH: Additional doses of covid-19 vaccine are recommended for immunocompromised patients, especially for organ transplant recipients who are least able to make antibodies to fight off coronavirus, suggests new research https://t.co/l2IWfSb0zd @sundar__raghav

— The BMJ (@bmj_latest) March 3, 2022

Diretriz | Tratamento da infecção por Clostridioides difficile em receptores de transplante de células hematopoiéticas.

3 Mar, 2022 | 15:47h

American Society for Transplantation and Cellular Therapy Series: #5 – Management of Clostridioides difficile infection in hematopoietic cell transplant recipients – Transplantation and Cellular Therapy

Ver outros artigos da série:

American Society of Transplantation and Cellular Therapy Series, 1: Enterobacterales Infection Prevention and Management after Hematopoietic Cell Transplantation

American Society of Transplantation and Cellular Therapy Series, 2: Management and Prevention of Aspergillosis in Hematopoietic Cell Transplantation Recipients

American Society for Transplantation and Cellular Therapy Series: #3—Prevention of Cytomegalovirus Infection and Disease After Hematopoietic Cell Transplantation

American Society for Transplantation and Cellular Therapy Series: #4 – Cytomegalovirus treatment and management of resistant or refractory infections after hematopoietic cell transplantation

Revisão JACC | Anticoagulação em pacientes com COVID-19.

2 Mar, 2022 | 11:42h

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Comentário: Review of Anticoagulation in Patients With COVID-19: Key Points – American College of Cardiology

Diretrizes clínicas SEOM para profilaxia de doenças infecciosas em pacientes oncológicos.

2 Mar, 2022 | 11:35h

SEOM clinical guidelines for the prophylaxis of infectious diseases in cancer patients – Clinical and Translational Oncology

Dois amplos estudos de base populacional mostram um risco ligeiramente aumentado de eventos trombóticos após vacinação contra COVID-19 com a vacina da AstraZeneca.

24 Fev, 2022 | 15:47h

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England – PLOS Medicine

Ver também: First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales – PLOS Medicine

Comentários:

Two studies find only small elevated risk of blood clots following AstraZeneca COVID-19 vaccination – PLOS

Two Large Studies Affirm Rare Thrombosis Risk With ChAdOx1 COVID-19 Vax – TCTMD

Revisão | Tromboembolismo venoso associado a câncer.

22 Fev, 2022 | 14:37h

Cancer-associated venous thromboembolism – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Cancer-associated venous thromboembolism – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Conteúdos relacionados:

NCCN Guideline: Cancer-Associated Venous Thromboembolic Disease.

ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer

Review: venous and arterial thromboembolism in patients with cancer.

Systematic Review: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness?

M-A: Extended thromboprophylaxis after hospital discharge for medically ill patients with cancer – Extended thromboprophylaxis is not associated with a reduced rate of venous thromboembolic events and is associated with increased risk of hemorrhage

Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy

Isatuximabe com pomalidomida e baixa dose de dexametasona vs. pomalidomida e baixa dose de dexametasona em pacientes com mieloma múltiplo refratário e recidivante (ICARIA-MM): análise do seguimento de um estudo randomizado de fase 3.

22 Fev, 2022 | 14:15h

Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): follow-up analysis of a randomised, phase 3 study – The Lancet Oncology (link para o resumo – $ para o texto completo)

Revisão | Resposta a doses adicionais de vacinas contra COVID-19 em pessoas imunocomprometidas.

17 Fev, 2022 | 14:43h

Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review – The Lancet Global Health

Comentário no Twitter

A review of the 23 studies of Covid vaccination for immunocompromised people indicates the level of responders varies with conditions. Even additional doses may not provide sufficient protection for some, requiring additional measureshttps://t.co/BjaKrJUAbO @LancetGH pic.twitter.com/EYVWAX23Ig

— Eric Topol (@EricTopol) February 15, 2022

Estudo prospectivo de diagnóstico e tratamento | Diagnóstico de trombose venosa profunda com D-dímero ajustado para probabilidade clínica.

17 Fev, 2022 | 14:23h

Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study – The BMJ

Uma ampla coorte de pacientes com síndrome nefrótica mostrou que o risco de tromboembolismo arterial (HR = 3,11), tromboembolismo venoso (HR = 7,11) e sangramento (HR = 4,02) foi bastante aumentado após ajuste dos elementos confundidores.

15 Fev, 2022 | 11:27h

Risk of arterial thromboembolism, venous thromboembolism, and bleeding in patients with nephrotic syndrome: A population-based cohort study – American Journal of Medicine (link para o resumo – $ para o texto completo)