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Miocardite após 3ª dose de vacina da Pfizer em recrutas militares em Israel.

22 Mar, 2022 | 11:49h

Myocarditis Following a Third BNT162b2 Vaccination Dose in Military Recruits in Israel – JAMA

Conteúdos relacionados:

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.


Revisão | O desafio dos dogmas de tratamento sobre os quais as evidências são não existentes, fracas ou antigas.

22 Mar, 2022 | 11:48h

Challenging management dogma where evidence is non-existent, weak or outdated – Intensive Care Medicine (se o acesso a este link for pago, tente este)


Estudo randomizado | Eficácia e aceitação de terapias dietéticas na síndrome do intestino irritável sem constipação: um estudo randomizado comparando aconselhamento dietético tradicional, dietas de baixo FODMAP e dietas sem glúten.

22 Mar, 2022 | 11:46h

Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet and the Gluten-Free Diet – Clinical Gastroenterology and Hepatology

Comentário: Traditional Dietary Advice Optimal as an Irritable Bowel Syndrome Therapy – HCPLivre

Conteúdos relacionados:

10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.

Supplement: Irritable bowel syndrome and related conditions.

RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.

RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

Guidelines for the treatment of irritable bowel syndrome

ACG Clinical Guideline: Management of irritable bowel syndrome

M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome


Diretriz | Manejo de anticoagulantes e antiplaquetários durante sangramento gastrintestinal agudo e período periendoscópico.

21 Mar, 2022 | 16:38h

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period – Journal of the Canadian Association of Gastroenterology

 

Comentário no Twitter

 


Estudo sobre lesão cerebral traumática destaca desigualdade global quanto às causas e tratamento.

21 Mar, 2022 | 16:36h

Comunicado de imprensa: Largest ever study on traumatic brain injury highlights global inequality in causes and treatment – University of Cambridge

Estudo original: Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort stud – The Lancet Neurology


Mais dados sugerem que há riscos reduzidos de internação e morte causadas pela variante Ômicron do SARS-CoV-2 em comparação à variante Delta.

21 Mar, 2022 | 16:34h

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study – The Lancet

Comentário convidado: Omicron: fewer adverse outcomes come with new dangers – The Lancet

 

Comentário no Twitter

 


M-A | Posição prona para pacientes não entubados com insuficiência respiratória hipoxêmica aguda relacionada à COVID-19.

21 Mar, 2022 | 16:33h

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Comentário convidado: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine

Conteúdos relacionados:

[Preprint] RCT: In hypoxic but not critically ill patients with COVID-19, an intervention to increase prone positioning did not improve outcomes.

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required


Estudo mostra que não há risco aumentado de eventos neurológicos raros após vacinação contra Covid.

21 Mar, 2022 | 16:31h

Comunicado de imprensa: Study finds no increased risk of rare neurological events after covid vaccination – BMJ Newsroom

Estudo original: Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis – The BMJ

Editorial: The neurological safety of covid-19 vaccines


Uso da redução no risco absoluto para orientar a distribuição equitativa das vacinas contra COVID-19.

21 Mar, 2022 | 16:30h

Using absolute risk reduction to guide the equitable distribution of COVID-19 vaccines – BMJ Evidence-Based Medicine

Comunicado de imprensa: Researchers find equitable COVID-19 vaccine distribution can target risks in different geographical areas – University of New Mexico

 

Comentário no Twitter

 


Estudo randomizado | Suplementação de flavonóis de cacau mostrou-se promissora na prevenção de eventos cardiovasculares.

21 Mar, 2022 | 16:29h

Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial – American Journal of Clinical Nutrition

Comentário: New trial finds signs of preventive cardiovascular effects for cocoa flavanols – Brigham and Women’s Hospital

 

Comentário no Twitter (fio – clique para saber mais)

 


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