Destaques

Oxigenação por membrana extracorpórea durante pandemias respiratórias: passado, presente e futuro.

13 Set, 2022 | 12:04h

Extracorporeal Membrane Oxygenation during Respiratory Pandemics: Past, Present, and Future – American Journal of Respiratory and Critical Care Medicine

 

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Estudo randomizado | Rezvilutamida vs. bicalutamida em combinação com terapia de deprivação androgênica em pacientes com câncer de próstata sensível a hormônio, metastático e de grande volume.

13 Set, 2022 | 12:03h

Rezvilutamide versus bicalutamide in combination with androgen-deprivation therapy in patients with high-volume, metastatic, hormone-sensitive prostate cancer (CHART): a randomised, open-label, phase 3 trial – The Lancet Oncology

Comentários:

Treatment options for metastatic hormone-sensitive prostate cancer – The Lancet Oncology

Rezvilutamide benefits shown in metastatic hormone-sensitive prostate cancer – medwire News

 

Comentário no Twitter

In a preplanned interim analysis of the phase III CHART trial in pts with high-volume mHSPC, rezvilutamide +ADT improve PFS (HR 0.44, 95% CI 0.33–0·.8; P<0.0001) & OS (HR 0.58, 95% CI 0.44–0.77]; P=0.0001) compared with bicalutamide + ADT: https://t.co/42IVnDUxfH #PCSM #uroonc

— NatureRevClinOncol (@NatRevClinOncol) September 7, 2022

 

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Estudo randomizado | Ordenha do sangue do cordão umbilical pode melhorar a saúde de bebês nascidos a termo não vigorosos e nascidos próximos ao termo.

12 Set, 2022 | 11:40h

Comunicado de imprensa: Umbilical cord milking may improve health in non-vigorous term and near-term infants – NIH News Releases

Estudo original: Umbilical cord milking in non-vigorous infants: A cluster-randomized crossover trial – American Journal of Obstetrics & Gynecology (link para o resumo – $ para o texto completo)

 

Comentário no Twitter

Does milking the umbilical cord benefit infants non-vigorous at birth?

A new RCT by @NeoAnup published in @AJOG_thegray evaluates this https://t.co/M5RRAzdEHz#neoEBM #neoTwitter #EBNEOAlerts pic.twitter.com/mZnSKjcGNt

— Evidence-Based Neo (@EBNEO) August 20, 2022

 

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Terapia anticoagulante oral com não antagonista de vitamina K precoce vs. tardia após AVC isquêmico agudo na fibrilação atrial: estudo de não inferioridade controlado e randomizado com base em registro.

12 Set, 2022 | 11:38h

Early Versus Delayed Non–Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Noninferiority Study – Circulation (gratuito por tempo limitado)

Conteúdo relacionado: Defining key design elements of registry-based randomised controlled trials: a scoping review – Trials

 

Comentário no Twitter

Congrats to my good friend/colleague @BoNorrving for the TIMING study! Starting NOAC after stroke d/t AF <4 d is safe (no ICH) and = or better than 5-10 d. Registry-based, pragmatic, investigator led, PROBE design. High value = science first approach.
https://t.co/35qiZ5Ivoa

— Dr. Lee Schwamm (@Braindoc_MGH) September 7, 2022

 

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Estudo sugere que muitos pacientes estáveis com infarto do miocárdio com elevação do segmento ST podem não precisar de internação de rotina em uma UTI cardíaca após reperfusão por intervenção coronariana percutânea.

12 Set, 2022 | 11:37h

Incidence and Predictors of Adverse Events Among Initially Stable ST‐Elevation Myocardial Infarction Patients Following Primary Percutaneous Coronary Intervention – Journal of the American Heart Association

 

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Estudo de coorte | Patologia cardíaca de longo prazo em indivíduos que tiveram COVID-19 inicialmente leve.

12 Set, 2022 | 11:36h

Long-term cardiac pathology in individuals with mild initial COVID-19 illness – Nature Medicine

 

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Revisão | COVID-19 em crianças.

12 Set, 2022 | 11:35h

COVID-19 in Children – Pediatric Clinics of North America

 

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Série Lancet | Síndrome da angústia respiratória aguda 2022.

8 Set, 2022 | 14:22h

Página principal: Acute Respiratory Distress Syndrome 2022 – The Lancet

Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

Opportunities for improved clinical trial designs in acute respiratory distress syndrome

Addressing the inequity of acute respiratory distress syndrome

 

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Opinião | Ácido tranexâmico para uma cirurgia mais segura: o momento é agora.

8 Set, 2022 | 14:21h

Tranexamic acid for safer surgery: the time is now – British Journal of Surgery

Conteúdos relacionados:

#ACC22 – RCT: Tranexamic acid reduces the risk of bleeding in patients undergoing noncardiac surgery.

Update on applications and limitations of perioperative tranexamic acid.

RCT | Effect of high- vs. low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery.

Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline

M-A: Intravenous tranexamic acid in surgical patients is not associated with increased risk of thromboembolic events and mortality

 

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Síndrome AVC-coração: avanços recentes e desafios.

8 Set, 2022 | 14:19h

Stroke–Heart Syndrome: Recent Advances and Challenges – Journal of the American Heart Association

 

Comentário no Twitter

Proud to share our updated review about the stroke-heart syndrome. Read more about recent advances on how brain ischemia can trigger cardiac events. https://t.co/ywJs2JbZht Many thanks to @SposatoL, @JohannesBacks and @Dr_No_Charite for your contribution! #brainheart #strokeheart pic.twitter.com/3IV9LU7fJN

— Jan Scheitz 🧠⚡️❤️ (@Jan_FriSch) September 3, 2022

Sob licença de Creative Commons Attribution‐Non Commercial‐No Derivs

 

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