Destaques

M-A | Prevalência e incidência globais do zumbido.

10 Ago, 2022 | 14:40h

Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis – JAMA Neurology (gratuito por tempo limitado)

Comentário: Review: Global Pooled Prevalence of Tinnitus 14.4 Percent – HealthDay

 

Comentário no Twitter

The global burden of #tinnitus is large, similar to #migraine and pain, and the lack of effective treatment options justifies a major investment in research in this area. https://t.co/9uVJmnYh9c

— JAMA Neurology (@JAMANeuro) August 8, 2022

 

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Estudo randomizado | Fechamento abdominal Hughes vs. fechamento de padrão para reduzir hérnias incisionais após cirurgia de câncer colorretal.

10 Ago, 2022 | 14:39h

Hughes abdominal closure versus standard mass closure to reduce incisional hernias following surgery for colorectal cancer: the HART RCT – Health Technology Assessment

 

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Sinopse de diretriz | Tratamento da infecção por Clostridioides difficile.

10 Ago, 2022 | 14:38h

Treatment of Clostridioides difficile Infection – JAMA (gratuito por tempo limitado)

Diretriz original: ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections – American Journal of Gastroenterology

Diretrizes relacionadas:

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults – Clinical Infectious Diseases

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases – International Journal of Infectious Diseases

Clostridioides difficile infection: antimicrobial prescribing – National Institute for Health and Care Excellence

Japanese Clinical Practice Guidelines for Management of Clostridioides (Clostridium) difficile infection – Journal of Infection and Chemotherapy

 

Comentário no Twitter

A summary of @AmCollegeGastro’s 2021 guidelines on treatment of Clostridioides difficile infection. https://t.co/QzrMa71ttu

— JAMA (@JAMA_current) August 8, 2022

 

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Interpretação de teste diagnóstico | Cistatina C para estimar a taxa de filtração glomerular.

10 Ago, 2022 | 14:36h

Serum Cystatin C for Estimation of GFR – JAMA (gratuito por tempo limitado)

 

Comentário no Twitter

An 80-year-old man with #type2diabetes and #hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his ACE inhibitor. #JAMADiagnosticTestInterpretation https://t.co/kxg0yHeGUr

— JAMA (@JAMA_current) August 8, 2022

 

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Diretriz clínica ACG | Gastroparesia.

9 Ago, 2022 | 17:38h

ACG Clinical Guideline: Gastroparesis – The American Journal of Gastroenterology

Conteúdos relacionados: United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis – UEG Journal

 

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Diretriz de posicionamento | Uso de albumina na cirrose hepática.

9 Ago, 2022 | 17:36h

Position statement on the use of albumin in liver cirrhosis – Annals of Hepatology

 

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Estudo randomizado | Efeito da semaglutida 1 vez/semana vs. insulina aspart 3 vezes/dia, ambas adicionadas à metformina e ao tratamento otimizado com insulina glargina em participantes com diabetes tipo 2.

9 Ago, 2022 | 17:34h

Effect of once-weekly semaglutide versus thrice-daily insulin aspart, both as add-on to metformin and optimized insulin glargine treatment in participants with type 2 diabetes (SUSTAIN 11): A randomized, open-label, multinational, phase 3b trial – Diabetes, Obesity and Metabolism

 

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Estudo randomizado | Agentes antissépticos cutâneos para prevenir infecção de sítio cirúrgico após cirurgia incisional.

9 Ago, 2022 | 17:33h

Antiseptic Skin Agents to Prevent Surgical Site Infection After Incisional Surgery: A Randomized, Three-armed Combined Non-inferiority and Superiority Clinical Trial (NEWSkin Prep Study) – Annals of Surgery (link para o resumo – $ para o texto completo)

Conteúdos relacionados:

Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials – The Lancet Infectious Diseases

Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial – The Lancet

 

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Dois estudos randomizados mostraram que anticorpos monoclonais não são melhores que placebo para doença de Parkinson.

9 Ago, 2022 | 17:31h

Estudo 1: Trial of Cinpanemab in Early Parkinson’s Disease – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Estudo 2: Trial of Prasinezumab in Early-Stage Parkinson’s Diseas – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentário: Monoclonal Antibodies No Better Than Placebo for Early Parkinson Disease – HealthDay

 

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Revisão sistemática | Impacto do rastreamento por tomografia computadorizada com baixa dose de radiação sobre a mortalidade relacionada a câncer de pulmão.

9 Ago, 2022 | 17:29h

Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality – Cochrane Library

Resumo: Impact of computed tomography (CT) on lung cancer screening – Cochrane Library

Conteúdos relacionados:

Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study – The BMJ

Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.

USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis

 

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