Destaques

Reduzindo o SARS-CoV-2 em ambientes fechados compartilhados.

14 Jun, 2022 | 13:57h

Reducing SARS-CoV-2 in Shared Indoor Air – JAMA

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M-A | Eficácia e segurança da anticoagulação profilática padrão vs. intensificada em pacientes com Covid-19.

14 Jun, 2022 | 13:56h

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Conteúdos relacionados:

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 

Comentário no Twitter

🆕💥💥Systematic review & meta-analysis @OFIDJournal Intensified anticoagulation has NO effect on mortality among hospitalised #COVID19 & ⬆️bleeding
Possible signal of mortality reduction for non-ICU patients although with low precision& high heterogeneity https://t.co/OqLYScxK53

— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) June 7, 2022

 

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M-A | Eficácia e danos do tocilizumabe no tratamento de pacientes com COVID-19.

14 Jun, 2022 | 13:54h

Efficacy and harms of tocilizumab for the treatment of COVID-19 patients: A systematic review and meta-analysis – PLOS One

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Diretriz de posicionamento sobre criminalização do erro médico e chamado para ação visando a prevenir danos ao paciente.

14 Jun, 2022 | 13:25h

Position Statement on Criminalization of Medical Error and Call for Action to Prevent Patient Harm from Error – Anesthesia Patient Safety Foundation

Comentário: Anesthesiologist Group Says Hospitals Can Prevent Fatal Errors Like Vanderbilt’s — Feds said Vaught wasn’t the only one who erred; hospital had four “immediate jeopardy” flaws – MedPage Today (necessário cadastro gratuito)

Conteúdos relacionados:

ECRI and ISMP PUBLIC STATEMENT | Medication Errors are Complex; Criminal Charges Will Not Improve Care – Institute for Safe Medication Practices

ISMP Speaks Out Against Criminalization of Medication Errors – Institute for Safe Medication Practices

The simple thing hospitals can do to prevent dangerous drug mistakes – CNN

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Revisão sistemática | Produtos feitos à base de Cannabis para dor crônica.

14 Jun, 2022 | 13:24h

Cannabis-Based Products for Chronic Pain: A Systematic Review – Annals of Internal Medicine

Resumo dos anais em vídeo: Cannabis-Based Products for Chronic Pain: A Systematic Review

Resumo para pacientes: Cannabis-Based Products for Chronic Pain

Conteúdos relacionados:

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

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Combinação de infusões de anticorpos anti-HIV suprimem o vírus por período prolongado.

14 Jun, 2022 | 13:21h

Comunicado de imprensa: Combination anti-HIV antibody infusions suppress virus for prolonged period – National Institutes of Health

Estudo original: Combination anti-HIV antibodies provide sustained virological suppression – Nature

 

Comentários no Twitter

Still don't get the enthusiasm for HIV Rx with bNAbs.
Compared to existing antivirals, they have:
– more baseline resistance
– the need to scale up new resistance tests
– more resource requirements (IV administration)
– … and, if like other monoclonals, $$$
What am I missing? https://t.co/7WZmIjutwE

— Paul Sax (@PaulSaxMD) June 1, 2022

This is a wonderful advance.

"Our data demonstrate that combination therapy with broadly neutralizing monoclonal antibodies can provide long-term virological suppression without antiretroviral therapy in individuals with HIV"https://t.co/DKNVSlg3mC

— Michael Worobey (@MichaelWorobey) June 2, 2022

 

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Revisão de escopo | Consequências não intencionais das medidas implementadas no ambiente escolar para conter a pandemia de COVID-19.

14 Jun, 2022 | 13:20h

Unintended consequences of measures implemented in the school setting to contain the COVID‐19 pandemic: a scoping review – Cochrane Library

Resumo: Unintended consequences of school-based measures to manage the COVID-19 pandemic – Cochrane Library

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Avaliação prospectiva da disfunção autonômica em pacientes com sequela pós-aguda de COVID-19.

14 Jun, 2022 | 13:18h

Prospective Evaluation of Autonomic Dysfunction in Post-Acute Sequela of COVID-19 – Journal of the American College of Cardiology

Comentário: Autonomic Dysfunction in Post-Acute Sequela of COVID-19 – American College of Cardiology

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Metanálise com dados de pacientes individuais | Indicadores prognósticos e desfechos de pacientes internados por COVID-19 com doença neurológica.

14 Jun, 2022 | 13:17h

Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis – PLOS One

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Predição da resposta a fluidos. Quais são as novidades?

14 Jun, 2022 | 13:15h

Prediction of fluid responsiveness. What’s new? – Annals of Intensive Care

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