Emergências e Terapia Intensiva

Uma abordagem baseada em árvore de decisão para acesso a vias aéreas no algoritmo de 2022 para via aérea difícil da American Society of Anesthesiologists.

22 Fev, 2022 | 14:18h

A Decision Tree Approach to Airway Management Pathways in the 2022 Difficult Airway Algorithm of the American Society of Anesthesiologists – Anesthesia & Analgesia

Artigo original: 2022 ASA Guidelines for Management of the Difficult Airway.

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Atualização clínica sobre medicações vasoativas no tratamento do choque cardiogênico.

22 Fev, 2022 | 14:16h

A Clinical Update on Vasoactive Medication in the Management of Cardiogenic Shock – Clinical Medicine Insights: Cardiology

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Bioterrorismo: uma análise dos agentes biológicos usados em ataques terroristas.

19 Fev, 2022 | 13:44h

Bioterrorism: An analysis of biological agents used in terrorist events – The American Journal of Emergency Medicine

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Arritmias em mulheres: incidência, apresentação e tratamento.

19 Fev, 2022 | 13:43h

Arrhythmias in Female Patients: Incidence, Presentation and Management – Circulation Research (gratuito por tempo limitado)

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M-A | Em pacientes com ataque isquêmico transitório (AIT), o encaminhamento para uma clínica de AIT pode propiciar uma investigação urgente e o início das medidas preventivas pode ser tão efetivo quanto cuidar do paciente internado.

19 Fev, 2022 | 13:42h

Risk of Subsequent Stroke Among Patients Receiving Outpatient vs Inpatient Care for Transient Ischemic Attack: A Systematic Review and Meta-analysis – JAMA Network Open

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Estudo randomizado | Nirmatrelvir oral para adultos de alto risco com Covid-19 reduz em 89% o risco de internação.

17 Fev, 2022 | 15:37h

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Entrevista em áudio: A New Antiviral against Covid-19 – new England Journal of Medicine

Conteúdos relacionados:

[Press release – not published yet] Pfizer’s Covid pill remains 89% effective for reducing the risk of hospitalization or death in final analysis.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

 

Comentário no Twitter

The Paxlovid pill (Nirmatrelvir) randomized, placebo-controlled trial published @NEJM:
89% efficacy vs Covid hospitalizations or deaths, and quick reduction of viral load.
The active pills had less serious adverse events or discontinuations than placebohttps://t.co/HBMRZt4wBo pic.twitter.com/LDQv41O56c

— Eric Topol (@EricTopol) February 16, 2022

 

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Revisão | Diagnóstico e tratamento de síndromes coronarianas agudas.

17 Fev, 2022 | 15:29h

Diagnosis and Treatment of Acute Coronary Syndromes: A Review – JAMA (gratuito por tempo limitado)

Revisão clínica em áudio: Diagnosis and Treatment of Acute Coronary Syndromes – JAMA

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Posicionamento científico SIMEU sobre suporte respiratório não invasivo na pneumonia por COVID-19.

17 Fev, 2022 | 15:28h

SIMEU position paper on non-invasive respiratory support in COVID-19 pneumonia – Internal and Emergency Medicine

Conteúdos relacionados:

RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy.

RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy.

Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of non-invasive ventilation over high-flow nasal oxygen in reducing the need for intubation”.

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Revisão sistemática | Tratamento do primeiro estágio de estado epiléptico convulsivo em adultos.

17 Fev, 2022 | 15:11h

Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence – Journal of Neurology

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Perda de visão central vs. periférica na medicina de emergência.

17 Fev, 2022 | 15:07h

Central vs. Peripheral Vision Loss – emDocs

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