Emergências e Terapia Intensiva

Perspectiva | Lições de vida após uma carreira médica na terapia intensiva.

10 Nov, 2021 | 12:33h

Life lessons after a career in intensive care medicine – Intensive Care Medicine

 

Comentário no Twitter

Reflections/lessons from a life in #ICU:
1⃣work with people you like/love
2⃣take sabbaticals to recharge
3⃣prioritize family = those you love most
4⃣live every day as having terminal disease: focus on what most important@JRandallCurtis1 #ICMfromtheInsidehttps://t.co/X2GKXRM3rf pic.twitter.com/ytx1eMLkMW

— Intens Care Med (@yourICM) November 8, 2021

 

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M-A | Em adultos com sepse ou choque séptico, ressuscitação metabólica com vitamina C, glicocorticoides, vitamina B1 ou a combinação desses medicamentos não foi associada com redução na mortalidade no longo prazo. Embora sem redução na mortalidade, a adição de glicocorticoides a outros tratamentos encurtou a duração da terapia vasopressora e da internação em UTI.

10 Nov, 2021 | 12:31h

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Conteúdos relacionados:

Sepsis treatment: Another trial shows no benefit from the combination of Vitamin C, Thiamine, and Hydrocortisone

The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis

 

Comentário no Twitter

Metabolic resuscitation in sepsis/septic shock with
💉vitamin C
💉glucocorticoids
💉vitamin B1
or their combinations not proven to⬇️long-term mortality.
NMA suggests association high dose/very high dose vit C & decreased mortality (low certainty).#FOAMcc https://t.co/tB2KKRjtzc pic.twitter.com/uns9rcmDbA

— Intens Care Med (@yourICM) November 9, 2021

 

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Revisão | Encefalopatia urêmica.

10 Nov, 2021 | 12:29h

Uremic Encephalopathy – Kidney International

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Revisão prática | Diagnósticos rápidos de COVID-19.

9 Nov, 2021 | 12:27h

COVID-19 rapid diagnostics: practice review – Emergency Medicine Journal

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Comunicado de imprensa – ainda não publicado] Estudo randomizado | Novo antiviral oral da Pfizer, candidato a tratamento da Covid-19, reduziu o risco de internação ou morte em 89% em análise interina da fase 2/3 do estudo EPIC-HR.

8 Nov, 2021 | 12:47h

Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR Study

Comentários:

Expert reaction to press release from Pfizer giving interim analysis of their Phase 2/3 EPIC-HR study of PAXLOVID™ in non-hospitalized high-risk adults with COVID-19 – Science Media Centre

Pfizer’s Good News Is the World’s Good News – Science

Experimental Pfizer pill prevents Covid hospitalizations and deaths – STAT

Pfizer Says New Anti-Viral Drug Combination Cuts Risks Of Serious COVID-19 By 89% – Health Policy Watch

Pfizer reports good results against severe COVID-19 for its antiviral pill – CIDRAP

Covid: Pfizer says antiviral pill 89% effective in high-risk cases – BBC

Pfizer says COVID-19 pill cut hospital, death risk by 90% – Associated Press

Pfizer’s COVID-19 pill treatment reduces risk of being hospitalized or dying by 89%, company says – ABC News

 

Comentário no Twitter (fio – clique para saber mais)

Pfizer’s oral protease inhibitor PF-07321332 for #COVID19 Reduced Risk of Hospitalization or Death from 6.7% (41/612) to 1.0% (6/607) when starting within 5 days of symptom onset.
10 vs 0 deaths. #idtwitter https://t.co/ZAIm6Y5mAt

— David Boulware, MD MPH (@boulware_dr) November 5, 2021

 

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Novo estudo desafia a ideia de que um escore de cálcio de zero seja suficiente para descartar obstrução coronariana em pacientes sintomáticos, sobretudo em adultos jovens.

8 Nov, 2021 | 12:25h

Association of Age With the Diagnostic Value of Coronary Artery Calcium Score for Ruling Out Coronary Stenosis in Symptomatic Patients – JAMA Cardiology (link para o resumo – $ para o texto completo)

Comentário: Zero CAC Questionable for Ruling Out Obstructive CAD in Young Adults – TCTMD

 

Comentário do autor no Twitter (fio – clique para saber mais)

There has been a lot of discussion about our recent paper in JAMA Cardiology. In my opinion, much of the discussion is caused by a troublesome extrapolation of the results to the value of CAC in risk assessment in primary prevention. I will go through our findings in these tweets https://t.co/O0Rl12XYmV

— Martin Bødtker Mortensen (@MaBMortensen) November 1, 2021

 

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Coisas que fazemos sem nenhum motivo: prescrever tramadol para dor em pacientes internados.

5 Nov, 2021 | 17:05h

Conteúdos relacionados:

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Diretriz ASH emite recomendação condicional contra o uso rotineiro de anticoagulação profilática ambulatorial em pacientes com COVID-19 depois da alta hospitalar.

4 Nov, 2021 | 12:03h

American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: July 2021 update on post-discharge thromboprophylaxis – Blood Advances

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Revisão | O papel da imagem torácica no diagnóstico, tratamento e monitoramento da Covid-19.

3 Nov, 2021 | 11:12h

The role of chest imaging in the diagnosis, management, and monitoring of coronavirus disease 2019 (COVID-19) – Insights into Imaging

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Revisão | Lesão cardíaca na Covid-19.

3 Nov, 2021 | 11:10h

Cardiac injury in COVID-19 – Intensive Care Medicine

 

Comentário no Twitter

Myocardial injury in #COVID19, many potential mechanisms:
🫀myocardial DO2/VO2 imbalance
🫀ARDS & MV
🫀cytokine storm
🫀direct viral lesion.
Variable clinical presentations, with high complications rates, mortality & risk of long-term cardiac impairment.https://t.co/wxPDDrtEoY pic.twitter.com/vOx1B4cwY2

— Intens Care Med (@yourICM) November 2, 2021

 

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