Hematologia Geral

Consenso ESC | Terapias antitrombóticas nas doenças arteriais aórticas e periféricas em 2021.

2 Ago, 2021 | 16:44h

Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy – European Heart Journal

Pontos principais a lembrar: ESC Consensus on Antithrombotic Therapies in Aortic and Peripheral Artery Diseases – American College of Cardiology

Comentário no Twitter

The new consensus document from the ESC working group on aorta and peripheral vascular diseases on best antithrombotic strategies!#aorta #antithrombotic #therapy #EHJ #cardiotwitter @escardio @ESC_Journals https://t.co/ga17wxKDGi pic.twitter.com/CSSgE5TFdX

— EHJ Editor-in-Chief (@ehj_ed) July 23, 2021

Revisão | Complicações hemostáticas e trombóticas da doença hepática.

23 Jul, 2021 | 10:01h

The Hemostatic and Thrombotic Complications of Liver Disease – European Journal of Haematology

Estudo de coorte | Anemia falciforme e desfechos de COVID-19 – “Nossa análise estima um aumento de 4 vezes no risco de hospitalização por COVID-19 e de 2,6 vezes no risco de morte relacionada a COVID-19 em pacientes com anemia falciforme.”

21 Jul, 2021 | 09:55h

Sickle Cell Disorders and Severe COVID-19 Outcomes: A Cohort Study – Annals of Internal Medicine

Diretriz da OMS para manejo clínico da síndrome de trombose com trombocitopenia após vacinação contra coronavírus (COVID-19).

20 Jul, 2021 | 10:58h

Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19) – World Health Organization

Diretriz relacionada: AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.” E ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia

Opinião do especialista | Válvulas bioprotéticas e fibrilação atrial: anticoagulantes diretos ou warfarina – Até que dados conclusivos sobre pacientes com doença cardíaca reumática e aqueles com válvulas mecânicas estejam disponíveis, o uso de DOAC não é indicado.

20 Jul, 2021 | 10:43h

Bioprosthetic valves and atrial fibrillation: Direct anticoagulants or warfarin – The Journal of Thoracic and Cardiovascular Surgery

Estudo de coorte | Aumento no risco de longo prazo para o desenvolvimento de anemia após cirurgia bariátrica – Em comparação com o grupo-controle, a incidência de anemia foi aumentada no grupo com by-pass gástrico (HR 5,05), no grupo com gastroplastia vertical (HR 2,67) e no grupo com banda gástrica (HR 2,76).

15 Jul, 2021 | 10:28h

Long-term risk of anaemia after bariatric surgery: results from the Swedish Obese Subjects study – The Lancet Diabetes & Endocrinology (link para o resumo – $ para o texto completo)

[Preprint] Heparina para pacientes com Covid-19 moderada – “Em pacientes com Covid-19 moderada e D-dímero elevado, a terapia com heparina não reduziu significativamente o desfecho primário, mas reduziu as chances de morte em 28 dias de doença.”

12 Jul, 2021 | 11:41h

Heparin for Moderately Ill Patients with Covid-19 – medRxiv

Relacionado: RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk. E [Preprint] Practice Changing RCT: Therapeutic-dose anticoagulation with heparin (LMWH or unfractionated heparin) improves outcomes in non-critically ill patients with Covid-19 – the superiority of therapeutic-dose anticoagulation was seen in both high and low D-dimer groups. E [Preprint] RCT: Full-dose/therapeutic anticoagulation provides no benefit in critically ill patients with Covid-19

Comentário no Twitter (fio – clique para saber mais)

🚨Final results of the RAPID trial now pub'd @medrxivpreprint 🚨 RAPID was an open-label trial that randomly assigned hospitalized ward patients with COVID-19 and elevated D-dimer levels to therapeutic or prophylactic heparin. 🧵 1/10 https://t.co/oxiyXQAPeK pic.twitter.com/V2GtruEyM2

— Michelle Sholzberg (@sholzberg) July 9, 2021

Podcast | Sangramento menstrual intenso, anticoagulação e coagulopatia em pacientes que menstruam.

9 Jul, 2021 | 15:46h

#280 Heavy Menstrual Bleeding, Anticoagulation & Coagulopathy in Menstruating Patients – The Curbsiders

Série de casos | Plasmaférese em 3 pacientes com trombocitopenia trombótica imune induzida por vacina.

8 Jul, 2021 | 09:56h

Therapeutic Plasma Exchange in Vaccine-Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine

Comentário no Twitter

Three patients with severe manifestations of VITT after #COVID19 vaccination had poor response to initial therapy with anticoagulants and intravenous immune globulin. Their condition improved after therapeutic plasma exchange was initiated.

— NEJM (@NEJM) July 7, 2021

Diretriz sobre a abordagem perioperatória de pacientes com anemia falciforme.

8 Jul, 2021 | 09:36h

Guideline on the peri-operative management of patients with sickle cell disease – Anaesthesia