Destaques
Editorial | Mantendo as metanálises atuais.
29 Ago, 2022 | 17:17hKeeping Meta-analyses Fresh – JAMA Network Open
Estudo de coorte retrospectiva | Uso de nirmatrelvir e desfechos de Covid-19 grave durante o aumento da variante Ômicron.
29 Ago, 2022 | 17:16h
Comentário no Twitter
During the clinical rollout of nirmatrelvir in Israel in early 2022, most patients (78%) had previous SARS-CoV-2 immunity. Benefit was seen among patients at highest risk for Covid-19 progression, such as those 65+. https://t.co/O6CxzDdIfH pic.twitter.com/ccCaCCh15i
— NEJM (@NEJM) August 24, 2022
Hospitalizações por envenenamento não intencional por Cannabis entre crianças canadenses aumentou após a legalização.
29 Ago, 2022 | 17:15hEstudo original: Edible Cannabis Legalization and Unintentional Poisonings in Children – New England Journal of Medicine ($)
Declaração de recomendação USPSTF | Uso de estatinas para prevenção primária de doença cardiovascular em adultos.
29 Ago, 2022 | 16:49hEditoriais:
Relatório de evidência: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Entrevista com o autor: USPSTF Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults – JAMA
Página do paciente: Statins for the Prevention of Cardiovascular Disease – JAMA
Comentário: Latest statins guidance keeps more conservative approach to preventing first stroke or heart attack – CNN
Estudo randomizado | Em mulheres sob risco de parto prematuro, metade da dose antenatal de dexametasona NÃO foi não inferior à dose plena em relação aos desfechos neonatais.
29 Ago, 2022 | 16:47hNeonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial – The Lancet (link para o resumo – $ para o texto completo)
Comentário no Twitter
On 50th anniversary of Liggins & Howie's discovery of benefits of antenatal steroids for preterm birth, new study in @TheLancet confirms full dose (11.4 mg x 2) of betamethasone is necessary for optimum benefit. https://t.co/VgjtprM0W8#neoTwitter #obstetrics @EBNEO @ESPR_EBN pic.twitter.com/Cl1GbzWoRl
— Atul Malhotra (@Atul_Monash) August 19, 2022
Varíola dos macacos: atualização clínica para pediatras.
29 Ago, 2022 | 16:45hMonkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
Conteúdos relacionados:
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Adoçantes não nutritivos afetam microbiomas humanos e podem alterar respostas glicêmicas.
29 Ago, 2022 | 16:44hComunicado de imprensa: Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses – Cell Press
Estudo original: Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance – Cell
Comentário no Twitter
The skinny on non-nutritive sweeteners (they are not inert) via a randomized trial & gut #microbiome assessment: impact is individualized and can impair glycemic responsehttps://t.co/B7CUPy7tMf @CellCellPress @SuezLab @EranElinav @segal_eran @WeizmannScience @Yot_Coh @Elinav_Lab pic.twitter.com/Jz7lUkWlNr
— Eric Topol (@EricTopol) August 19, 2022
Estudo de coorte retrospectiva | Fatores de risco clínico e genético para tromboembolismo venoso incidental agudo em pacientes ambulatoriais com COVID-19.
29 Ago, 2022 | 16:42h
Comentário no Twitter
Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research
— JAMA Internal Medicine (@JAMAInternalMed) August 18, 2022
Estudo de coorte retrospectiva | Associação de COVID-19 vs. Influenza com risco de eventos trombóticos venosos e arteriais entre pacientes hospitalizados.
29 Ago, 2022 | 16:41hComentário: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP
Comunicado de imprensa: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News
Comentário no Twitter
The risk of blood clots in hospitalized patients with Covid vs influenza was increased 60-90% within 90 days, for venous but not arterial thrombosishttps://t.co/wPHf18NYYB @JAMA_current
Retrospective, much smaller influenza cohort from 2018-2019 pic.twitter.com/sClYHF0J6U— Eric Topol (@EricTopol) August 16, 2022
Resultados de longo prazo de um estudo randomizado | Vasopressina e metilprednisolona não melhoraram os desfechos em pacientes com parada cardíaca em ambiente hospitalar.
29 Ago, 2022 | 16:40h