Estudos Randomizados

Estudo randomizado | Fototerapia domiciliar em neonatos a termo melhora o vínculo parental e o estresse.

10 Fev, 2022 | 13:22h

Home phototherapy of term neonates improves parental bonding and stress: Findings from a randomised controlled trial – Acta Paediatrica

 

Comentário no Twitter

Does treating Jaundice in babies at home, as compared to at hospital, improves parental bonding and reduces parental stress?

A new RCT published @ActaPaediatrica by Swedish researchers #EBNEOAlerts #neoEBM #FOAMNeohttps://t.co/InjkdrC5JY pic.twitter.com/BaGs86Hf8t

— Evidence-Based Neo (@EBNEO) January 3, 2022

 

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Estudo randomizado sugere que é seguro conter a antibioticoprofilaxia em pacientes submetidos a ressecção prostática transuretral sem piúria pré-operatória ou cateter de longa permanência pré-operatório.

10 Fev, 2022 | 13:01h

Antimicrobial Prophylaxis in Transurethral Resection of the Prostate: Results of a Randomized Trial – The Journal of Urology (link para o resumo – $ para o texto completo)

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Estudo randomizado | Cetamina é um tratamento eficaz no curto prazo para alguns pacientes com risco de suicídio no hospital.

4 Fev, 2022 | 17:37h

Comunicado de imprensa: Ketamine is a short-term effective treatment for some suicidal patients in hospital – BMJ

Artigo original: Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial – The BMJ

Editorial: Ketamine for suicidal ideation – The BMJ

Conteúdos relacionados:

RCT: Ketamine induced remission in 46% of patients but was NOT non-inferior to electroconvulsive therapy for the treatment of hospitalized patients with unipolar depression.

Systematic Review: Ketamine for the treatment of mental health and substance use disorders.

Phase 2 RCT: Adjunctive ketamine with relapse prevention–based psychological therapy shows promise for the treatment of alcohol use disorder.

RCT: Effects of ketamine vs. midazolam on neurocognition at 24 hours in depressed patients with suicidal ideation.

Randomized trial: Repeated Ketamine administration for chronic posttraumatic stress disorder

Ketamine and Depression: A Narrative Review

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Desfechos de sobrevida de 5 anos do PACIFIC Trial: durvalumabe pós-quimioradioterapia no câncer de pulmão não pequenas células estágio III.

4 Fev, 2022 | 17:15h

Five-Year Survival Outcomes From the PACIFIC Trial: Durvalumab After Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer – Journal of Clinical Oncology

Estudo original: Randomized Trial: Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC

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Estudo randomizado| Uso profilático de luvas compressoras reduz a incidência de edema de braço em mulheres sob alto risco de linfedema relacionado a câncer de mama.

4 Fev, 2022 | 17:14h

Prophylactic Use of Compression Sleeves Reduces the Incidence of Arm Swelling in Women at High Risk of Breast Cancer–Related Lymphedema: A Randomized Controlled Trial – Journal of Clinical Oncology

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Estudo randomizado e controlado por cluster | Uma rede inovadora de telemedicina para melhorar o tratamento de doenças infecciosas em pacientes críticos e ambulatoriais.

4 Fev, 2022 | 16:45h

An innovative telemedical network to improve infectious disease management in critically ill patients and outpatients: a stepped-wedge, cluster randomized controlled trial (TELnet@NRW) – Journal of Medical Internet Research

Conteúdos relacionados:

The “Choosing Wisely” initiative in infectious diseases – German Society of Infectious Diseases (link para o resumo – $ para o texto completo)

Infectious Diseases Society of America: Five Things Physicians and Patients Should Question

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Estudo randomizado | Em pacientes com síndrome da dor regional complexa, o bloqueio ganglionar simpático lombar com toxina botulínica tipo A pode reduzir a intensidade da dor.

4 Fev, 2022 | 16:23h

Botulinum Toxin Type A for Lumbar Sympathetic Ganglion Block in Complex Regional Pain Syndrome: A Randomized Trial – Anesthesiology

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Estudo randomizado por cluster | Em pacientes idosos submetidos a procedimentos cirúrgicos eletivos, um programa de prevenção não farmacológica multimodal reduziu a ocorrência de delirium pós-cirúrgico e os dias com delirium.

4 Fev, 2022 | 15:56h

Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial – JAMA Surgery

Entrevista com as autoras: Effective Delirium Prevention in Older Persons After Elective Surgery

 

Comentário no Twitter

Study suggests implementing a multifaceted multidisciplinary prevention intervention will improve care and outcomes in older patients undergoing elective general and orthopedic procedures https://t.co/lHU59ca5m5 pic.twitter.com/oj76KiV4It

— JAMA Surgery (@JAMASurgery) December 15, 2021

 

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Estudo randomizado | Segurança e eficácia da agomelatina em crianças e adolescentes com transtorno depressivo maior que estão recebendo aconselhamento psicológico.

4 Fev, 2022 | 15:52h

Safety and efficacy of agomelatine in children and adolescents with major depressive disorder receiving psychosocial counselling: a double-blind, randomised, controlled, phase 3 trial in nine countries – The Lancet Psychiatry (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

RCT: 10 to 25 mg/day agomelatine resulted in an improvement versus placebo in CDRS-R raw score of 4·22 (0·63–7·82) at 12 weeks in C&A with MDD, with a similar effect for fluoxetine. The overall effect was confirmed in adolescents, but not in children https://t.co/keecz57fQw

— PfOL (@psychopharmacol) December 23, 2021

 

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Estudo randomizado | Eficácia e segurança do risankizumabe para artrite psoriática ativa.

4 Fev, 2022 | 15:43h

Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 1 trial – Annals of Rheumatic Diseases

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