Covid-19 (Temas de Saúde Pública)

A dose of the AstraZeneca COVID-19 vaccine followed by a dose of the Pfizer/BioNTech vaccine confers better protection against SARS-CoV-2 infection than two doses of the Pfizer vaccine, according to a study in healthcare workers published in @Nature. https://t.co/6hIVkiOLQ1 pic.twitter.com/AmsyVUMpoj

— Nature Portfolio (@NaturePortfolio) October 26, 2021

Diferentes vacinas contra COVID misturadas e combinadas com sucesso no teste de efetividade – “Não é preciso se restringir a nenhuma marca.”

27 Out, 2021 | 12:39h

Mix-and-match COVID vaccines ace the effectiveness test – Nature

Conteúdos relacionados:

Should You Mix and Match Your Booster Shot?

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

O que a teoria dos jogos pode ensinar sobre o controle de pandemias.

27 Out, 2021 | 12:36h

What game theory can teach us about controlling pandemics – The BMJ Opinion

Comentário no Twitter

Sorry but panvax is just covax with money and better/early contracts – What game theory can teach us about controlling pandemics – The BMJ https://t.co/bZyhfxCkP3

— Amanda Glassman (@glassmanamanda) October 22, 2021

[Comunicado de imprensa – ainda não publicado] Moderna afirma que sua vacina contra COVID produz forte resposta imunológica em crianças de 6 a 11 anos.

26 Out, 2021 | 11:36h

Comunicado de imprensa: Moderna Announces Positive Top Line Data from Phase 2/3 Study of COVID-19 Vaccine in Children 6 to 11 Years of Age

Comentário: Moderna says new data supports its COVID vaccine for kids 6 to 11 – NPR

Infecção por Covid-19 traz um risco muito maior de desenvolvimento de complicações neurológicas do que as vacinas contra Covid-19.

26 Out, 2021 | 11:34h

Comunicado de imprensa: Infection with Covid-19 carries a much higher risk of developing neurological complications than a vaccine, says new study – University of Nottingham

Estudo original: Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection – Nature Medicine

Comentários:

Covid: Vaccine study links virus to rare neurological illness – BBC

Expert reaction to study looking at rare neurological complications after SARS-CoV-2 infection and COVID-19 vaccination – Science Media Centre

Comentários no Twitter

A study in @NatureMedicine finds there is an increased risk of neurological complications in those who received COVID-19 vaccines, but the risk of these complications is greater following a positive SARS-CoV-2 test. https://t.co/WKnFa9InbL pic.twitter.com/xir6U3JhL8

— Nature Portfolio (@NaturePortfolio) October 25, 2021

COVID: qual deve ser o nível de preocupação quanto à nova linhagem AY.4.2 do coronavírus?

26 Out, 2021 | 11:31h

COVID: how worried should we be about the new AY.4.2 lineage of the coronavirus? – The Conversation

O que significa estar totalmente vacinado.

26 Out, 2021 | 11:28h

What It Means To Be Fully Vaccinated – Think Global Health

Vacina da AstraZeneca não se associou a taxas reduzidas de fertilidade nem a desfechos adversos ao nascimento.

25 Out, 2021 | 13:05h

Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination – The Lancet

Conteúdos relacionados:

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

Comentário no Twitter

New research letter: Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination. Authors analysed pregnancies occurring in four ongoing clinical trials in the UK, Brazil, and South Africa. https://t.co/hDM1olKts9 @OxfordVacGroup | #COVID19 #AstraZeneca pic.twitter.com/m5qvWhPcph

— The Lancet (@TheLancet) October 23, 2021

Como identificar quando a Covid-19 deixará de ser “pandêmica” para se tornar “endêmica”.

25 Out, 2021 | 13:03h

How you’ll know when Covid-19 has gone from “pandemic” to “endemic” – Vox

Covid-19 em indivíduos já vacinados ocorre com mais frequência naqueles com baixos níveis de anticorpos.

Vacinação heteróloga AstraZeneca/Pfizer parece estar associada com maior efetividade contra Covid-19 em comparação com a vacinação homóloga Pfizer/Pfizer.