Clínica Médica

Estudo de coorte | Incidência do diabetes tipo 2 de início recente após câncer.

14 Jun, 2022 | 13:28h

Incidence of New-Onset Type 2 Diabetes After Cancer: A Danish Cohort Study – Diabetes Care

Comunicado de imprensa: Cancer Increases the Risk of Developing Diabetes – University of Copenhagen

Comentários no Twitter

We identify several cancers as risk factor for T2D with associated ↑21% risk of death as consequence. Fantastic cross-disciplinary collaboration @CASTLE_research @FessorC @FrederikPersson @NEXSKU @BiomedUCPH @ADA_DiabetesPro @Rigshospitalet @Stenodiabetes https://t.co/LYDsDXSGNB pic.twitter.com/PdOZffSjFf

— Lykke Sylow (@LykkeSylow) June 2, 2022

Patients with cancer are at higher risk for developing diabetes (esp patients with pancreatic cancer (HR 5.00), brain tumours (HR 1.54) and uterine cancer (HR 1.41) https://t.co/FzjepMrENA pic.twitter.com/PWDs5xsHOn

— K Pavithran (@drkpavithran) June 3, 2022

Revisão sistemática | Produtos feitos à base de Cannabis para dor crônica.

14 Jun, 2022 | 13:24h

Cannabis-Based Products for Chronic Pain: A Systematic Review – Annals of Internal Medicine

Resumo dos anais em vídeo: Cannabis-Based Products for Chronic Pain: A Systematic Review

Resumo para pacientes: Cannabis-Based Products for Chronic Pain

Conteúdos relacionados:

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

Combinação de infusões de anticorpos anti-HIV suprimem o vírus por período prolongado.

14 Jun, 2022 | 13:21h

Comunicado de imprensa: Combination anti-HIV antibody infusions suppress virus for prolonged period – National Institutes of Health

Estudo original: Combination anti-HIV antibodies provide sustained virological suppression – Nature

Comentários no Twitter

Still don't get the enthusiasm for HIV Rx with bNAbs.
Compared to existing antivirals, they have:
– more baseline resistance
– the need to scale up new resistance tests
– more resource requirements (IV administration)
– … and, if like other monoclonals, $$$
What am I missing? https://t.co/7WZmIjutwE

— Paul Sax (@PaulSaxMD) June 1, 2022

This is a wonderful advance.

"Our data demonstrate that combination therapy with broadly neutralizing monoclonal antibodies can provide long-term virological suppression without antiretroviral therapy in individuals with HIV"https://t.co/DKNVSlg3mC

— Michael Worobey (@MichaelWorobey) June 2, 2022