Dermatologia

Revisão | Diagnóstico e tratamento de infecções sexualmente transmissíveis.

13 Jan, 2022 | 21:04h

Diagnosis and Treatment of Sexually Transmitted Infections: A Review – JAMA (gratuito por tempo limitado)

Estudo randomizado | Em pacientes com melanoma avançado não tratado, o tratamento com relatimabe e nivolumabe foi associado com aumento na mediana de sobrevida livre de progressão em comparação com nivolumabe isolado (10,1 meses vs. 4,6 meses).

13 Jan, 2022 | 11:47h

Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentário: Relatlimab plus nivolumab improves progression-free survival in metastatic melanoma – University of Texas M. D. Anderson Cancer Center

Comentário no Twitter

The inhibition of two immune checkpoints, LAG-3 and PD-1, provided a greater benefit with regard to PFS than inhibition of PD-1 alone in patients with previously untreated metastatic or unresectable melanoma. https://t.co/idtOgksg74 pic.twitter.com/vx1W9O4Dh6

— NEJM (@NEJM) January 5, 2022

Estudos de fase 3 com tapinarofe em creme para psoríase em placas.

16 Dez, 2021 | 12:47h

Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis – New England Journal of Medicine

Comentário: Topical tapinarof reduces severity of plaque psoriasis – HealthDay

Comentário no Twitter

In two trials of treatment for psoriasis with the topical aryl hydrocarbon receptor–modulating agent tapinarof, clearance of lesions occurred in a larger proportion of patients who used tapinarof cream than of those who used placebo. https://t.co/I4zgVFELhz pic.twitter.com/qT6lbaJK0U

— NEJM (@NEJM) December 10, 2021

Breve revisão | Linfogranuloma venéreo.

14 Dez, 2021 | 16:00h

Lymphogranuloma venereum – Canadian Medical Association Journal

Estudo randomizado | Desfechos de longo prazo com nivolumabe associado a ipilimumabe ou nivolumabe isolado vs. ipilimumabe em pacientes com melanoma avançado.

6 Dez, 2021 | 15:51h

Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma – Journal of Clinical Oncology

Editorial: CheckMate-067: Raising the Bar for the Next Decade in Oncology – Journal of Clinical Oncology

Estudo original: #ESMO19 – Randomized Trial: Improved Overall Survival at 5 Years with Combined Immunotherapy for Advanced Melanoma

Revisão sistemática | Fototerapia para eczema atópico.

3 Dez, 2021 | 10:54h

Phototherapy for atopic eczema – Cochrane Library

Resumo: What are the benefits and risks of visible light therapy for treating atopic eczema (also known as eczema or atopic dermatitis)? – Cochrane Library

Comentário no Twitter

New @CochraneSkin systematic review casts some light on the topic of visible #LightTherapy for treating atopic eczema – ( #eczema or #atopicdermatitis ) https://t.co/JsrQwdqMHr 32 studies, involving 1219 people included. pic.twitter.com/6SfmlA2kWZ

— Cochrane UK (@CochraneUK) November 6, 2021