Farmácia/Notícias da Indústria

Vacinação contra SARS-CoV-2 e miocardite em um estudo de coorte nórdico com 23 milhões de residentes.

25 Abr, 2022 | 12:26h

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Editorial: Communicating the Benefits of Vaccination in Light of Potential Risks

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Diretriz preliminar USPSTF | Mulheres na pós-menopausa não deveriam usar hormonioterapia para evitar problemas crônicos de saúde.

21 Abr, 2022 | 12:44h

Diretriz preliminar de recomendação: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons – U.S. Preventive Services Task Force

Comunicado de imprensa: Task Force Issues Draft Recommendation Statement on Hormone Therapy for Preventing Chronic Conditions in Postmenopausal People – U.S. Preventive Services Task Force

Comentário: USPSTF Advises Against Hormone Therapy to Prevent Chronic Conditions – HealthDay

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Estudo observacional sugere que a coprescrição de inibidores da fosfodiesterase tipo 5 (p. e., sildenafila) e nitratos orais não está associada a risco aumentado de desfechos cardiovasculares adversos em homens com doença cardíaca isquêmica.

21 Abr, 2022 | 12:39h

Adverse Events Associated With Coprescription of Phosphodiesterase Type 5 Inhibitors and Oral Organic Nitrates in Male Patients With Ischemic Heart Disease: A Case-Crossover Study – Annals of Internal Medicine

Comentários:

PDE5 inhibitors didn’t increase cardiovascular events in men on nitrates for heart disease – ACP Internist

PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD – HealthDay

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Estudos destacam o potencial da vacina contra meningite para prevenir a gonorreia.

21 Abr, 2022 | 12:35h

Comentário: Studies highlight meningitis vaccine’s potential against gonorrhea – CIDRAP

Comunicado de imprensa: Threat of untreatable gonorrhoea could be tackled using an existing meningitis vaccine – The Lancet

Estudo 1: Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational study – The Lancet Infectious Diseases (link para o resumo – $ para o texto completo)

Estudo 2: Effectiveness and impact of the 4CMenB vaccine against invasive serogroup B meningococcal disease and gonorrhoea in an infant, child, and adolescent programme: an observational cohort and case-control study – The Lancet Infectious Diseases (link para o resumo – $ para o texto completo)

Estudo 3: Public health impact and cost-effectiveness of gonorrhoea vaccination: an integrated transmission-dynamic health-economic modelling analysis – The Lancet Infectious Diseases

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M-A | Associação entre imunoterápicos para o tratamento do câncer e eventos adversos neurológicos.

21 Abr, 2022 | 12:15h

Association of Immune Checkpoint Inhibitors With Neurologic Adverse Events: A Systematic Review and Meta-analysis – JAMA Network Open

Comentário convidado: Neurological Toxic Effects Associated With Treatment With Immune Checkpoint Inhibitors—Are We Really Safer Now? – JAMA Network Open

Conteúdos relacionados:

Autoimmune Encephalitis Related to Cancer Treatment With Immune Checkpoint Inhibitors: Systematic Review – Neurology (link para o resumo – $ para o texto completo)

Neurological complications of immune checkpoint inhibitors: what happens when you ‘take the brakes off’ the immune system – Therapeutic Advances in Neurologic Disorders

 

Comentário no Twitter

Meta-analysis of 39 RCTs found immune checkpoint inhibitors have lower risk of neurological adverse effects compared to cytotoxic chemotherapy, but higher than placebo, across a range of malignancies. https://t.co/02GhICcu5H

— JAMA Network Open (@JAMANetworkOpen) April 19, 2022

 

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Liberadas para estudo clínico as vacinas candidatas da Sinopharm e Sinovac específicas para variante Ômicron da COVID.

21 Abr, 2022 | 11:42h

Omicron-specific Sinopharm, Sinovac COVID vaccine candidates cleared for clinical trial – Reuters

 

Comentário no Twitter

In China, #Omicron-specific vaccines are slated for clinical trials. The vaccine candidates were developed by a Sinopharm subsidiary and Sinovac Biotech. The vaccines are headed to clinical trials in Hong Kong https://t.co/6Y9LsGCKbn

— delthia ricks 🔬 (@DelthiaRicks) April 17, 2022

 

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Revisão sistemática da eficácia e da efetividade da vacina para COVID-19 contra infecção e doença pelo SARS-CoV-2.

21 Abr, 2022 | 11:35h

A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease – Open Forum Infectious Diseases

 

Comentário no Twitter

🆕💥💥Systematic Review collected efficacy & effectiveness values by vaccine platform, disease outcome, number of doses, & SARS-CoV-2 variants
The spread of the Omicron beginning late 2021 is at least partially driven by reductions in vaccine effectiveness https://t.co/A7hDTQGY4K

— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) April 18, 2022

 

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Estudo randomizado | Alopurinol é não inferior ao febuxostate no controle de crises de gota.

21 Abr, 2022 | 11:32h

Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management – NEJM Evidence (link para o resumo – $ para o texto completo)

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Análise de uma intervenção em serviços de emergência médica visando a reduzir os erros de dosagem de epinefrina em bebês.

21 Abr, 2022 | 11:28h

Analysis of an Intervention for Emergency Medical Services Personnel to Reduce Epinephrine Dosing Errors in Infants – JAMA Network Open

 

Comentário no Twitter

In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

 

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Estudo de coorte | Associação do tratamento com antipsicóticos, antidepressivos ou ambos com transtornos do movimento e convulsões entre crianças e adolescentes com depressão.

21 Abr, 2022 | 11:26h

Association of Treatment With Antipsychotics, Antidepressants, or Both With Movement Disorders and Seizures Among Children and Adolescents With Depression in Korea – JAMA Network Open

 

Comentário no Twitter

In this cohort study, adjunctive antipsychotics with antidepressants were associated with movement disorders and seizures compared with antidepressant monotherapy in children and adolescents with depression. https://t.co/3SVKEThwkR

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

 

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