Gestão de Antimicrobianos

Estudo de coorte | Variações socioeconômicas determinam a apresentação clínica, a etiologia e o desfecho da endocardite infecciosa.

31 Mar, 2022 | 12:56h

Socio-Economic Variations Determine the Clinical Presentation, Aetiology and Outcome of Infective Endocarditis: a Prospective Cohort Study from the ESC-EORP EURO-ENDO (European Infective Endocarditis) Registry – European Heart Journal – Quality of Care and Clinical Outcomes

 

Comentário no Twitter

Infective #endocarditis – do socio-economic factors impact presentation and prognosis? Unfortunately yes, according to data from EURO-ENDO Registry: https://t.co/JdKM5igihR #CVD #EHJQCCO @cpgale3 @diogoasantosfer pic.twitter.com/pkclJdRsdU

— European Society of Cardiology Journals (@ESC_Journals) March 28, 2022

 

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Estudo antes-e-depois | Efetividade da implementação de cuidados preventivos com o cateter urinário em pacientes com fratura de quadril.

29 Mar, 2022 | 14:44h

Effectiveness of implementing a preventive urinary catheter care bundle in hip fracture patients – Journal of Infection Prevention

Comunicado de imprensa: Catheter infections went down after more preventive efforts – University of Gothenburg

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Revisão | Antibioticoterapia curta e oral para infecção do pé diabético.

29 Mar, 2022 | 14:41h

Short and oral antimicrobial therapy for diabetic foot infection: a narrative review of current knowledge – Journal of Bone and Joint Infection

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Prevalência de rotulagem da alergia à penicilina variou de 0,9% a 10,2% entre práticas em uma ampla coorte pediátrica, levantando questões sobre a validade desses rótulos e o uso desnecessário de antibióticos de segunda linha que pode se seguir.

29 Mar, 2022 | 14:12h

Factors Associated With Penicillin Allergy Labels in Electronic Health Records of Children in 2 Large US Pediatric Primary Care Networks – JAMA Network Open

Conteúdos relacionados: A pharmacist-led penicillin allergy assessment program can delabel many “penicillin allergic” patients through allergy histories and penicillin skin testing. The program was associated with reduced use of high Clostridioides difficile infection–risk antibiotics.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Consensus Recommendations: Management of a Surgical Patient with a Label of Penicillin Allergy

Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

Comentário no Twitter

In this cohort study of more than 330,000 children, less than 5% were labeled with penicillin allergy with wide variation across practices, with 8% of those labeled despite not receiving any penicillin prescription. https://t.co/kvXcm1RKRd

— JAMA Network Open (@JAMANetworkOpen) March 15, 2022

 

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M-A | Mortalidade da bacteriemia por Staphylococcus aureus.

25 Mar, 2022 | 15:31h

Staphylococcus aureus bacteremia mortality: A systematic review and meta-analysis – Clinical Microbiology and Infection

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M-A | Rastreamento da tuberculose entre pacientes HIV-positivos internados.

25 Mar, 2022 | 15:30h

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis – The Lancet HIV

 

Comentário no Twitter

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis https://t.co/DqTUr2JxHy In setting where TB prevalence is > 10%, WHO now strongly recommends molecular rapid diagnostic testing in all medical inpatient PWH.

— Carlos del Rio (@CarlosdelRio7) March 24, 2022

 

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Estudo randomizado | Tratamento com dose única de anfotericina B lipossomal para meningite por criptococo.

25 Mar, 2022 | 15:01h

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Cryptococcal meningitis is a major complication of HIV infection. Single-dose liposomal amphotericin B combined with flucytosine and fluconazole was noninferior to the WHO-recommended treatment and was associated with fewer adverse events. https://t.co/cg9DqSDhyN pic.twitter.com/SrKx4tDaph

— NEJM (@NEJM) March 23, 2022

 

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OMS lança diretrizes de tratamento clínico para influenza.

24 Mar, 2022 | 12:36h

Comunicado de imprensa: WHO releases clinical management guidelines for influenza – World Health Organization

Relatório original: Guidelines for the clinical management of severe illness from influenza virus infections – World Health Organization

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Incidência de complicações oculares em pacientes com candidíase disseminada e implicações para a prática de exames oculares de rotina.

24 Mar, 2022 | 11:58h

The Incidence of Ocular Complications in Candidemic Patients and Implications for the Practice of Routine Eye Exams – Open Forum Infectious Diseases

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Prevenção e tratamento do resfriado comum: quais são as evidências?

23 Mar, 2022 | 11:58h

Preventing and treating the common cold: what’s the evidence? – Evidently Cochrane

 

Comentário no Twitter

Preventing & treating the #CommonCold: what’s the evidence? https://t.co/kWHTwX1spb

Dr Lynda Ware looks at 14 possible interventions, including:

☀️ vitamin supplements,
💊 medicines,
🍯 home & herbal remedies
💉 vaccines

Might anything help & what are the possible risks? pic.twitter.com/ehpqEX8gwp

— Cochrane UK (@CochraneUK) March 21, 2022

 

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