Acesso livre
Acesso livre

Covid-19 (Temas de Saúde Pública)

Falsas dicotomias da COVID-19 e uma revisão ampla das evidências a respeito de saúde pública, sintomatologia da COVID-19, transmissão do SARS-CoV-2, uso de máscara e reinfecção.

2 Ago, 2021 | 17:41h

COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection – BMC Infectious Diseases

 

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“Breakthrough infections” (infecções em indivíduos já vacinados) por Covid-19 em trabalhadores da área da saúde.

2 Ago, 2021 | 17:39h

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine

 

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O que é “breakthrough infection”? 6 questões e respostas sobre infecções por SARS-CoV-2 adquiridas após vacinação.

2 Ago, 2021 | 17:38h

What is a breakthrough infection? 6 questions answered about catching COVID-19 after vaccination – The Conversation

Vacinas contra COVID-19 diminuem a disseminação viral, mas a variante Delta é um fator desconhecido – “Estudos mostram que as vacinas reduzem a disseminação do SARS-CoV-2 em mais de 80%, mas a variante Delta está criando uma nova incerteza.”

2 Ago, 2021 | 17:36h

COVID vaccines slash viral spread – but Delta is an unknown – Nature

Dados mostram que a eficácia da vacina da Pfizer/BioNTech contra Covid cai para 84% depois de 6 meses.

2 Ago, 2021 | 17:35h

Efficacy of Pfizer/BioNTech Covid vaccine slips to 84% after six months, data show – STAT

Estudo original (preprint): Six Month Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine – medRxiv

 

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CDC muda as diretrizes para uso de máscaras em resposta à ameaça da variante Delta da Covid-19.

2 Ago, 2021 | 17:06h

Comentário: CDC changes mask guidance in response to threat of Delta variant of Covid-19 – CNN

Ver diretriz: Guidance for Implementing COVID-19 Prevention Strategies in the Context of Varying Community Transmission Levels and Vaccination Coverage – Centers for Disease Control and Prevention

 

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Casos muito raros da síndrome de trombose com trombocitopenia (STT) após vacina AstraZeneca – A estimativa de STT após a primeira dose foi de 8,1 por milhão de vacinas; depois da segunda dose, a estimativa foi de 2,3 por milhão de vacinas.

2 Ago, 2021 | 17:05h

Very rare thrombosis with thrombocytopenia after second AZD1222 dose: a global safety database analysis – The Lancet

Conteúdos relacionados:

WHO Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19).

AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.”

ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia

Case series: therapeutic plasma exchange in 3 patients with vaccine-induced immune thrombotic thrombocytopenia.

Vaccine-induced immune thrombotic thrombocytopenia (VITT) – a novel clinico-pathological entity with heterogeneous clinical presentations.

Case report: Thrombosis with Thrombocytopenia After the Messenger RNA–1273 Vaccine.

Laboratory testing for suspected COVID-19 vaccine–induced (immune) thrombotic thrombocytopenia.

Concerned about the latest AstraZeneca news? These 3 graphics help you make sense of the risk – “Two people in Australia have died from thrombosis with thrombocytopenia after 3.8 million doses of the AstraZeneca vaccine delivered”.

Case series: Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia.

Case report: Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).

[Preprint] Meta-analysis of risk of vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1-S recombinant vaccine – Overall risk is 1 in 139,000; for age 65 and over, about 1 in 1,000,000; for age under 55, between 1 in 20,000 to 60,000.

Cohort study: Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S. 11 excess venous thromboembolic events per 100 000 vaccinations; 2.5 excess cerebral venous thrombosis per 100 000 vaccinations.

Case series of 12 patients with cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccination – all women younger than 60 years, with symptoms from 6 to 15 days after vaccination

Vaccine-induced Immune Thrombotic Thrombocytopenia: Frequently Asked Questions

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination

Editorial: SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – “The very low prevalence of this complication of vaccination, however severe, relative to the benefits of preventing Covid-19 must be emphasized”

Case Report: Thrombotic Thrombocytopenia after Johnson & Johnson Vaccine

Papers Confirm Rare Thrombocytopenia Link to AstraZeneca Vaccine

Guidance on syndrome of Thrombosis and Thrombocytopenia occurring after coronavirus Vaccination

 

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Editorial | 9 lições aprendidas com a pandemia da Covid-19 para a melhoria dos cuidados hospitalares e dos serviços de saúde.

2 Ago, 2021 | 17:02h

Nine Lessons Learned From the COVID-19 Pandemic for Improving Hospital Care and Health Care Delivery – JAMA Internal Medicine

Relatório | Engenheiros afirmam que melhorias na ventilação são essenciais para o uso seguro de espaços públicos.

2 Ago, 2021 | 16:59h

Comunicado de imprensa: Improved ventilation essential to safe use of buildings and public spaces, say leading engineers – Royal Academy of Engineering

Relatório: Infection Resilient Environments: Buildings that keep us healthy and safe – National Engineering Policy Centre

Conteúdos relacionados:

WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19

CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk

Guidance: Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes

 

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Transmissão domiciliar do SARS-CoV-2 por crianças e adolescentes.

2 Ago, 2021 | 16:54h

Household Transmission of SARS-CoV-2 from Children and Adolescents – New England Journal of Medicine

Conteúdos relacionados:

Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients”.

Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.

Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose

Study: Household transmission of SARS-CoV-2 and risk factors for susceptibility and infectivity

A meta-analysis on the role of children in SARS-CoV-2 in household transmission clusters

Report: SARS-CoV-2 setting-specific transmission rates. Households showed the highest transmission rates (21.1%). Asymptomatic infections do occur but much less efficiently than symptomatic infection.

CDC Report: Transmission of SARS-COV-2 infections in households

The household secondary attack rate of SARS-CoV-2: A rapid review

 

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