Destaques
M-A de estudos randomizados | Acetato de megestrol não é benéfico para a anorexia/caquexia relacionada ao câncer.
18 Jul, 2022 | 12:53h
Estudo randomizado | Trombectomia endovascular isoladamente NÃO é não inferior à ponte trombolítica padrão associada a trombectomia endovascular dentro de 4,5 horas do início do AVC.
14 Jul, 2022 | 12:05hEndovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)
Estudo relacionado: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)
Comentário no Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
Estudo randomizado | Trombectomia isolada NÃO é não inferior a alteplase intravenosa com trombectomia em pacientes com AVC.
14 Jul, 2022 | 12:04hThrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)
Estudo relacionado: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)
Comentário no Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
Estudo randomizado | Inibição de miosina em pacientes com cardiomiopatia hipertrófica obstrutiva encaminhados para terapia de redução de septo.
14 Jul, 2022 | 12:02hConteúdo relacionado: #ACC22 [Not published yet] – RCT: Mavacamten reduces the need for surgical intervention in patients with obstructive hypertrophic cardiomyopathy.
Tratamento da febre em adultos: revisão sistemática com metanálise e análises de estudos sequenciais.
14 Jul, 2022 | 12:01h
Modelos de predição clínica para mortalidade em pacientes com Covid-19: validação externa e metanálise de dados individuais de participantes.
14 Jul, 2022 | 11:59h
M-A | Oxigênio domiciliar para hipoxemia moderada na doença pulmonar obstrutiva crônica.
14 Jul, 2022 | 11:58hHome oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link para o resumo – $ para o texto completo)
Comentário no Twitter
Home oxygen probably makes little or no difference to 3-year mortality in pts with #COPD and moderate hypoxaemia
Systematic review & meta-analysis from Yves Lacasse & colleagues https://t.co/8wDrkEd1LH pic.twitter.com/UoOqW7hngT
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
Estudo randomizado | Dieta neutropênica vs. regular para quimioterapia de indução na leucemia aguda.
14 Jul, 2022 | 11:57hNeutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial – BMJ Supportive & Palliative Care (link para o resumo – $ para o texto completo)
Conteúdos relacionados:
Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer – European Journal of Cancer (link para o resumo – $ para o texto completo)
Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis – BMJ Supportive & Palliative Care (link para o resumo – $ para o texto completo)
Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (PDF)
Estudo de coorte | Risco e tempo de cirurgia não cardíaca após implante de válvula aórtica transcateter.
14 Jul, 2022 | 11:55hComentários:
Surgery After TAVR: Waiting a Month or More Not Really Better— Prosthesis-patient mismatch, paravalvular regurgitation the bigger issues for surgical candidates – MedPage Today (necessário cadastro gratuito)
Comentários no Twitter
In this cohort study, noncardiac surgery (NS) after transcatheter aortic valve implantation (TAVI) was not associated with more perioperative adverse events. Suboptimal device performance was associated with increased risk of adverse outcomes after NS. https://t.co/OYSLECeOzt
— JAMA Network Open (@JAMANetworkOpen) July 7, 2022
Interesting analysis of 300 pts undergoing NCS after TAVI: NCS may be performed early (<30d) after successful TAVI. Suboptimal device performance (prosthesis-pt mismatch, paravalvular regurg) was associated with incr risk
Risk and Timing of NCS After TAVI https://t.co/ILS3YBFcyz— Steven Cohn, MD (@preopconsult) July 10, 2022
Resumo de diretriz ADA | Obesidade e gerenciamento do peso para prevenção e tratamento do diabetes tipo 2.
13 Jul, 2022 | 12:31hObesity and Weight Management for Prevention and Treatment of Type 2 Diabetes – JAMA (gratuito por tempo limitado)
Diretriz original: ADA 2022 Standards of Medical Care in Diabetes – American Diabetes Association