Acesso livre
Acesso livre

Farmácia/Notícias da Indústria

Estudo randomizado fase 2 | Segurança e imunogenicidade da vacina da AstraZeneca em crianças de 6-17 anos de idade.

19 Jun, 2022 | 15:37h

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6–17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial – The Lancet

Comentário convidado: Increasing children’s global access to COVID-19 vaccines – The Lancet


Revisão sistemática | Inibidores da Janus quinase para o tratamento de COVID-19.

19 Jun, 2022 | 14:38h

Janus kinase inhibitors for the treatment of COVID‐19 – Cochrane Library

Resumo: Are systemic Janus kinase inhibitors an effective treatment for people with COVID-19? – Cochrane Library


Segurança comparativa das vacinas BNT162b2 e mRNA-1273 em uma coorte nacional de veteranos nos EUA.

19 Jun, 2022 | 14:27h

Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans – JAMA Internal Medicine

Comentário: Few differences in safety profiles of Moderna, Pfizer COVID-19 vaccines – Harvard T.H. Chan School of Public Health

 

Comentário no Twitter

 


Recomendação de consenso | Guia para realizar revisões de medicamentos em idosos com câncer.

19 Jun, 2022 | 14:12h

How-to guide for medication reviews in older adults with cancer: A Young International Society of Geriatric Oncology and Nursing & Allied Health Interest Group initiative – Journal of Geriatric Oncology

Conteúdo relacionado: Deprescribing in Palliative Cancer Care – Life


Estudo de coorte | Risco de longo prazo de overdose ou crise de saúde mental após redução de dose e opioides.

19 Jun, 2022 | 14:08h

Long-term Risk of Overdose or Mental Health Crisis After Opioid Dose Tapering – JAMA Network Open

Editorial: New Data on Opioid Dose Reduction—Implications for Patient Safety – JAMA Network Open

Comunicado de imprensa: Increased overdose and mental health risks persist two years after opioid dose reduction –  UC Davis Center for Healthcare Policy and Research


Diretriz BSH para manejo hematológico de hemorragia de grande volume.

19 Jun, 2022 | 13:44h

A guideline for the haematological management of major haemorrhage: a British Society for Haematology Guideline – British Journal of Haematology


Estudo randomizado | Tixagevimabe-cilgavimabe intramuscular pode ser benéfico para adultos não vacinados e não internados com Covid-19.

19 Jun, 2022 | 13:33h

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine

Comentários:

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID – News Medical

Expert reaction to results of the TACKLE Phase 3 trial of Evusheld (tixagevimab and cilgavimab) for treating early COVID-19 in outpatients – Science Media Centre

 

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Inibidor de SGLT2 reduz o risco de hiperpotassemia em pacientes com insuficiência cardíaca.

19 Jun, 2022 | 13:15h

Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled – European Heart Journal

Editorial: Emerging role for SGLT2 inhibitors in mitigating the risk of hyperkalaemia in heart failure

Conteúdo relacionado: Effects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial – European Heart Journal

 

Comentário no Twitter

Sob a licença de https://creativecommons.org/licenses/by-nc/4.0/


Estudo de coorte | Desfechos de longo prazo com o uso precoce de antipsicóticos injetáveis de ação prolongada na esquizofrenia.

19 Jun, 2022 | 13:10h

Long-term Outcomes of Early Use of Long-Acting Injectable Antipsychotics in Schizophrenia – The Journal of Clinical Psychiatry (link to abstract – $ for full-text)

Comentário: Patients With Schizophrenia Switched Early to LAIs Show Markedly Better Long-Term Outcomes – Psychiatric News Alert

Conteúdos relacionados:

Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis – The Lancet (link para o resumo – $ para o texto completo)

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link para o resumo – $ para o texto completo)

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link para o resumo – $ para o texto completo)

Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early-Phase Schizophrenia: A Randomized Clinical Trial – JAMA Psychiatry


Revisão sistemática | Oxicodona para dor relacionada a câncer.

19 Jun, 2022 | 13:05h

Oxycodone for cancer‐related pain – Cochrane Library

Resumo: Oxycodone for cancer-related pain in adults – Cochrane Library


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