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Emergências e UTI Pediátrica

Diretrizes 2022 do SCCM sobre prevenção e tratamento de dor, agitação, bloqueio neuromuscular e delirium em pacientes pediátricos críticos considerando o ambiente de UTI e mobilidade precoce.

14 Fev, 2022 | 16:00h

2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility – Pediatric Critical Care Medicine

 

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Critérios para sepse pediátrica – Revisão sistemática e metanálise da Pediatric Sepsis Definition Taskforce.

8 Fev, 2022 | 14:41h

Criteria for Pediatric Sepsis—A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce – Critical Care Medicine

 

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Em pacientes pediátricos mecanicamente ventilados, um estudo observacional mostrou uma ampla variação, entre hospitais, do uso de culturas de aspirado endotraqueal, e taxas mais altas foram correlacionadas a uso aumentado de antibióticos.

4 Fev, 2022 | 16:18h

Association of Endotracheal Aspirate Culture Variability and Antibiotic Use in Mechanically Ventilated Pediatric Patients – JAMA Network Open

 

Comentário da autora no Twitter (fio – clique para saber mais)

 

Revisão sistemática | Cursos breves de antibióticos intravenosos para infecções urinárias em crianças pequenas.

28 Jan, 2022 | 15:12h

Short Intravenous Antibiotic Courses for Urinary Infections in Young Infants: A Systematic Review – Pediatrics (link para o resumo – $ para o texto completo)

Estudo randomizado | Lidocaína spray pode reduzir a dor durante a punção da artéria radial.

21 Jan, 2022 | 15:21h

Effectiveness of lidocaine spray on radial arterial puncture pain: A randomized double-blind placebo controlled trial – The American Journal of Emergency Medicine (link para o resumo – $ para o texto completo)

Consenso de especialistas para a prática de transfusão de plasma e plaquetas em crianças com doença crítica.

20 Jan, 2022 | 22:43h

Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB) – Pediatric Critical Care Medicine

Estudo randomizado | Em crianças com pneumonia adquirida na comunidade, antibioticoterapia ambulatorial por 5 dias resultou em taxas de resposta clínica similares às obtidas com a estratégia padrão de 10 dias.

20 Jan, 2022 | 22:04h

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics (gratuito por tempo limitado)

Comentários:

Trial finds 5 days of antibiotics superior to 10 for kids with pneumonia – CIDRAP

Shorter antibiotics treatment is better for young children with outpatient pneumonia – Vanderbilt University Medical Center

Conteúdos relacionados:

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review – short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

Revisão | Tratamento da síndrome inflamatória multissistêmica (MIS-C) em crianças e adolescentes.

20 Jan, 2022 | 21:27h

Treatment of MIS-C in Children and Adolescents – Current Pediatrics Reports

Ver também: Clinical practice guidelines in multisystem inflammatory syndrome (MIS-C) related to COVID-19: a critical review and recommendations – World Journal of Pediatrics

Conteúdos relacionados:

Review of 4,470 cases of Multisystem Inflammatory Syndrome in Children in the US.

WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19.

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Estudo randomizado | Em neonatos a termo e próximos do termo, tratamento medicamentoso de todas as convulsões detectadas por meios clínicos e eletrográficos não foi associado com menores taxas de morte ou incapacidade em 2 anos, em comparação com o tratamento apenas das convulsões clinicamente detectadas.

13 Jan, 2022 | 20:54h

Effect of Treatment of Clinical Seizures vs Electrographic Seizures in Full-Term and Near-Term Neonates: A Randomized Clinical Trial – JAMA Network Open

Comentários:

Should we treat electrographic seizures? – Neonatal Research

Subclinical Electrographic Seizures in the Newborn—Is More Treatment Better? – JAMA Network Open

Neonatal Seizures: Little Difference Between EEG/Clinical Treatment – Physician’s Weekly

 

Comentário no Twitter

 

Estudo internacional identifica preditores de desfechos graves em crianças com COVID-19.

13 Jan, 2022 | 12:09h

Comunicado de imprensa: International study identifies predictors of severe outcomes in children with COVID-19 – University of Calgary

Estudo original: Outcomes of SARS-CoV-2–Positive Youths Tested in Emergency Departments: The Global PERN–COVID-19 Study – JAMA Network Open

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