Estudos Randomizados
Estudo randomizado | Triagem da embolia pulmonar aguda para o tratamento domiciliar pelos critérios Hestia vs. PESI simplificado – As ferramentas tiveram eficácia similar e mais de um terço dos pacientes foram tratados em casa, com baixa incidência de complicações.
11 Ago, 2021 | 10:34h
Comentário no Twitter
Triaging acute pulmonary embolism for home treatment by Hestia or simplified PESI criteria: the HOME-PE randomized trial #EHJ #PE #PERThttps://t.co/gszusChSyU pic.twitter.com/NOyKYsVQHo
— EHJ Editor-in-Chief (@ehj_ed) August 10, 2021
Um vasto estudo sobre tratamento contra COVID-19, organizado pela OMS, está recomeçando. Estes são os medicamentos em análise.
10 Ago, 2021 | 12:39hA giant trial of COVID-19 treatments is restarting. Here are the drugs it’s betting on – Science
Conteúdo relacionado: WHO Solidarity trial to restart with focus on drugs that act on immune responses caused by Covid-19.
Dar e receber: atribuição de tratamento ético em estudos controlados.
10 Ago, 2021 | 12:30hGiving and taking: ethical treatment assignment in controlled trials. – The James Lindt Library
Comentário no Twitter
It was a pleasure and an honour to collaborate with @iainchalmersTTi in writing this piece https://t.co/TP66e4FAOd on ethical issue in treatment assignment in clinical trials. #clinicaltrials
— Stephen John Senn (@stephensenn) August 9, 2021
Análise secundária de estudo randomizado mostra que a dapagliflozina é segura para pacientes no estágio 4 da doença renal crônica.
10 Ago, 2021 | 12:28hComentários:
No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay
[Preprint] Estudo randomizado | Estratégias respiratórias não invasivas na insuficiência respiratória aguda em pacientes com COVID-19 – CPAP reduziu o desfecho composto de entubação ou morte em 30 dias; o uso do cateter nasal de alto fluxo não foi associado a desfechos melhores.
6 Ago, 2021 | 11:58hComentário: Covid: Pressured oxygen reduces ventilator need – BBC
Comentário no Twitter (fio – clique para saber mais)
RECOVERY-RS results out, and confirm what most of us have been doing:
CPAP reduces intubation/mortality by 28% compared with no CPAP/HFNO (composite outcome, mostly intubation)
Nasal high flow not so successful1/https://t.co/bcB2sTdAsu pic.twitter.com/fvT8IbyxUr
— 𝚃𝚘𝚖 𝙻𝚊𝚠𝚝𝚘𝚗 💙 (@LawtonTri) August 5, 2021
Estudo randomizado | Combinação de anticorpos REGEN-COV subcutâneos evitou infecção sintomática por Covid-19 em contactantes de pessoas infectadas.
5 Ago, 2021 | 11:57hSubcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 – New England Journal of Medicine
Conteúdos relacionados:
Comentário no Twitter
Subcutaneous REGEN-COV prevented symptomatic #COVID19 and asymptomatic #SARSCoV2 infection in previously uninfected household contacts. https://t.co/rRNFTjS9hX pic.twitter.com/B7qXeyWKUb
— NEJM (@NEJM) August 4, 2021
Estudo randomizado | Antibioticoterapia por 7 dias é tão boa quanto por 14 dias para homens com infecção de trato urinário que estejam sem febre.
2 Ago, 2021 | 16:51hEffect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)
Editorial: Shorter Courses of Antibiotics for Urinary Tract Infection in Men (gratuito por tempo limitado)
Comentário: Study Supports Shorter Antibiotic Course for Afebrile Men With UTI – MPR
Comentário no Twitter
Practice changing study, we always consider UTI in men as a complicated disease and we usually treat for longer time sometimes even more than 14 days, this study found that you can treat for shorter time ~7 days #IDTwitter #medtwitter #TwitteRx https://t.co/LSWYTAG15y
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) July 27, 2021
Estudo randomizado por clusters | Eficácia de uma intervenção personalizada para reduzir o uso de antibióticos no tratamento de infecções do trato urinário em residentes de casas de repouso.
27 Jul, 2021 | 10:14hEffectiveness of a tailored intervention to reduce antibiotics for urinary tract infections in nursing home residents: a cluster, randomised controlled trial – The Lancet Infectious Diseases (link para o resumo – $ para o texto completo)
Comentário no Twitter
In this open-label, cluster randomised controlled trial, there was reduction in the number of antibiotic prescriptions for urinary tract infections by 58% in Danish nursing home residents without substantially increasing the risk of all-cause hospitalisa… https://t.co/LXO0LIFmTU
— Abid Hussain (@MicrobLog_me_uk) July 23, 2021
Estudo randomizado | Monitoramento remoto e em tempo real durante a quimioterapia para câncer pode reduzir o impacto dos sintomas e melhorar a qualidade de vida.
26 Jul, 2021 | 10:00hComentários:
Remote 24-hour monitoring shows sizable, positive effect on cancer patients – BMJ
Remote Monitoring System Reduces Chemotherapy Symptom Burden – HealthDay
eSMART trial adds support for remote symptom monitoring in people with cancer – medwire News
Relacionado:
Study: Cancer patients benefit from using automated device to manage their symptoms
Study: Web-Based Symptom Monitoring Increases Overall Survival in Lung Cancer
Comentário no Twitter
👇🏼 Results from an RCT, conducted at multiple centres across Europe, showing the benefits of remote patient monitoring and highlighting the vital role it will play in services going forward – congratulations @roma_maguire @Lisa_McCann_ and colleagues https://t.co/8zWrykJEjS
— Katie McMillan (@KathrynMc91) July 22, 2021
Estudo randomizado | Dolutegravir ou darunavir em combinação com zidovudina ou tenofovir no tratamento do HIV.
23 Jul, 2021 | 10:02hDolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentário: Dolutegravir Confirmed as Effective Second-Line HIV Therapy; Recycling Tenofovir Noninferior to Zidovudine – Medscape (necessário cadastro gratuito)