Acesso livre
Acesso livre

Farmácia/Notícias da Indústria

Estudo randomizado | Fentermina/topiramato para tratamento de obesidade na adolescência.

3 Mai, 2022 | 16:45h

Phentermine/Topiramate for the Treatment of Adolescent Obesity – NEJM Evidence

 

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Estudo randomizado | Curso antibiótico com duração estendida vs. padrão em crianças menores de 5 anos de idade com pneumonia adquirida na comunidade em ambientes de alto risco.

2 Mai, 2022 | 14:06h

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Conteúdos relacionados:

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 

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Revisão | Compreendendo a segurança da vacina e as funções do FDA e do CDC.

2 Mai, 2022 | 14:04h

Understanding Vaccine Safety and the Roles of the FDA and the CDC – New England Journal of Medicine

 

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OMS revela a chocante extensão da propaganda de fórmulas lácteas.

2 Mai, 2022 | 14:00h

Comunicado de imprensa: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization

Relatório: Scope and impact of digital marketing strategies for promoting breastmilk substitutes – World Health Organization

Conteúdo relacionado: More than half of parents and pregnant women exposed to aggressive formula milk marketing – WHO, UNICEF – World Health Organization

 

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Covid-19: qual é a evidência para o uso do antiviral Paxlovid?

29 Abr, 2022 | 15:16h

Covid-19: What is the evidence for the antiviral Paxlovid? – The BMJ

Conteúdos relacionados:

Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization

A living WHO guideline on drugs for covid-19 – The BMJ

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

Especialistas temem que os EUA padronizem o reforço anual de vacinas contra Covid sem dados suficientes.

29 Abr, 2022 | 15:11h

Experts fear U.S. may default to annual Covid boosters without sufficient data – STAT

 

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Revisão das evidências e guia prático de uso clínico | Inibidores do cotransportador sódio-glicose 2 na insuficiência cardíaca aguda.

29 Abr, 2022 | 14:58h

Sodium-glucose Co-transporter 2 Inhibitors in Acute Heart Failure: A Review of the Available Evidence and Practical Guidance on Clinical Use – Reviews in Cardiovascular Medicine

 

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Estudo de fase 2b | Imunização contra o vírus sincicial respiratório durante a gestação.

29 Abr, 2022 | 14:53h

Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentário: RSV Prefusion F Protein-Based Immunization Studied in Pregnancy – HealthDay

 

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Revisão sistemática | Artrite associada a imunoterápicos para o tratamento do câncer.

29 Abr, 2022 | 14:42h

Checkpoint Inhibitor–Associated Arthritis: A Systematic Review of Case Reports and Case Series – Journal of Clinical Rheumatology

Conteúdo relacionado: Half of People with RA Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment – American College of Rheumatology

Estudo observacional sugere que a suplementação de cálcio pode aumentar os desfechos adversos em pacientes com estenose aórtica.

28 Abr, 2022 | 12:14h

Supplemental calcium and vitamin D and long-term mortality in aortic stenosis – Heart

Comunicado de imprensa: Calcium supps linked to earlier death in older people with heart valve disease – BMJ

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