Acesso livre
Acesso livre

Covid-19

Revisão | Quando operar após infecção por SARS-CoV-2?

23 Mar, 2022 | 12:02h

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Conteúdos relacionados:

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

Infográfico | Mapa de diretrizes da IDSA para tratamento de pacientes ambulatoriais com COVID-19.

22 Mar, 2022 | 11:56h

COVID-19 Outpatient Treatment Guidelines Roadmap – Infectious Diseases Society of America

 

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Evolução antigênica levará a novas variantes do SARS-CoV-2 com gravidade imprevisível.

22 Mar, 2022 | 11:54h

Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity – Nature Reviews Microbiology

 

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Efetividade da vacina da Johnson & Johnson em profissionais da área da saúde na África do Sul no período em que as variantes de preocupação beta, e depois a delta, do SARS-CoV-2 eram dominantes.

22 Mar, 2022 | 11:52h

Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study – The Lancet

Comentário convidado: Sisonke: reaching several goals together – The Lancet

 

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Relatório do CDC | Efetividade da vacina de mRNA para evitar o uso de ventilação mecânica invasiva e morte associadas à COVID-19 nos EUA.

22 Mar, 2022 | 11:51h

Effectiveness of mRNA Vaccination in Preventing COVID-19–Associated Invasive Mechanical Ventilation and Death — United States, March 2021–January 2022 – CDC Morbidity and Mortality Weekly Report

Estudo relacionado: COVID-19–Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status — COVID-NET, 14 States, July 2021–January 2022 – CDC Morbidity and Mortality Weekly Report

Comentário: Studies show vaccines protect against serious Omicron illness – CIDRAP

 

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Miocardite após 3ª dose de vacina da Pfizer em recrutas militares em Israel.

22 Mar, 2022 | 11:49h

Myocarditis Following a Third BNT162b2 Vaccination Dose in Military Recruits in Israel – JAMA

Conteúdos relacionados:

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

M-A | Posição prona para pacientes não entubados com insuficiência respiratória hipoxêmica aguda relacionada à COVID-19.

21 Mar, 2022 | 16:33h

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Comentário convidado: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine

Conteúdos relacionados:

[Preprint] RCT: In hypoxic but not critically ill patients with COVID-19, an intervention to increase prone positioning did not improve outcomes.

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

Estudo mostra que não há risco aumentado de eventos neurológicos raros após vacinação contra Covid.

21 Mar, 2022 | 16:31h

Comunicado de imprensa: Study finds no increased risk of rare neurological events after covid vaccination – BMJ Newsroom

Estudo original: Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis – The BMJ

Editorial: The neurological safety of covid-19 vaccines

Uso da redução no risco absoluto para orientar a distribuição equitativa das vacinas contra COVID-19.

21 Mar, 2022 | 16:30h

Using absolute risk reduction to guide the equitable distribution of COVID-19 vaccines – BMJ Evidence-Based Medicine

Comunicado de imprensa: Researchers find equitable COVID-19 vaccine distribution can target risks in different geographical areas – University of New Mexico

 

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Decisão do consenso de especialistas da ACC de 2022 sobre sequelas cardiovasculares de COVID-19 em adultos: miocardite e outros envolvimentos miocárdicos, sequelas pós-agudas da infecção pelo SARS-CoV-2 e volta aos esportes.

17 Mar, 2022 | 13:25h

2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Comentários:

ACC Issues Clinical Guidance on CV Consequences of COVID-19 – American College of Cardiology

ACC Releases Guidance on CV Issues With COVID-19 – TCTMD

Pontos principais: 2022 ACC Decision Pathway on Cardiovascular Sequelae of COVID-19

Conteúdos relacionados:

Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.

The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.

COVID-19 infections increase risk of heart conditions up to a year later, study finds.

 

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