Gastroenterologia

Estudo mostra que os níveis de aminotransferase são frequentemente normais em pacientes com cirrose relacionada ao uso do álcool e têm pouca correlação com complicações ou morte.

4 Fev, 2022 | 17:10h

Normal or Near Normal Aminotransferase Levels in Patients with Alcoholic Cirrhosis – American Journal of Medical Sciences (link para o resumo – $ para o texto completo)

Comentário: Physicians over-relying on a commonly used laboratory test can miss liver cirrhosis – Medical University of South Carolina

Revisão | Malignidades peritoneais primária e metastática.

4 Fev, 2022 | 15:51h

Primary and metastatic peritoneal surface malignancies – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Primary and metastatic peritoneal surface malignancies – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Comentário no Twitter

Treatment modalities for #peritoneal surface malignancies can be combined or used sequentially according to underlying #tumour type, disease extent and patients' condition and preference.https://t.co/cIkVAJRSaj pic.twitter.com/PUP1BtoTxE

— Nature Reviews Disease Primers (@DiseasePrimers) December 21, 2021

Estudo randomizado | 2 L de polietileno glicol com ácido ascórbico pode fornecer eficácia similar e melhor tolerabilidade do que 4 L de polietileno glicol para lavagem intestinal em pacientes idosos entre 60-79 anos.

4 Fev, 2022 | 15:48h

Comparison of 2 L Polyethylene Glycol Plus Ascorbic Acid and 4 L Polyethylene Glycol in Elderly Patients Aged 60–79: A Prospective Randomized Study – Digestive Diseases and Sciences (link para o resumo – $ para o texto completo)

Diretrizes relacionadas:

Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019 – Endoscopy

Bowel preparation before colonoscopy – Gastrointestinal Endoscopy

M-A | Eficácia e segurança de medicamentos biológicos e de moléculas pequenas para pacientes com colite ulcerativa moderada a grave.

4 Fev, 2022 | 15:42h

Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link para o resumo – $ para o texto completo)

Comentário: Review finds upadacitinib most effective for moderate to severe ulcerative colitis remission – ACP Gastroenterology

Revisão | Planejamento de cuidado avançado e objetivos das discussões sobre cuidado no câncer hepático avançado.

4 Fev, 2022 | 15:38h

Advance Care Planning and Goals of Care Discussions in Advanced Liver Disease – Current Hepatology Reports

Revisão | Prevenção da aterosclerose a partir da infância.

4 Fev, 2022 | 15:33h

Prevention of atherosclerosis from childhood – Nature Reviews Cardiology (se o acesso a este link for pago, tente este)

Estudo randomizado | Impacto de máquina portátil normotérmica de perfusão sobre os desfechos de transplante hepático.

4 Fev, 2022 | 15:09h

Impact of Portable Normothermic Blood-Based Machine Perfusion on Outcomes of Liver Transplant: The OCS Liver PROTECT Randomized Clinical Trial – JAMA Surgery

Comentários:

Normothermic Machine Perfusion Improves Outcomes in Liver Transplant Recipients – Physician’s Weekly

Machine Perfusion Cuts Early Graft Dysfunction in Liver Transplantation – MedPage Today (necessário cadastro gratuito)

Conteúdos relacionados:

RCT: Hypothermic machine perfusion in liver transplantation

Transplantation of Discarded Livers Following Viability Testing with Normothermic Machine Perfusion

Comentários no Twitter

Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/PZzvFriJvB pic.twitter.com/2icSfxoLDF

— JAMA Surgery (@JAMASurgery) January 5, 2022

Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/TKEsTf8Htu pic.twitter.com/tg2xDGDyOS

— JAMA Surgery (@JAMASurgery) January 5, 2022

Revisão | Encefalopatia hepática: pensando além da amônia.

4 Fev, 2022 | 14:51h

Hepatic Encephalopathy: Thinking Beyond Ammonia – Clinical Liver Disease

Estudo randomizado | Olanzapina pode melhorar o controle do vômito de fase tardia em crianças recebendo quimioterapia altamente emetogênica.

31 Jan, 2022 | 08:41h

Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial – Journal of Pediatric Hematology/Oncology (link para o resumo – $ para o texto completo)

Resumo de diretriz | Tratamento dos 10 eventos adversos imunológicos mais comuns em pacientes em imunoterapia.

31 Jan, 2022 | 08:39h

Management of the Top 10 Most Common Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy – JCO Oncology Practice

Artigo original: ASCO Guideline Update: Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy.