Gestão de Antimicrobianos

Estudo randomizado | Ceftolozano/tazobactam com metronidazol vs. meropeném em pacientes com infecções intra-abdominais complicadas.

22 Ago, 2022 | 16:26h

A Phase 3, Multicenter, Double-blind, Randomized Clinical Trial to Evaluate the Efficacy and Safety of Ceftolozane/Tazobactam Plus Metronidazole Versus Meropenem in Chinese Participants With Complicated Intra-abdominal Infections – International Journal of Infectious Diseases

 

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Relatório clínico atualizado da AAP | Uso de fluoroquinolonas sistêmicas e tópicas.

22 Ago, 2022 | 16:01h

The Use of Systemic and Topical Fluoroquinolones – Pediatrics

 

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Diretriz NICE | Infecção de trato urinário em menores de 16 anos: diagnóstico e tratamento.

16 Ago, 2022 | 13:09h

Urinary tract infection in under 16s: diagnosis and management – National Institute for Health and Care Excellence

 

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M-A | Intervenções para reduzir infecções em pacientes com malignidades hematológicas.

16 Ago, 2022 | 12:39h

Interventions to reduce infections in patients with hematological malignancies: a systematic review and meta-analysis – Blood Advances

Comentário: Prophylactic Immunoglobulin, Vaccinations May Reduce Infections in Hematologic Malignancies – AJMC

 

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Diferenças idade-sexo no impacto global de infecções de trato respiratório inferior e fatores de risco, 1990-2019: resultados do Global Burden of Disease Study 2019.

15 Ago, 2022 | 13:35h

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 – The Lancet Infectious Diseases

Comentário convidado: Trends in the global burden of lower respiratory infections: the knowns and the unknowns – The Lancet Infectious Diseases

 

Comentário no Twitter (fio – clique para saber mais)

New Research: Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 https://t.co/rhV7lRaZvc (1/2) pic.twitter.com/I0INjaMh4I

— The Lancet Infectious Diseases (@TheLancetInfDis) August 12, 2022

 

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M-A | Acurácia diagnóstica de testes de antígeno urinário para pneumonia pneumocócica entre pacientes com pneumonia e insuficiência respiratória aguda.

15 Ago, 2022 | 13:26h

Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia: a systematic review and meta-analysis – BMJ Open

 

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Podcast | Dicas sobre meningites.

15 Ago, 2022 | 13:25h

#346 Meningitis – The Curbsiders

 

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Estudo randomizado | Solução inalatória de tobramicina é efetiva em adultos com bronquiectasia e infecção por Pseudomonas aeruginosa.

12 Ago, 2022 | 18:08h

A Double-blind Randomized Placebo-controlled Phase-3 Trial of Tobramycin Inhalation Solution in Adults with Bronchiectasis with Pseudomonas aeruginosa Infection – CHEST

Comentário: Tobramycin Tames Infection in Bronchiectasis – Medscape (necessário cadastro gratuito)

Estudo relacionado: Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax

 

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Estudo de coorte retrospectiva | Em pacientes com infecção de prótese articular recorrente após tentativa de erradicação cirúrgica, a supressão com antibioticoterapia de longo prazo pode ser uma estratégia razoável em pacientes que não têm ou que se recusam a mais opções cirúrgicas de tratamento.

12 Ago, 2022 | 17:19h

Predictors of Success with Chronic Antibiotic Suppression for Prosthetic Joint Infections – The Journal of Arthroplasty (link para o resumo – $ para o texto completo)

Comentário: Chronic antibiotic suppression may successfully treat periprosthetic joint infections – Healio (necessário cadastro gratuito)

 

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Sinopse de diretriz | Tratamento da infecção por Clostridioides difficile.

10 Ago, 2022 | 14:38h

Treatment of Clostridioides difficile Infection – JAMA (gratuito por tempo limitado)

Diretriz original: ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections – American Journal of Gastroenterology

Diretrizes relacionadas:

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults – Clinical Infectious Diseases

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases – International Journal of Infectious Diseases

Clostridioides difficile infection: antimicrobial prescribing – National Institute for Health and Care Excellence

Japanese Clinical Practice Guidelines for Management of Clostridioides (Clostridium) difficile infection – Journal of Infection and Chemotherapy

 

Comentário no Twitter

A summary of @AmCollegeGastro’s 2021 guidelines on treatment of Clostridioides difficile infection. https://t.co/QzrMa71ttu

— JAMA (@JAMA_current) August 8, 2022

 

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