Farmácia/Notícias da Indústria

Revisão | Reações paradoxais a agentes biológicos nas doenças inflamatórias sistêmicas crônicas.

21 Abr, 2022 | 11:24h

Paradoxical Reactions to Biologicals in Chronic Inflammatory Systemic Diseases – Deutsches Ärzteblatt International

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Revisão | Segurança dos medicamentos antirreumáticos.

21 Abr, 2022 | 11:23h

The Safety of Antirheumatic Drugs – Deutsches Ärzteblatt International

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Terapias endócrinas para cânceres de mama e de próstata: o básico para a atenção primária.

20 Abr, 2022 | 14:46h

Endocrine therapies for breast and prostate cancers: Essentials for primary care – Canadian Family Physician

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M-A | Miopericardite após vacinação contra COVID-19 e vacinação não relacionada a COVID-19.

19 Abr, 2022 | 12:41h

Myopericarditis following COVID-19 vaccination and non-COVID-19 vaccination: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Comentários:

Myopericarditis following COVID-19 vaccination is rare, finds international study – The Lancet

Myopericarditis after COVID-19 vaccination: unexpected but not unprecedented – The Lancet Respiratory Medicine

Study explores myopericarditis incidence and COVID-19 vaccination – News Medical

 

Comentário no Twitter

NEW—Myopericarditis following #COVID19 vaccination is rare, finds international study published in @LancetRespirMed: https://t.co/d3ZRvTWrGB pic.twitter.com/6sHiRyEbTk

— The Lancet (@TheLancet) April 11, 2022

 

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Diretrizes para o monitoramento terapêutico medicamentoso da vancomicina.

19 Abr, 2022 | 12:37h

Clinical Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin in the Framework of Model-Informed Precision Dosing: A Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Pharmaceutics

Diretriz relacionada:

Diretriz: Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Resumo: Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases

 

Comentário no Twitter

🔔Rings Cowbell🔔
New Vancomycin guidelines drop from Japan.

This is the most written about the need for #PrecisionDosing that I have seen.

Give patients the dose they need because #OneSizeFitsNone@SIDPharm @ABsteward @IDstewardship https://t.co/wlwgkqZmXu

— Marc H. Scheetz (@IDPharmacometrx) April 13, 2022

 

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Análise observacional em Israel mostrou que a 4ª dose da vacina da Pfizer pode reduzir o risco de curto prazo dos desfechos adversos relacionados a Covid-19.

18 Abr, 2022 | 15:31h

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

Editorial: Covid-19 Boosters — Where from Here?

Conteúdos relacionados:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines.

Observational study suggests a fourth dose of the Pfizer vaccine provided additional protection against severe disease in patients 60 years of age or older during the Omicron wave in Israel.

Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

Comentário no Twitter

In Israel, a fourth dose of BNT162b2 vaccine effective in reducing the short-term risk of Covid-19–related outcomes among those who had received a third dose at least 4 mos earlier. https://t.co/WtHiR9WbLW pic.twitter.com/yzWRLlgHUi

— NEJM (@NEJM) April 13, 2022

 

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Covid-19: qual é a evidência para o uso do antiviral molnupiravir?

18 Abr, 2022 | 15:30h

Covid-19: What is the evidence for the antiviral molnupiravir? – The BMJ

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Estudo randomizado | Eficácia, segurança e imunogenicidade de uma vacina de enterovírus 71 inativado em bebês e crianças.

18 Abr, 2022 | 15:26h

Efficacy, safety, and immunogenicity of an inactivated, adjuvanted enterovirus 71 vaccine in infants and children: a multiregion, double-blind, randomised, placebo-controlled, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)

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Estudo transversal | Uso de inibidores seletivos de recaptação de serotonina está associado com redução de movimentos medidos.

18 Abr, 2022 | 15:20h

Association of Selective Serotonin Reuptake Inhibitor Use With Abnormal Physical Movement Patterns as Detected Using a Piezoelectric Accelerometer and Deep Learning in a Nationally Representative Sample of Noninstitutionalized Persons in the US – JAMA Network Open

 

Comentário no Twitter

This cross-sectional study found SSRI use was associated with a reduction in measured movements, highlighting the utility of passively collected data for exploring and characterizing adverse drug effects. https://t.co/54ZngDdt8u

— JAMA Network Open (@JAMANetworkOpen) April 7, 2022

 

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Estudo randomizado | Comparação entre naloxona intranasal e intramuscular nas overdoses por opioides tratadas pela equipe de ambulância.

18 Abr, 2022 | 15:16h

Comparison of intranasal and intramuscular naloxone in opioid overdoses managed by ambulance staff: a double-dummy, randomised, controlled trial – Addiction

Comentário: Breathing restored within 10 minutes for 80% of overdose patients using nasal spray – Norwegian University of Science and Technology

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