Hematologia Geral
Revisão | Trombocitopenia trombótica imune induzida por vacina.
16 Nov, 2021 | 12:46hVaccine-induced immune thrombotic thrombocytopenia – The Lancet Haematology
Conteúdos relacionados:
Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.
Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.
Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (vários artigos e fontes sobre o tema)
Comentário no Twitter
NEW Viewpoint by @Erik_Klok_MD, @MPaiMD, Menno Huisman & @ProfMakris discussing the epidemiology, pathophysiology, and optimal diagnostic and therapeutic management of vaccine-induced immune thrombotic thrombocytopenia #VITT #COVID19Vaccine https://t.co/FI4NynwzEn pic.twitter.com/9PbjaioA2T
— The Lancet Haematology (@TheLancetHaem) November 12, 2021
#AHA21 – [Ainda não publicado] | Um estudo pequeno e randomizado mostrou que interromper o ticagrelor apenas 2-3 dias antes da cirurgia de by-pass pode ser seguro.
15 Nov, 2021 | 13:46hComunicado de imprensa: Ticaglelor may be stopped Time from stopping blood thinner to bypass surgery may be shortened for select patients – American Heart Association
Comentário: RAPID CABG: No Penalty to Early Surgery for ACS After Stopping Ticagrelor – TCTMD
Estudo randomizado | Em pacientes com doença renal crônica e anemia em tratamento dialítico, a medicação oral daprodustate foi não inferior a darbepoetina alfa em aumentar os níveis de hemoglobina e também em relação aos desfechos cardiovasculares.
8 Nov, 2021 | 12:33hDaprodustat for the Treatment of Anemia in Patients Undergoing Dialysis – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comunicado de imprensa: Oral pill as safe, efficacious as conventional treatment for anemia in patients with kidney disease – Brigham and Women’s Hospital
Comentário no Twitter
In this phase 3 clinical trial, daprodustat was effective as a treatment for anemia in patients with CKD who were undergoing maintenance hemodialysis or peritoneal dialysis. #KidneyWk https://t.co/ykzSsUlJci pic.twitter.com/0zdlMyOlTf
— NEJM (@NEJM) November 5, 2021
Estudo randomizado | Em pacientes com doença renal crônica e anemia que não estão sendo submetidos a diálise, a medicação oral daprodustate foi não inferior a darbepoetina alfa em aumentar os níveis de hemoglobina e também em relação aos desfechos cardiovasculares.
8 Nov, 2021 | 12:32hDaprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comunicado de imprensa: Oral pill as safe, efficacious as conventional treatment for anemia in patients with kidney disease – Brigham and Women’s Hospital
Comentário no Twitter
In this trial, daprodustat was as effective as darbepoetin alfa in increasing and maintaining hemoglobin levels in patients with CKD and anemia who were not receiving dialysis. #KidneyWk https://t.co/D2unQFLH6T pic.twitter.com/KqdLfVlkuD
— NEJM (@NEJM) November 5, 2021
Diretriz ASH emite recomendação condicional contra o uso rotineiro de anticoagulação profilática ambulatorial em pacientes com COVID-19 depois da alta hospitalar.
4 Nov, 2021 | 12:03hAnticoagulantes e agentes para diabetes estão entre as causas mais frequentes de entrada nos departamentos de emergência atribuídas a danos farmacológicos.
27 Out, 2021 | 12:25hUS Emergency Department Visits Attributed to Medication Harms, 2017-2019 – JAMA (link para o resumo – $ para o texto completo)
Comentários:
Number of emergency room visits for medication harms increases with age – MedicalResearch.com
Blood thinners, diabetes meds among top causes of drug-related ER visits – UPI
Diretriz | Estratégias de transfusão de sangue no sangramento de adultos criticamente doentes.
25 Out, 2021 | 12:58h
Comentário no Twitter
Transfusion strategies in bleeding critically ill adults current evidence/research areas from @ESICM clinical practice guideline
🩸massive bleedings
🩸non‑massive bleedings
🩸tranexamic acid in traumatic/non‑traumatic hemorrhages
Open #FOAMcc on @yourICM
🖇️https://t.co/LtEzrLcaM5 pic.twitter.com/Po7eFYpdeW— Intens Care Med (@yourICM) October 22, 2021
Diretriz NCCN | Doença tromboembólica venosa associada a câncer.
21 Out, 2021 | 11:25hConteúdos relacionados:
ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer
Review: venous and arterial thromboembolism in patients with cancer.
Resumo de Política da OMS | A necessidade urgente de se implementar o manejo de sangue do paciente.
20 Out, 2021 | 11:58hThe urgent need to implement patient blood management: policy brief – World Health Organization