Farmácia/Notícias da Indústria

Diretriz 2022 da ACR para manejo perioperatório da medicação antirreumática em pacientes com doenças reumáticas submetidos a artroplastia eletiva total de quadril ou de joelho.

12 Jul, 2022 | 11:44h

2022 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty – Arthritis Care & Research (PDF)

Ver também: Guideline Summary (PDF)

 

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Revisão sistemática | Métodos médicos para o aborto no 1º trimestre.

12 Jul, 2022 | 11:37h

Medical methods for first trimester abortion – Cochrane Library

Resumo: Are medical methods for early termination of pregnancy effective and do they cause unwanted effects? – Cochrane Library

 

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Estudo randomizado | Albumina 20% vs. plasmalyte em pacientes com cirrose e hipotensão induzida pela sepse.

12 Jul, 2022 | 11:36h

A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial] – Journal of Hepatology

 

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M-A | Não há evidências convincentes que apoiem o uso de progesterona vaginal em gestações únicas com histórico de parto prematuro espontâneo.

12 Jul, 2022 | 11:23h

Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? Evidence from a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link para o resumo – $ para o texto completo)

Comunicado de imprensa: Progress toward personalized prevention of preterm birth: When progesterone works and when it does not – Wayne State University School of Medicine

Conteúdos relacionados:

A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy – New England Journal of Medicine

Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial – American Journal of Obstetrics & Gynecology (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

AJOG Systematic Review: Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? – Effect of vaginal progesterone on preterm birth <37 weeks of gestation https://t.co/fsPlSZCnsr pic.twitter.com/2z6g3CFgX4

— AJOG (@AJOG_thegray) April 25, 2022

 

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Análise provisória | Sabizabulina oral para adultos de alto risco internados com Covid-19.

11 Jul, 2022 | 13:59h

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence

 

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Estudo randomizado | Plasma convalescente neutralizante de COVID-19 não traz benefícios a adultos internados com a doença.

11 Jul, 2022 | 13:58h

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized with COVID-19: A Blinded Randomized Placebo-Controlled Trial – CHEST

Comentário: Study shows convalescent plasma doesn’t benefit severely ill patients hospitalized with COVID-19 – Vanderbilt University Medical Center

 

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M-A | Associações entre uso de diuréticos tiazídicos e câncer de pele.

11 Jul, 2022 | 13:55h

Associations of thiazide use with skin cancers: a systematic review and meta-analysis – BMC Medicine

Conteúdos relacionados:

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine

Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark – Journal of the American Academy of Dermatology

 

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M-A | Terapia medicamentosa antitireoidiana na gestação e risco de anomalias congênitas.

11 Jul, 2022 | 13:42h

Antithyroid drug therapy in pregnancy and risk of congenital anomalies: Systematic review and meta-analysis – Clinical Endocrinology

 

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M-A | Exposição pré-natal a antibiótico, asma e atopia.

11 Jul, 2022 | 13:38h

Prenatal antibiotic exposure, asthma, and the atopic march: A systematic review and meta-analysis – Allergy

 

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Estudo randomizado | Efeitos relacionados a dose de quetamina para sintomas resistentes a antidepressivos do transtorno do estresse pós-traumático em militares veteranos e ativos.

11 Jul, 2022 | 13:36h

Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial – Neuropsychopharmacology (se o acesso a este link for pago, tente este)

 

Comentário no Twitter

Glad to see this work published. Contrary to predictions from small studies, #ketamine failed in the largest #PTSD clinical trial.

Future studies should test the lower dose and 3x/wk. @npp_journal @YalePsych @bcmhouston @netteaverillhttps://t.co/7NcFsNTMKw

— Chadi Abdallah (@ChadiAbdallah3) January 19, 2022

 

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