Farmácia/Notícias da Indústria

M-A | Inibidores orais da Janus-quinase no tratamento da dermatite atópica.

13 Jun, 2022 | 13:42h

Oral Janus kinase inhibitors in the treatment of atopic dermatitis: A systematic review and meta-analysis – Skin Health and Disease

Comentário: Systematic Review Suggests Oral JAK Inhibitors Effective in AD – HCP Live

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M-A | Antidepressivos em crianças e adolescentes com transtorno depressivo maior e a influência da resposta ao placebo.

6 Jun, 2022 | 11:10h

Antidepressants in children and adolescents with major depressive disorder and the influence of placebo response: A meta-analysis – Journal of Affective Disorders (link para o resumo – $ para o texto completo)

Comentários:

Antidepressants Have Small Effect Sizes for the Treatment of Major Depressive Disorder Among Children – Psychiatry Advisor

Antidepressant Effect Sizes Modest for Pediatric Major Depressive Disorder – Consultant360

 

Comentário no Twitter

MA: The SMD among all studies of antidepressants in C&A with MDD was 0.12 (0.08-0.17), a very small ES, lower than that seen in studies of adults with MDD. When the MA was limited to studies with a low mean placebo response, the SMD increased to 0.19 https://t.co/hPYvta4rgf

— PfOL (@psychopharmacol) March 23, 2022

 

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Diretriz da BSR para tratamento de artrite psoriática com medicamentos biológicos e antirreumáticos modificadores de doença (disease modifying antirheumatic drugs – DMARD).

2 Jun, 2022 | 14:10h

The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs – Rheumatology

Resumo executivo: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs – Rheumatology

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Metanálise em rede | Efetividade dos regimes heterólogos e homólogos de vacinação contra Covid-19.

2 Jun, 2022 | 14:05h

Effectiveness of heterologous and homologous covid-19 vaccine regimens: living systematic review with network meta-analysis – The BMJ

Comunicado de imprensa: Three doses of the same or mixed covid jabs work equally well against infections – BMJ

Comentário: Three jabs best for preventing Covid infections, global analysis finds – The Guardian

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Estudo de coorte | Associação entre exposição pré-natal a medicamentos anticonvulsivos e risco de autismo e incapacidade intelectual.

2 Jun, 2022 | 13:58h

Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability – JAMA Neurology

Entrevista com a autora: Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability – JAMA

Comentários:

Prenatal Exposure to Certain Antiseizure Meds Linked to Autism – HealthDay

Pregnant women who take common epilepsy drugs up to four times as likely to have child with autism or learning disabilities, study warns – Daily Mail

Conteúdos relacionados:

Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs – Neurology (link para o resumo – $ para o texto completo)

Thirteen UK healthcare bodies launch ‘pragmatic’ guidance on valproate use – Royal College of General Practitioners

Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Risk for Attention-Deficit/Hyperactivity Disorder in Offspring – JAMA Network Open

Educational attainment of children born to mothers with epilepsy – Journal of Neurology, Neurosurgery, and Psychiatry (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Nordic study of 4.5 million children found an association between prenatal exposure to topiramate and valproate and child intellectual disability and #autism. https://t.co/UH2THznPiV

— JAMA Neurology (@JAMANeuro) May 31, 2022

 

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Estudos randomizados | Tratamento com favipiravir para influenza não complicada em adultos.

2 Jun, 2022 | 13:49h

Favipiravir Treatment of Uncomplicated Influenza in Adults: Results of Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Trials – Journal of Infectious Diseases

Comentário: Mixed Bag for Antiviral Favipiravir in Flu — Two phase III trials show conflicting results on clinical improvement – MedPage Today (necessário cadastro gratuito)

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Breve revisão | Administração de vasopressores por meio de cateteres venosos periféricos.

2 Jun, 2022 | 13:35h

Administration of vasopressors through peripheral venous catheters – Canadian Medical Association Journal

Conteúdos relacionados:

Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis – Critical Care

Complication of vasopressor infusion through peripheral venous catheter: A systematic review and meta-analysis – The American Journal of Emergency Medicine (link para o resumo – $ para o texto completo)

An update on peripheral vasopressors – First10EM

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Consenso | Potencial nefrotóxico de 167 medicamentos em adultos criticamente doentes.

31 Mai, 2022 | 12:36h

Consensus Obtained for the Nephrotoxic Potential of 167 Drugs in Adult Critically Ill Patients Using a Modified Delphi Method – Drug Safety (se o acesso a este link for pago, tente este)

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Análise/Opinião | As consequências não intencionais da política de vacinas contra COVID-19: “pode ser que mandatos, passaportes e restrições causem mais prejuízos que benefícios.”

31 Mai, 2022 | 12:33h

The unintended consequences of COVID-19 vaccine policy: why mandates, passports and restrictions may cause more harm than good – BMJ Global Health

 

Comentário no Twitter (fio – clique para saber mais)

📢 Our paper on COVID-19 vaccine policy has been published💉🦠

We discuss 12 unintended consequences of mandates and passports across society

& argue that pandemic vaccine policies have caused more social harm than good

Read the paper: https://t.co/TeyTki0nWI pic.twitter.com/BRJQRURbUc

— Kevin Bardosh (@KevinBardosh) May 26, 2022

 

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Opinião | Efeitos adversos de aquisições na indústria farmacêutica.

31 Mai, 2022 | 11:58h

Adverse effects of acquisitions in the pharmaceutical industry – Nature Medicine

 

Comentário no Twitter

Publicly funded research leads to the development of many new drugs, but the profits are largely reaped by big pharmaceutical companies, which can reduce competition and patients’ access to medicines, a @NatureMedicine Comment article argues. https://t.co/kUtjZa1ps1 pic.twitter.com/ccBJvpCP1t

— Nature Portfolio (@NaturePortfolio) May 26, 2022

 

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