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Emergências e Terapia Intensiva

Estudo randomizado | Combinação de anticorpos REGEN-COV subcutâneos evitou infecção sintomática por Covid-19 em contactantes de pessoas infectadas.

5 Ago, 2021 | 11:57h

Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 – New England Journal of Medicine

Conteúdos relacionados:

RCT: Bamlanivimab plus Etesevimab reduce mortality and hospitalization in ambulatory patients with early Covid-19 (within 3 days of a positive test) who are at risk for clinical deterioration (i.e., older people, obese, diabetics, immunocompromised, with CV disease).

[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response.

 

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Miocardite e pericardite após vacinação contra COVID-19.

5 Ago, 2021 | 11:53h

Myocarditis and Pericarditis After Vaccination for COVID-19 – JAMA

Conteúdos relacionados:

Analysis finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis.

CDC: Use of mRNA COVID-19 vaccine after reports of myocarditis among vaccine recipients – “Continued use of mRNA COVID-19 vaccines in all recommended age groups will prevent morbidity and mortality from COVID-19 that far exceed the number of cases of myocarditis expected”.

Case Series: Myocarditis following immunization with mRNA COVID-19 vaccines.

CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.

Estudo randomizado | Desfechos similares entre milrinona e dobutamina no tratamento do choque cardiogênico.

5 Ago, 2021 | 11:40h

Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Resumo visual: Milrinone vs. Dobutamine in Cardiogenic Shock

Comentário: Inotrope Showdown Leaves No Winner in Cardiogenic Shock – MedPage Today (link para o resumo – $ para o texto completo)

Posicionamento Científico | Abordagem perioperatória de pacientes cirúrgicos pós-COVID-19.

4 Ago, 2021 | 12:35h

Perioperative management of post-COVID-19 surgical patients: Indian Society of Anaesthesiologists (ISA National) Advisory and Position Statement – Indian Journal of Anaesthesia

Conteúdos relacionados:

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

WSES Position Paper: The management of surgical patients in the emergency setting during COVID-19 pandemic

Preparing previously COVID-19-positive patients for elective surgery: A framework for preoperative evaluation

 

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Gestão de antimicrobianos na UTI em tempos de COVID.

4 Ago, 2021 | 12:31h

Antimicrobial stewardship in the ICU in COVID times: the known unknowns – International Journal of Antimicrobial Agents

Conteúdos relacionados:

IDSA Updated Covid-19 Guidance: Co-Infection and Antimicrobial Stewardship – “bacterial coinfections with SARS-CoV-2 infection are relatively infrequent (likely occurring in less than 10% of hospitalized COVID-19 patients)”.

Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s?

Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.

Too many COVID-19 patients get unneeded ‘just in case’ antibiotics

Pneumomediastino espontâneo em pacientes diagnosticados com Covid-19: uma série de casos com revisão da literatura.

4 Ago, 2021 | 12:29h

Spontaneous Pneumomediastinum in Patients Diagnosed with COVID-19: a Case Series with Review of Literature – Academic Radiology

Recomendações de prática clínica sobre a abordagem da parada cardíaca perioperatória.

4 Ago, 2021 | 12:20h

Clinical practice recommendations on the management of perioperative cardiac arrest: A report from the PERIOPCA Consortium – Critical Care

M-A | Suporte respiratório não invasivo fora da unidade de terapia intensiva para insuficiência respiratória aguda relacionada a Covid-19.

3 Ago, 2021 | 11:35h

Noninvasive respiratory support outside the intensive care unit for acute respiratory failure related to coronavirus-19 disease: a systematic review and meta-analysis – Critical Care

Covid: especialistas afirmam que oxímetros de pulso não funcionam tão bem em pele mais escura.

3 Ago, 2021 | 11:28h

Covid: Pulse oxygen monitors work less well on darker skin, experts say – BBC

Conteúdos relacionados:

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias

“Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients

Atualização 2021 sobre diagnóstico e tratamento de síndromes coronarianas agudas no perioperatório.

3 Ago, 2021 | 11:16h

2021 Update in the Diagnosis and Management of Acute Coronary Syndromes For the Perioperative Clinician – Journal of Cardiothoracic and Vascular Anesthesia

 

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