Fisioterapia Respiratória

Análise Rasch | Desenvolvimento e validação do questionário de impacto dos sintomas para Covid longa (symptom burden questionnaire for long covid – SBQ-LC).

29 Abr, 2022 | 15:15h

Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis – The BMJ

 

Comentário no Twitter

New research developed and validated a symptom burden questionnaire for long covid which has the potential to benefit international clinical trials and inform clinical management https://t.co/akrRleap0W

— The BMJ (@bmj_latest) April 27, 2022

 

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Sintomas persistentes de COVID-19 em estudo comunitário de 606.434 pessoas na Inglaterra.

27 Abr, 2022 | 16:41h

Persistent COVID-19 symptoms in a community study of 606,434 people in England – Nature Communications

 

Comentário no Twitter

Thirty-eight percent of participants from a community-based study of symptoms following COVID-19 reported persistent symptoms that lasted 12 weeks or more, according to an article published in @NatureComms. https://t.co/sAEutdOkSS pic.twitter.com/oCyyXGIRbk

— Nature Portfolio (@NaturePortfolio) April 20, 2022

 

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Covid-19: estudo mostra que somente 1/4 dos pacientes admitidos em hospital sentem-se completamente recuperados após 1 ano.

27 Abr, 2022 | 16:39h

Covid-19: Only a quarter of patients admitted to hospital feel fully recovered after a year, study finds – The BMJ

Estudo original: Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study – The Lancet Respiratory Medicine

Comentário convidado: Long COVID: systemic inflammation and obesity as therapeutic targets – The Lancet Respiratory Medicine

 

Comentário no Twitter (fio – clique para saber mais)

PHOSP-COVID study:
– 232 (29%) of 804 pts fully recovered at 1y
– Female sex, obesity, & IMV = less likely to feel fully recovered
– inflamm mediators📈in those w/ most severe physical, mental health, & cognitive impairments

Read it here: https://t.co/rVZuVDo4xl

— The Lancet Respiratory Medicine (@LancetRespirMed) April 25, 2022

 

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Seguimento de 1 ano de estudo randomizado | Em pacientes em UTI com hipoxemia grave, não houve diferença na mortalidade de longo prazo e na qualidade de vida relacionada à saúde com alvos de oxigenação mais baixos vs. mais altos.

25 Abr, 2022 | 12:42h

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Estudo original: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 

Comentário no Twitter

Lower (8 kPa) vs higher oxygenation (12 kPa) targets: no longterm survival benefit nor HRQoL improvement at 1y in #ICU pts with severe hypoxaemia (HOT-ICU trial cohort). Substantial impairments in several EQ-5D-5L dimensions in survivors in both groups.
🖇️ https://t.co/P48Cd5sIWK pic.twitter.com/JBFEIqDdcB

— Intensive Care Medicine (@yourICM) April 20, 2022

 

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Estudo controlado não randomizado: posição prona em paciente não intubado (média de 4,2 horas/dia) pode não ser benéfica para adultos internados com Covid-19.

21 Abr, 2022 | 12:29h

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Comentários:

Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine

Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP

Putting Hospitalized COVID Patients on Their Belly May Not Be a Good Idea After All – HealthDay

Conteúdos relacionados:

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

 

Comentário no Twitter (fio – clique para saber mais)

Important negative study: non randomized trial finds no clinical benefit to awake proning vs usual care in COVID

No difference in rates of intubation, length of stay, or 28 day mortality

Medicine is humbling. This emphasizes the importance of trials
📄https://t.co/ksh9Ic9XBL
1/ pic.twitter.com/sjHHv4WQs8

— Nick Mark MD (@nickmmark) April 18, 2022

 

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M-A | Prevalência global da condição pós-COVID-19 ou COVID longa.

21 Abr, 2022 | 11:37h

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review – The Journal of Infectious Diseases

Comentário: Global data reveal half may have long COVID 4 months on – CIDRAP

 

Comentário no Twitter (fio – clique para saber mais)

🚨The so far largest meta-analysis of more than 1.5 million infected individuals puts the global prevalence of #LongCovid at 43%. Some additional key findings. 🧵https://t.co/XGu23MV3Ra
1/

— Jonas R. Kunst (@KunstJonas) April 17, 2022

 

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M-A | Metas de oxigênio durante a ventilação mecânica na UTI.

12 Abr, 2022 | 12:20h

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

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Consenso: COVID longa em crianças.

11 Abr, 2022 | 12:57h

Long COVID (post-COVID-19 condition) in children: a modified Delphi process – Archives of Disease in Childhood

Conteúdos relacionados:

First research definition for ‘Long COVID’ in kids and young people formally agreed.

Cohort Study: Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

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Perspectiva | Como estudar a COVID longa grave para compreender os distúrbios pós-infecciosos além da COVID-19.

8 Abr, 2022 | 21:42h

Studying severe long COVID to understand post-infectious disorders beyond COVID-19 – Nature Medicine

Conteúdos relacionados:

Review: Post-acute COVID-19 syndrome.

ESCMID rapid guidelines for assessment and management of long COVID.

ERS statement on Long COVID-19 follow-up.

Proposed subtypes of long-Covid and their respective potential therapies.

EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.

Global surveillance, research, and collaboration needed to improve understanding and management of long COVID.

Provocative study suggests that persistent physical symptoms after COVID-19 infection may be associated more with the belief in having been infected with SARS-CoV-2 than with having laboratory-confirmed COVID-19 infection.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (vários artigos sobre o tema)

2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute sequelae of SARS-CoV-2 infection, and return to play.

Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.

The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.

COVID-19 infections increase risk of heart conditions up to a year later, study finds.

 

Comentário do autor no Twitter (fio – clique para saber mais)

1/ HGE (https://t.co/VMUVMAo1bJ) position paper on #LongCOVID #PACS . By focusing on the most severe patients, w severe organ damage/dysfunction following mild/moderate #COVID19 – we will search for genetic and immunological mechanisms of disease https://t.co/dZQPEoNkhl pic.twitter.com/tgblk7oFQG

— Petter Brodin (@BrodinPetter) April 5, 2022

 

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Revisão e M-A | Reabilitação pulmonar pós-Covid.

8 Abr, 2022 | 17:18h

Estudo 1: The effectiveness of pulmonary rehabilitation for Post-COVID symptoms: A rapid review of the literature – Respiratory Medicine

Estudo 2: Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Analysis – Frontiers in Medicine

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