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#CCR22 – Estudo randomizado | Vitamina C intravenosa aumenta o risco de morte ou disfunção persistente de órgão em adultos com sepse em UTI.

19 Jun, 2022 | 17:03h

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit – New England Journal of Medicine

Conteúdos relacionados:

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA

 

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#CCR22 – Estudo randomizado | Terapia com cânula nasal de alto fluxo atinge critério de não inferioridade em comparação ao CPAP na liberação do suporte respiratório em crianças criticamente doentes em UTI.

19 Jun, 2022 | 17:01h

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

 

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#CCR22 – Estudo randomizado | Entre pacientes críticos submetidos a intubação traqueal, administrar 500 mL de fluido em bolus não diminui a incidência de hipotensão arterial grave, parada cardíaca ou morte.

19 Jun, 2022 | 16:59h

Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

 

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Perspectiva | Vírus que estiveram em pausa durante a Covid estão de volta – e se comportando de maneiras inesperadas.

19 Jun, 2022 | 16:58h

Viruses that were on hiatus during Covid are back — and behaving in unexpected ways – STAT

Diretriz científica AHA | Em direção a uma melhor compreensão das diferenças relacionadas a sexo e gênero no tratamento endovascular do AVC.

19 Jun, 2022 | 15:55h

Toward a Better Understanding of Sex- and Gender-Related Differences in Endovascular Stroke Treatment: A Scientific Statement From the American Heart Association/American Stroke Association – Stroke

Comunicado de imprensa: More data needed on stroke treatment and outcomes by sex, gender – American Heart Association

 

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“Discriminatório e estigmatizante”: cientistas pressionam para que o vírus da varíola dos macacos seja renomeado.

19 Jun, 2022 | 15:52h

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Ver também: Rename monkeypox strains to remove geographic stigma, researchers say – Science

Conteúdos relacionados:

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

Revisão | Tratamento da sepse para o nefrologista.

19 Jun, 2022 | 15:50h

Sepsis Management for the Nephrologist – Clinical Journal of the American Society of Nephrology

Estudo da Pfizer sobre o Paxlovid falha em responder a questões centrais sobre o benefício para populações mais amplas.

19 Jun, 2022 | 15:46h

Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations – STAT

Estudo randomizado | Efetividade e segurança de loções, cremes, géis e pomadas emolientes para eczema infantil.

19 Jun, 2022 | 15:45h

Effectiveness and safety of lotion, cream, gel, and ointment emollients for childhood eczema: a pragmatic, randomised, phase 4, superiority trial – The Lancet Child & Adolescent Health

Comunicado de imprensa: The right moisturiser for children with eczema is the one that they like to use, study finds – University of Nottingham

Comentário: Lotion, Cream, Gel, and Ointment Similarly Effective for Childhood Eczema – HealthDay

 

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Estudo randomizado | Efeito da vareniclina adicionada ao aconselhamento sobre cessação do tabagismo entre fumantes afroamericanos.

19 Jun, 2022 | 15:42h

Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial – JAMA Network Open

Editorial: Helping African American Individuals Quit Smoking: Finally, Some Progress – JAMA

Comunicado de imprensa: Varenicline Increases Smoking Cessation Rates for African American Smokers – University of Kansas Cancer Center

 

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