Destaques

Shocking!
99% – or almost the entire world's population breathes air with unhealthy levels of fine particulate matter & nitrogen dioxide, and threatens their health.
More: https://t.co/Llaj2wHk0V #HealthierTomorrow pic.twitter.com/QlHUP4iyS4

— World Health Organization (WHO) (@WHO) April 4, 2022

#ACC22 – Estudo randomizado | Em pacientes submetidos a cirurgia não cardíaca, uma estratégia de aquecimento intraoperatório agressivo (temperatura alvo de 37 °C) não reduziu as complicações maiores em comparação com a rotina de tratamento térmica (alvo de 35,5 °C).

6 Abr, 2022 | 12:58h

Aggressive intraoperative warming versus routine thermal management during non-cardiac surgery (PROTECT): a multicentre, parallel group, superiority trial – The Lancet (necessário cadastro gratuito)

Comentário: PROTECT: Aggressive Warming During Surgery Does Not Reduce Major Complications – American College of Cardiology

Diretriz de consenso | Definição, diagnóstico e tratamento da mucormicose pulmonar associada a COVID-19.

6 Abr, 2022 | 12:57h

Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India – The Lancet Infectious Diseases

Revisão sistemática | Videolaringoscopia vs. laringoscopia direta para adultos submetidos a entubação traqueal.

6 Abr, 2022 | 12:55h

Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation – Cochrane Library

Comentário do autor no Twitter (fio – clique para saber mais)

1/ We just published our full @Cochrane_ACE systematic review and meta-analysis of videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation.

The full review is here, but first – some of our key takeaways 👇https://t.co/HxzXhF83ZB

— Jan Hansel (@VirtueOfNothing) April 4, 2022

Seminário | Síndromes coronarianas agudas.

6 Abr, 2022 | 12:54h

Acute coronary syndromes – The Lancet (gratuito por tempo limitado)

Comentário no Twitter

Despite substantial progress in the diagnosis & treatment of acute coronary syndromes, cardiovascular disease remains the leading cause of death globally.

This new Seminar provides a clinical overview & describes key scientific advances. https://t.co/jRHmVWmVX0

— The Lancet (@TheLancet) April 2, 2022

Perspectiva | As evidências sobre a 4ª dose das vacinas contra Covid & a questão complicada dos limites de idade.

6 Abr, 2022 | 12:53h

The Evidence On 4th Doses of Covid Vaccines & the Thorny Question of Age Thresholds – Absolutely Maybe Blog, by Hilda Bastian

Conteúdos relacionados:

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

Comentário no Twitter

The evidence on 4th doses of Covid vaccines & the thorny question of age thresholds – 50? 55? 60? 65? 70? 75? 80? Each has been set by at least one country… | New @PLOS https://t.co/4tJ0o1fUC1

— Hilda Bastian, PhD (@hildabast) April 1, 2022

Estudo de coorte | Níveis séricos elevados de sódio na meia-idade (pode haver correlação com baixa ingestão hídrica) estão associados a risco aumentado de hipertrofia ventricular e insuficiência cardíaca após 25 anos de seguimento.

6 Abr, 2022 | 12:51h

Middle age serum sodium levels in the upper part of normal range and risk of heart failure – European Heart journal (link para o resumo – $ para o texto completo)

Comunicado de imprensa: Good hydration may reduce long-term risks for heart failure – Serum sodium levels may help identify adults with a greater chance of experiencing heart disease. – National Institutes of Health

Estudo randomizado | Roxadustate oral vs. epoietina alfa no tratamento de anemia em pacientes sob diálise para doença renal crônica.

Revisão e M-A | Reabilitação pulmonar pós-Covid.

Estudo de coorte e metanálise atualizada | Alto consumo de ovos e de colesterol na dieta está ligado a risco aumentado de mortalidade geral e por doenças cardiovasculares.

Bilhões de pessoas ainda respiram um ar não saudável: novos dados da OMS.