Acesso livre
Acesso livre

Farmácia/Notícias da Indústria

Estudo randomizado | Tratamento de rotina com fluoxetina não reduz a incidência de depressão após AVC.

4 Ago, 2021 | 12:14h

Depression Outcomes Among Patients Treated With Fluoxetine for Stroke Recovery: The AFFINITY Randomized Clinical Trial – JAMA Neurology (free for a limited period)

Editorial: Poststroke Selective Serotonin Reuptake Inhibitors—Do They Work for Anything? (gratuito por tempo limitado)

Conteúdos relacionados:

[Abstract Only] Randomized trial: Fluoxetine does not improve functional recovery after acute stroke

Randomized Trial: Effects of Fluoxetine on Functional Outcomes After Acute Stroke

Estudo randomizado | Midodrina pode reduzir a recorrência de síncope vasovagal.

4 Ago, 2021 | 12:12h

Midodrine for the Prevention of Vasovagal Syncope: A Randomized Clinical Trial – Annals of Internal Medicine

Comentário: Midodrine Cuts Recurrent Syncope in Young, Healthy Patients – HealthDay

Resumo para pacientes: Summary for Patients: Midodrine to Prevent Fainting – Annals of Internal Medicine

 

Comentário no Twitter

 

Estudo randomizado | Pimavanserina na psicose relacionada à demência.

3 Ago, 2021 | 11:10h

Trial of Pimavanserin in Dementia-Related Psychosis – New England Journal of Medicine

Como descartar medicações com segurança.

3 Ago, 2021 | 11:06h

How to safely dispose of medication – Medical News Today

Recomendações da ACOG e da SMFM para a vacinação contra COVID-19 em gestantes – “ACOG encoraja seus membros a recomendar enfaticamente a vacinação para suas pacientes.”

2 Ago, 2021 | 19:18h

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM)

Leituras adicionais:

Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care

COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians

Comentários:

Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press

Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes

 

Comentário no Twitter

 

Opinião | Gestantes devem se vacinar contra COVID? As evidências mostram que é seguro e eficaz.

2 Ago, 2021 | 19:16h

Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective – The Conversation

O que todo intensivista deveria saber sobre o tocilizumabe.

2 Ago, 2021 | 19:11h

What every intensivist should know about Tocilizumab – Critical Care

Conteúdos relacionados:

Tocilizumab in COVID-19 therapy: who benefits, and how?

A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.

M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.

M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

Reforços das vacinas contra COVID nos países ricos geram indignação.

2 Ago, 2021 | 19:06h

COVID boosters for wealthy nations spark outrage – Nature

Conteúdo relacionado: MSF: No COVID-19 booster shots anywhere before healthcare workers and vulnerable people everywhere have access – Médecins Sans Frontières/Doctors Without Borders

Cientistas discutem a questão do reforço da vacina contra COVID-19.

2 Ago, 2021 | 19:04h

Scientists Grapple With Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead – Health Policy Watch

Investigação | FDA permite que o uso de medicamentos sem benefício clínico comprovado permaneça por anos após aprovação preliminar.

2 Ago, 2021 | 18:52h

FDA allows drugs without proven clinical benefit to languish for years on accelerated pathway – The BMJ

Comunicado de imprensa: Investigation finds nearly half of drugs granted FDA ‘fast track’ approval lack proven clinical benefit – The BMJ

Comentário: Over 100 Drugs Given Speedy Approvals Still Lack Proof of Clinical Efficacy – MedPage Today (necessário cadastro gratuito)

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