Acesso livre
Acesso livre

Covid-19 (Temas de Saúde Pública)

Perspectiva | Como a pandemia terminará.

13 Ago, 2021 | 12:29h

How the pandemic now ends – The Atlantic

 

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Como pessoas vacinadas disseminam a variante Delta? O que diz a ciência.

13 Ago, 2021 | 12:24h

How do vaccinated people spread Delta? What the science says – Nature


Opinião | Hora de uma abordagem inteligente das doses de reforço.

13 Ago, 2021 | 12:20h

Time for a Smart Approach to Boosters – Think Global Health


Opinião | Disponibilização das vacinas para outros países antes de fazer uma vacinação doméstica de reforço.

13 Ago, 2021 | 12:18h

Making Vaccines Available to Other Countries Before Offering Domestic Booster Vaccinations – JAMA


Estudo randomizado | Avaliação da vacina de mRNA da Moderna em adolescentes.

12 Ago, 2021 | 12:30h

Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents – New England Journal of Medicine

Conteúdos relacionados:

Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%).

 

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Estudo randomizado | Terceira dose da vacina de mRNA da Moderna aumenta a imunidade em receptores de transplantes.

12 Ago, 2021 | 12:28h

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients – New England Journal of Medicine

Editorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients

Conteúdos relacionados:

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

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Vacina da Moderna pode ser superior à vacina da Pfizer contra a variante Delta.

12 Ago, 2021 | 12:25h

Moderna may be superior to Pfizer against delta variant — breakthrough odds rise with time – CNBC

Estudo original 1 (preprint): Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence – medRxiv

Estudo original 2 (preprint): Neutralizing antibody responses to SARS-CoV-2 variants in vaccinated Ontario long-term care home residents and workers – medRxiv

Conteúdo relacionado: Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.


[Preprint] Efetividade das vacinas da Pfizer vs. Moderna contra a variante Delta da COVID-19 no Catar – A efetividade contra doença sintomática causada pela variante Delta foi de 53,5% para a vacina da Pfizer e de 84,8% para a da Moderna; a efetividade contra doença grave pela mesma variante foi de 89,7% para Pfizer e de 100% para a Moderna.

12 Ago, 2021 | 12:23h

BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the Delta (B.1.617.2) variant in Qatar – medRxiv

Conteúdo relacionado: Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

 

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Estudo clínico Solidarity da OMS entra em uma nova fase com 3 novas drogas candidatas.

12 Ago, 2021 | 12:18h

WHO’s Solidarity clinical trial enters a new phase with three new candidate drugs – World Health Organization

Comentário: WHO-led Trial Will Test Malaria and Cancer Medicines Against COVID-19 – Health Policy Watch

Conteúdos relacionados:

A giant trial of COVID-19 treatments organized by the WHO is restarting. Here are the drugs it’s betting on.

WHO Solidarity trial to restart with focus on drugs that act on immune responses caused by Covid-19.

 

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Vacinação: Efetividade versus eficácia.

12 Ago, 2021 | 12:17h

Vaccination: Effectiveness versus Efficacy – by Luis Correa, MD


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