Covid-19

Estudo de caso-controle e teste negativo: efetividade dos reforços vacinais homólogos e heterólogos contra a variante Ômicron da COVID-19.

27 Mai, 2022 | 13:38h

Effectiveness of Homologous and Heterologous Covid-19 Boosters against Omicron – New England Journal of Medicine

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Efetividade da CoronaVac em crianças de 3 a 5 anos durante o surto da variante Ômicron do SARS-CoV-2 no Chile.

26 Mai, 2022 | 13:24h

Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile – Nature Medicine

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Estudo randomizado | Baricitinibe vs. dexametasona para adultos internados com COVID-19.

26 Mai, 2022 | 13:23h

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial – The Lancet Respiratory Medicine

 

Comentário no Twitter

💥Just Out
ACTT-4 Trial👉First Double Placebo-Controlled Double-Blind Randomized-Stratified Head-to-Head#DEXAMETHASONE vs #BARICITINIB for hospitalized pts w/#COVID19 Low/High-Flow/NIV
Relevant👉Patient Care/Public Health/Guidelines
Our results
👇https://t.co/4Tmue7HK7V
🧵1/4 pic.twitter.com/aF1Y7BAdu3

— Andre Kalil, MD MPH (@DrAndreKalil) May 24, 2022

 

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Efetividade relativa e de curto prazo de 4 doses vs. 3 doses de vacina BNT162b2 em pessoas com 60 anos de idade ou mais em Israel: estudo retrospectivo, de caso-controle teste negativo.

26 Mai, 2022 | 13:21h

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Recomendações relacionadas:

Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO – The BMJ

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines –
European Centre for Disease Prevention and Control

Coronavirus (COVID-19) Update: FDA Authorizes Second Booster Dose of Two COVID-19 Vaccines for Older and Immunocompromised Individuals – U.S. Food & Drug Administration

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Breve atualização de diretriz NICE sobre tratamento de Covid-19.

24 Mai, 2022 | 11:54h

COVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence

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Estudo randomizado | Segurança e imunogenicidade da imunização com reforço heterólogo usando Ad5-nCoV em aerossol oral após 2 doses prévias de vacina com SARS-CoV-2 inativado em adultos na China.

24 Mai, 2022 | 11:52h

Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial – The Lancet Respiratory Medicine

 

Comentário no Twitter

Mix-and-match typically refers to different shots. Here's a randomized trial of shots and an oral vaccine that ameliorates the immune responsehttps://t.co/FFWHEwS37Y @LancetRespirMed pic.twitter.com/JZyvrxCalS

— Eric Topol (@EricTopol) May 21, 2022

 

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Estudo randomizado | Oxigênio nasal de alto fluxo não é benéfico para pacientes com pneumonia por Covid-19 e hipoxemia leve.

24 Mai, 2022 | 11:51h

High-flow nasal oxygen versus conventional oxygen therapy in patients with COVID-19 pneumonia and mild hypoxaemia: a randomised controlled trial – Thorax

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OMS valida a 11ª vacina contra COVID-19.

23 Mai, 2022 | 13:37h

WHO validates 11th vaccine for COVID-19 – World Health Organization

 

Comentário no Twitter

WHO issued an emergency use listing for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of #COVID19 vaccines validated by WHO https://t.co/QdpHiasT2p pic.twitter.com/2B54FwiNDl

— World Health Organization (WHO) (@WHO) May 19, 2022

 

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Evidência sobre COVID-19: uma coletânea Cochrane.

23 Mai, 2022 | 13:36h

COVID-19 evidence: a Cochrane round-up – Cochrane Library

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Revisão sistemática | Exames de imagem torácica para diagnóstico de COVID-19.

23 Mai, 2022 | 13:34h

Thoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library

Resumo: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library

Conteúdo relacionado: Review of Thoracic Imaging Manifestations of COVID-19 and Other Pathologic Coronaviruses – Radiology Clinics of North America

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