Acesso livre
Acesso livre

Covid-19 (Temas de Saúde Pública)

Correlação entre o aumento de infecções por SARS-CoV-2 e o tempo de vacinação.

19 Nov, 2021 | 13:11h

Correlation of SARS-CoV-2-breakthrough infections to time-from-vaccine – Nature Communications

Comentário: Long-term effectiveness of Pfizer/BioNTech two-dose regimen mRNA vaccine – News Medical

China’s COVID vaccines have been crucial — now immunity is waning.

[Preprint] Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – “Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%”.

Observational study in Qatar showed the effectiveness of Pfizer vaccine against any SARS-CoV-2 infection dropped to 20% in months 5 through 7 after the second dose, but effectiveness against severe Covid-19 remained high.

Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning.

Editorial | Covid-19 vaccination: evidence of waning immunity is overstated.

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

COVID vaccine effects wane over time but still prevent death and severe illness.

Perspective | What we actually know about waning immunity.

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

 

Comentário no Twitter

 

Opinião | Com 128 vacinas contra Covid em desenvolvimento clínico, não se sabe se as aprovadas/autorizadas são as melhores.

19 Nov, 2021 | 13:09h

With 128 Covid vaccines in clinical development, we don’t know if the approved/authorized ones are the best ones – STAT

M-A | Efetividade das medidas de saúde pública na redução da incidência de Covid-19, na transmissão do SARS-CoV-2 e na mortalidade por Covid-19.

19 Nov, 2021 | 12:38h

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis – The BMJ

 

Comentário no Twitter

 

Revisão | Crianças com menos de 12 anos deveriam ser vacinadas contra COVID-19?

19 Nov, 2021 | 12:37h

Should children be vaccinated against COVID-19? – Archives of Disease in Childhood

 

Comentário do autor no Twitter (fio – clique para saber mais)

 

Covid: no Reino Unido, crianças só devem tomar a dose da vacina 12 semanas depois de uma infecção.

19 Nov, 2021 | 12:35h

Covid: Children told to delay jab for 12 weeks after infection – BBC

Relatório original: Joint Committee on Vaccination and Immunisation (JCVI) advice on COVID-19 vaccination in people aged 16 to 17 years: 15 November 2021

Estudo observacional mostra que a efetividade de vacinas mRNA contra internação por Covid-19 entre adultos imunocomprometidos foi menor (77%) do que entre adultos imunocompetentes (90%).

19 Nov, 2021 | 12:33h

Effectiveness of 2-Dose Vaccination with mRNA COVID-19 Vaccines Against COVID-19–Associated Hospitalizations Among Immunocompromised Adults — Nine States, January–September 2021 – CDC Morbidity and Mortality Weekly Report

Conteúdo relacionado: CDC Guidance: Immunocompromised may need a fourth Covid-19 shot.

 

Comentário no Twitter (fio – clique para saber mais)

 

Estudo observacional mostra que as vacinas mRNA estão associadas à efetividade de 85% contra internação por Covid-19.

19 Nov, 2021 | 12:31h

Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity – JAMA

Editorial: Understanding Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination – JAMA

Comentário: COVID-19 vaccines 85% effective against hospital cases but weaken over time – TCTMD

Estudo relacionado: Study compares the decline in effectiveness for Moderna, Pfizer, and Janssen vaccines and consequences for mortality.

8 questões sobre as novas pílulas da Merck e da Pfizer contra Covid.

19 Nov, 2021 | 12:28h

8 lingering questions about the new Covid pills from Merck and Pfizer – STAT

Conteúdos relacionados:

COVID antiviral pills: what scientists still want to know – “Drugs like Molnupiravir and Paxlovid could change the course of the pandemic if clinical trial results hold up in the real world”.

[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.

A prominent virologist warns new COVID-19 pill could unleash dangerous mutants. Others see little cause for alarm.

The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.

Merck to allow other nations to produce new COVID-19 antiviral.

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

Estudo observacional mostra que o monitoramento de pacientes com Covid-19 via mensagens de texto, propiciando que eles relatassem a piora dos sintomas, foi associado a desfechos melhores.

17 Nov, 2021 | 13:10h

Comparative Effectiveness of an Automated Text Messaging Service for Monitoring COVID-19 at Home – Annals of Internal Medicine

Comunicado de imprensa: Automated Texting System Saved Lives Weekly During First COVID Surge – Penn Medicine

Comentários:

Monitoring outpatients by text appeared to reduce mortality from COVID-19 – ACP Internist

Texting saved lives during Covid. What does that mean for health care’s future? – STAT

 

Comentário do autor no Twitter (fio – clique para saber mais)

 

Grandes questões sobre as doses de reforço das vacinas contra Covid-19 – “Desde o porquê até para quem, ainda precisamos de muitas respostas sobre as doses de reforço.”

17 Nov, 2021 | 13:06h

The big questions about Covid-19 booster shots – Vox

 

Comentário no Twitter

 

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