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COVID-19 em pessoas com doenças reumáticas: riscos, desfechos e considerações de tratamento.

3 Mar, 2022 | 16:41h

COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations – Nature Reviews Rheumatology

 

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Miocardite após vacinação com BNT162b2 contra COVID-19 entre adolescentes em Hong Kong.

3 Mar, 2022 | 16:38h

Myocarditis Following COVID-19 BNT162b2 Vaccination Among Adolescents in Hong Kong – JAMA Pediatrics

Comentário: Study: Dosing change could reduce COVID-19 vaccine heart side effect in teens – UPI

Conteúdos relacionados:

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

Estudo randomizado | Em pacientes com câncer de pulmão em estágio inicial, lobectomia toracoscópica vídeo-assistida está associada com melhor recuperação da função física em 5 semanas em comparação com cirurgia aberta.

3 Mar, 2022 | 16:36h

Video-Assisted Thoracoscopic or Open Lobectomy in Early-Stage Lung Cancer – NEJM Evidence

 

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Estudo randomizado por cluster | Em adultos com parada cardíaca fora do hospital, a colocação de um dispositivo para via aérea supraglótico resultou em taxas similares de retorno da circulação espontânea em comparação à entubação orotraqueal.

2 Mar, 2022 | 11:45h

Effect of Placement of a Supraglottic Airway Device vs Endotracheal Intubation on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest in Taipei, Taiwan: A Cluster Randomized Clinical Trial – JAMA Network Open

Comentário: Cardiac Arrest Patients Don’t Necessarily Do Better With Intubation— Debate on prehospital advanced airway management continues – MedPage Today (necessário cadastro gratuito)

 

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Estudo randomizado | Artroscopia de quadril comparada com terapia personalizada para quadril em maiores de 16 anos com síndrome do impacto femoroacetabular.

2 Mar, 2022 | 11:43h

Resumo: Arthroscopic hip surgery compared with personalised hip therapy in people over 16 years old with femoroacetabular impingement syndrome: UK FASHIoN RCT – Health Technology Assessment

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Conteúdo relacionado: Randomized Trial: Arthroscopic Hip Surgery vs. Physiotherapy and Activity Modification for the Treatment of Femoroacetabular Impingement

Revisão JACC | Anticoagulação em pacientes com COVID-19.

2 Mar, 2022 | 11:42h

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Comentário: Review of Anticoagulation in Patients With COVID-19: Key Points – American College of Cardiology

Prescrição de nirmatrelvir-ritonavir para Covid-19: como reconhecer e administrar as interações medicamentosas.

2 Mar, 2022 | 11:40h

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

Conteúdos relacionados:

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

Pfizer antiviral pills may be risky with other medications – NBC News

The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist

Estudos sugerem que mercado de Wuhan foi o epicentro do início da pandemia.

2 Mar, 2022 | 11:38h

Wuhan market was epicentre of pandemic’s start, studies suggest – Nature

Conteúdos relacionados:

[Preprint] SARS-like viruses may jump from animals to people hundreds of thousands of times a year.

Did the coronavirus jump from animals to people twice? – Nature

The Origins of SARS-CoV-2: A Critical Review.

The animal origin of SARS-CoV-2 – “Trading of animals susceptible to bat coronaviruses is the likely cause of the COVID-19 pandemic”.

Fauci says natural origins theory of coronavirus is still the most likely.

 

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Diretriz atualizada da Joint British Diabetes Society for Inpatient Care | Tratamento da cetoacidose diabética em adultos.

1 Mar, 2022 | 15:41h

The management of diabetic ketoacidosis in adults—An updated guideline from the Joint British Diabetes Society for Inpatient Care

Diretriz atualizada | Momento da cirurgia eletiva e avaliação de risco após infecção por SARS-CoV-2 – “Mantemos a orientação de que os pacientes devem evitar cirurgias eletivas dentro de 7 semanas da infecção, a menos que os benefícios superem o risco de aguardar por tal período.”

1 Mar, 2022 | 15:38h

Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia

Conteúdos relacionados:

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

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